D. Morgans

发表

Identification of the Binding Site for a Novel Class of CCR2b Chemokine Receptor Antagonists

Frank Diehl, K. Jarnagin, R. Wilhelm, 2000, The Journal of Biological Chemistry.

Improvement of Cardiac Function by a Cardiac Myosin Activator in Conscious Dogs With Systolic Heart Failure

S. Vatner, P. Abarzúa, C. Depré, 2010, Circulation. Heart failure.

Dual inhibition of αvβ6 and αvβ1 reduces fibrogenesis in lung tissue explants from patients with IPF

T. Desai, P. Wolters, L. Hooi, 2021, Respiratory Research.

1,2 Asymmetric induction in the cyclic hydroboration of 1,5-dienes. A synthesis of the Prelog-Djerassi lactone

D. Morgans, 1982 .

Discovery of omecamtiv mecarbil the first, selective, small molecule activator of cardiac Myosin.

Whitney W. Smith, X. Qian, Hong Jiang, 2010, ACS medicinal chemistry letters.

Discovery of the First Potent and Selective Inhibitor of Centromere-Associated Protein E: GSK923295.

J. D. Elliott, Nicholas D. Adams, X. Qian, 2010, ACS medicinal chemistry letters.

Activating Cardiac Myosin, a Novel Inotropic Mechanism To Improve Cardiac Function in Conscious Dogs with Congestive Heart Failure

S. Vatner, You-tang Shen, D. Morgans, 2006 .

Smooth Muscle Myosin Inhibition: A Novel Therapeutic Approach for Pulmonary Hypertension

S. Vatner, D. Vatner, You-tang Shen, 2012, PloS one.

PARP 2 Identified Using a Cell-based Screen in Yeast Novel Inhibitors of Poly ( ADP-ribose ) Polymerase / PARP 1 and Updated

K. Jarnagin, S. Tugendreich, Ajay Jain, 2001 .

Selective inhibition of prostaglandin endoperoxide synthase-1 (cyclooxygenase-1) by valerylsalicylic acid.

W. Smith, M. Lecomte, D. Bhattacharyya, 1995, Archives of biochemistry and biophysics.

In vitroα1‐adrenoceptor pharmacology of Ro 70–0004 and RS‐100329, novel α1A‐adrenoceptor selective antagonists

J. Gever, A. Ford, D. V. Daniels, 1999 .

Improved methodology for the enantiospecific synthesis of polyunsaturated phospholipids13

C. Ramesha, F. Talamas, D. Morgans, 1994 .

Discovery of Tirasemtiv, the First Direct Fast Skeletal Muscle Troponin Activator

D. Hwee, K. Leung, B. Morgan, 2018, ACS medicinal chemistry letters.

Fast Skeletal Muscle Troponin Activator tirasemtiv Increases Muscle Function and Performance in the B6SJL-SOD1G93A ALS Mouse Model

J. Jasper, D. Hwee, Z. Jia, 2014, PloS one.

Stereospecific functionalization of (R)-(−)-1,1′-bi-2-naphthol triflate

T. Ward, L. J. Kurz, D. Morgans, 1990 .

An investigation of the palladium-catalyzed, formate-mediated hydroxycarbonylation of optically active 1-arylethyl esters

D. Morgans, J. Kern, Gary R. Lee, 1991 .

The Florisil® catalyzed [1,3]-sigmatropic shift of allyl phenyl ethers — An entryway into novel mycophenolic acid analogues

F. Talamas, S. Cutler, D. B. Smith, 1997 .

On the utility of α-heteroatom substituted orthoesters in the Johnson Claisen rearrangement☆

W. Palmer, D. B. Smith, D. Morgans, 1994 .

Synthesis, pharmacology and pharmacokinetics of 3-(4-aryl-piperazin-1-ylalkyl)-uracils as uroselective alpha1A-antagonists.

