Janice Chung

发表

Expedited SAR study of an mGluR5 antagonists: generation of a focused library using a solution-phase Suzuki coupling methodology.

N. Cosford, B. Muñoz, Nicholas D Smith, 2004, Bioorganic & medicinal chemistry letters.

3-[3-Fluoro-5-(5-pyridin-2-yl-2H-tetrazol-2-yl)phenyl]-4-methylpyridine: a highly potent and orally bioavailable metabotropic glutamate subtype 5 (mGlu5) receptor antagonist.

N. Cosford, Merryl D. Cramer, Nicholas D Smith, 2004, Bioorganic & medicinal chemistry letters.

Discovery of novel heteroarylazoles that are metabotropic glutamate subtype 5 receptor antagonists with anxiolytic activity.

N. Cosford, P. Prasit, B. Muñoz, 2004, Journal of medicinal chemistry.

Discovery of novel modulators of metabotropic glutamate receptor subtype-5.

B. Muñoz, M. F. Gardner, Janice Chung, 2004, Bioorganic & medicinal chemistry.

Cyclohexenyl- and dehydropiperidinyl-alkynyl pyridines as potent metabotropic glutamate subtype 5 (mGlu5) receptor antagonists.

N. Cosford, B. Muñoz, Merryl D. Cramer, 2005, Bioorganic & medicinal chemistry letters.

2-(2-[3-(pyridin-3-yloxy)phenyl]-2H-tetrazol-5-yl) pyridine: a highly potent, orally active, metabotropic glutamate subtype 5 (mGlu5) receptor antagonist.

Dehua Huang, N. Cosford, Merryl D. Cramer, 2004, Bioorganic & medicinal chemistry letters.

3‐[3‐Fluoro‐5‐(5‐pyridin‐2‐yl‐2H‐tetrazol‐2‐yl)phenyl] ‐4‐methylpyridine: A Highly Potent and Orally Bioavailable Metabotropic Glutamate Subtype 5 (mGlu5) Receptor Antagonist.

N. Cosford, Merryl D. Cramer, G. Holtz, 2005 .

5-[(2-Methyl-1,3-thiazol-4-yl)ethynyl]-2,3'-bipyridine: a highly potent, orally active metabotropic glutamate subtype 5 (mGlu5) receptor antagonist with anxiolytic activity.

Dehua Huang, N. Cosford, B. Muñoz, 2004, Bioorganic & medicinal chemistry letters.

Discovery of highly potent, selective, orally bioavailable, metabotropic glutamate subtype 5 (mGlu5) receptor antagonists devoid of cytochrome P450 1A2 inhibitory activity.

Dehua Huang, N. Cosford, Merryl D. Cramer, 2004, Bioorganic & medicinal chemistry letters.

3-[Substituted]-5-(5-pyridin-2-yl-2H-tetrazol-2-yl)benzonitriles: identification of highly potent and selective metabotropic glutamate subtype 5 receptor antagonists.

N. Cosford, Merryl D. Cramer, J. Roppe, 2005, Bioorganic & medicinal chemistry letters.

Cyclohexenyl- and dehydropiperidinyl-alkynyl pyridines as potent metabotropic glutamate subtype 5 (mGlu5) receptor antagonists.

N. Cosford, B. Muñoz, Merryl D. Cramer, 2005, Bioorganic & medicinal chemistry letters.

Dipyridyl amides: potent metabotropic glutamate subtype 5 (mGlu5) receptor antagonists.

T. Kamenecka, C. Bonnefous, Janice Chung, 2005, Bioorganic & medicinal chemistry letters.

2‐{2‐[3‐(Pyridin‐3‐yloxy)phenyl]‐2H‐tetrazol‐5‐yl}pyridine: A Highly Potent, Orally Active, Metabotropic Glutamate Subtype 5 (mGlu5) Receptor Antagonist.

N. Cosford, Merryl D. Cramer, J. Roppe, 2005 .

Dipyridyl amines: potent metabotropic glutamate subtype 5 receptor antagonists.

T. Kamenecka, C. Bonnefous, J. Vernier, 2005, Bioorganic & medicinal chemistry letters.