S. Bisaha

发表

Biphenylsulfonamide endothelin antagonists: structure-activity relationships of a series of mono- and disubstituted analogues and pharmacology of the orally active endothelin antagonist 2'-amino-N- (3,4-dimethyl-5-isoxazolyl)-4'-(2-methylpropyl)[1, 1'-biphenyl]-2-sulfonamide (BMS-187308).

S. Spergel, N. Murugesan, Z. Gu, 1998, Journal of medicinal chemistry.

N-[1-Aryl-2-(1-imidazolo)ethyl]-guanidine derivatives as potent inhibitors of the bovine mitochondrial F1F0 ATP hydrolase.

K. J. Yost, Hsinglin Lan, L. Hamann, 2004, Bioorganic & medicinal chemistry letters.

Synthesis and biological evaluation of antiplatelet 2-aminochromones.

D. Wishka, S. Bisaha, J. Morris, 1993, Journal of medicinal chemistry.

Aroylguanidine-based factor Xa inhibitors: the discovery of BMS-344577.

J. Yanchunas, K. Kish, H. Klei, 2009, Bioorganic & medicinal chemistry letters.

(3R,5S,E)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(methyl(1-methyl-1h-1,2,4-triazol-5-yl)amino)pyrimidin-5-yl)-3,5-dihydroxyhept-6-enoic acid (BMS-644950): a rationally designed orally efficacious 3-hydroxy-3-methylglutaryl coenzyme-a reductase inhibitor with reduced myotoxicity potential.

J. Barrish, M. Blanar, Rongan Zhang, 2008, Journal of medicinal chemistry.

Design and synthesis of 4-substituted benzamides as potent, selective, and orally bioavailable I(Ks) blockers.

A. Mathur, P. Stein, M. Conder, 2001, Journal of Medicinal Chemistry.

Design and synthesis of 4-substituted benzamides as potent, selective, and orally bioavailable IKs blockers

A. Mathur, P. Stein, Mark A. Smith, 2001 .

Biphenylsulfonamide endothelin receptor antagonists. Part 3: structure-activity relationship of 4'-heterocyclic biphenylsulfonamides.

S. Spergel, J. Barrish, N. Murugesan, 2002, Bioorganic & medicinal chemistry letters.

Tetrahydronaphthalene-derived amino alcohols and amino ketones as potent and selective inhibitors of the delayed rectifier potassium current IKs.

John Lloyd, Saleem Ahmad, P. Stein, 2004, Bioorganic & medicinal chemistry letters.

Synthesis and SAR of potent and selective tetrahydropyrazinoisoquinolinone 5-HT(2C) receptor agonists.

P. Stein, Xueying Cao, M. Pelleymounter, 2013, Bioorganic & medicinal chemistry letters.

Discovery of nonbenzamidine factor VIIa inhibitors using a biaryl acid scaffold.

D. Cheney, S. Sheriff, E. Liu, 2013, Bioorganic & medicinal chemistry letters.

Synthesis and Antiobesity Properties of 6-(4-Chlorophenyl)-3-(4-((3,3-difluoro-1-hydroxycyclobutyl)methoxy)-3-methoxyphenyl)thieno[3,2-d]pyrimidin-4(3H)-one (BMS-814580): A Highly Efficacious Melanin Concentrating Hormone Receptor 1 (MCHR1) Inhibitor.

E. Janovitz, D. Longhi, Christine S. Huang, 2016, Journal of Medicinal Chemistry.

Cyanoguanidine-based lactam derivatives as a novel class of orally bioavailable factor Xa inhibitors.

S. Chong, J. Yanchunas, K. Kish, 2009, Bioorganic & medicinal chemistry letters.

Ketene aminal-based lactam derivatives as a novel class of orally active FXa inhibitors.

E. Liu, P. Stein, A. Rendina, 2005, Bioorganic & medicinal chemistry letters.

Arylsulfonamidopiperidone derivatives as a novel class of factor Xa inhibitors.

Ying Wang, Doree Sitkoff, Jing Zhang, 2011, Bioorganic & medicinal chemistry letters.

Antiatherosclerotic agents. A structurally novel bivalent inhibitor of acylCoA:cholesterol O-acyltransferase with systemic activity.

S. Bisaha, G. J. Wilson, R. B. Gammill, 1990, Journal of medicinal chemistry.

Conformationally restricted P1-P1' transition state analogues. Synthesis of 1(R), 3(R) [1(S), 2(S)] and 1(S), 3(S) [1(S), 2(S)] 3-[3-cyclohexyl-2-[(BOC)amino]-1-hydroxypropyl]-2,2-dimethylcyclo propane carboxylic acids

S. Bisaha, R. B. Gammill, M. Melnick, 1990 .

A switch in enantiomer preference between mitochondrial F1F0-ATPase chemotypes.

P. Stein, C. S. Madsen, H. Monshizadegan, 2005, Bioorganic & medicinal chemistry letters.

Discovery and structure-activity relationships of sulfonamide ETA-selective antagonists.

E. Liu, P. Stein, D. Floyd, 1995, Journal of medicinal chemistry.