A. Humphries

发表

Non-basic ligands for aminergic GPCRs: the discovery and development diaryl sulfones as selective, orally bioavailable 5-HT2A receptor antagonists for the treatment of sleep disorders.

M. Ivarsson, D. O'connor, A. Macleod, 2010, Bioorganic & medicinal chemistry letters.

Design driven HtL: The discovery and synthesis of new high efficacy β₂-agonists.

G. Pairaudeau, A. Bailey, E. Cadogan, 2011, Bioorganic & medicinal chemistry letters.

Design-driven LO: the discovery of new ultra long acting dibasic β2-adrenoceptor agonists.

G. Pairaudeau, A. Bailey, E. Cadogan, 2011, Bioorganic & medicinal chemistry letters.

Discovery of AZD3199, An Inhaled Ultralong Acting β2 Receptor Agonist with Rapid Onset of Action.

G. Pairaudeau, A. Bailey, E. Cadogan, 2014, ACS medicinal chemistry letters.

The asymmetric Maitland-Japp reaction and its application to the construction of the C1-C19 bis-pyran unit of phorboxazole B.

Laurence Burroughs, A. Humphries, P. Clarke, 2011, Organic letters.

8-Fluoroimidazo[1,2-a]pyridine: synthesis, physicochemical properties and evaluation as a bioisosteric replacement for imidazo[1,2-a]pyrimidine in an allosteric modulator ligand of the GABA A receptor.

E. Gancia, D. Hallett, Myra T Gilligan, 2006, Bioorganic & medicinal chemistry letters.

Total synthesis of the protein phosphatase inhibitor okadaic acid

S. Ley, J. Pietruszka, Robert Downham, 1998 .

A Brønsted acid mediated cascade enone synthesis from aldehydes containing a tethered propargylsilane.

B. Kariuki, P. Jervis, A. Humphries, 2008, The Journal of organic chemistry.

Evidence for a Significant Role of α3-Containing GABAA Receptors in Mediating the Anxiolytic Effects of Benzodiazepines

G. Dawson, R. Dias, S. Tye, 2005, The Journal of Neuroscience.

4-Fluorosulfonylpiperidines: selective 5-HT2A ligands for the treatment of insomnia.

M. Ivarsson, D. O'connor, P. Hutson, 2005, Bioorganic & medicinal chemistry letters.

The discovery of AZD 3199 A new inhaled ultra-long acting 2 receptor agonist with rapid onset of action

David, A. Bailey, E. Cadogan, 2014 .