A. Ford, T. Williams, J. Jasper, 2003, Bioorganic & medicinal chemistry letters.

Epoxy alcohol rearrangements: hydroxyl-mediated delivery of Lewis acid promoters

D. Morgans, K. B. Sharpless, S. G. Traynor, 1981 .

An intramolecular diels-alder approach to the galanthan ring system

D. Morgans, G. Stork, 1979 .

N-3-ALKYLATION OF URACIL AND DERIVATIVES VIA N-1-BOC PROTECTION

A. Zamilpa, Á. Guzmán, S. Jaime-Figueroa, 2001 .

Epoxy alcohol rearrangements: hydroxyl-mediated delivery of Lewis acid promoters

D. Morgans, K. B. Sharpless, S. G. Traynor, 1981 .

Alkylglycidic acids: potential new hypoglycemic agents.

D. Morgans, G. Tutwiler, W. Ho, 1986, Journal of medicinal chemistry.

Synthesis and Pharmacology of 3-(4-Arylpiperazin-1-ylalkyl)-Uracils as Uroselective α 1A -Antagonists

A. Ford, T. Williams, J. Jasper, 2003 .

Synthesis of N-allylhydroxamic acids via [3,3]-sigmatropic rearrangement☆

Alejandra Trejo, F. Talamas, D. B. Smith, 1994 .

Effective killing of the human pathogen Candida albicans by a specific inhibitor of non-essential mitotic kinesin Kip1p

M. Maxon, D. Roof, R. Sakowicz, 2007, Molecular microbiology.

Antitumor activity of an allosteric inhibitor of centromere-associated protein-E

Neysa Nevins, W. D. Cornwell, R. Annan, 2010, Proceedings of the National Academy of Sciences.

Discovery of Reldesemtiv, a Fast Skeletal Muscle Troponin Activator for the Treatment of Impaired Muscle Function.

D. Hwee, B. Morgan, J. Hartman, 2021, Journal of medicinal chemistry.

A Novel Fast Skeletal Muscle Activator, CK‐2017357, Improves Muscle Function in a Rodent Model of Myasthenia Gravis

B. Morgan, J. Hartman, A. Russell, 2011 .

Thrombocytopenia and Platelet Functional Defects in Pre-Eclampsia: Implications for Regional Anaesthesia

S. Gatt, D. Morgans, P. Isert, 1990, Anaesthesia and intensive care.

Novel inhibitors of poly(ADP-ribose) polymerase/PARP1 and PARP2 identified using a cell-based screen in yeast.

K Jarnagin, K. Jarnagin, S. Tugendreich, 2001, Cancer research.

Activation of fast skeletal muscle troponin as a potential therapeutic approach for treating neuromuscular diseases

D. Claflin, B. Morgan, J. Hartman, 2011, Nature Medicine.

Asymmetric Synthesis and Stereochemical Assignment of RS-97613, a Potent Immunosuppressive and Antiinflammatory Agent†

A. Link, D. B. Smith, D. Morgans, 1996 .

DIRECT N3 ALKYLATION OF URACIL AND DERIVATIVES VIA N1-2-(TRIMETHYLSILYL)ETHOXYMETHYL PROTECTION

Á. Guzmán, S. Jaime-Figueroa, D. Morgans, 1997 .

Direct N3 Alkylation of Uracil and Derivatives via N1‐[2‐(Trimethylsilyl)ethoxymethyl] Protection.

Á. Guzmán, S. Jaime-Figueroa, D. Morgans, 1998 .

Tirasemtiv amplifies skeletal muscle response to nerve activation in humans

R. Enoka, S. Baudry, A. Wolff, 2014, Muscle & nerve.

Cardiac Myosin Activation: A Potential Therapeutic Approach for Systolic Heart Failure

D. Cox, D. Kass, S. Vatner, 2011, Science.

In Vitro and In Vivo Characterization of CK-1827452, a Selective Cardiac Myosin Activator

R. Sakowicz, Guillermo L. Godinez, D. Morgans, 2006 .

Thrombocytopenia and Platelet Functional Defects in Pre-Eclampsia: Implications for Regional Anesthesia

S. Gatt, D. Morgans, P. Isert, 1991 .

In vitro alpha1-adrenoceptor pharmacology of Ro 70-0004 and RS-100329, novel alpha1A-adrenoceptor selective antagonists.

J. Gever, A. Ford, R. Chess-Williams, 1999, British Journal of Pharmacology.

Inhibition of Smooth Muscle Myosin as a Novel Therapeutic Target for Hypertension

S. Vatner, P. Abarzúa, Z. Jia, 2011, Journal of Pharmacology and Experimental Therapeutics.

Temporary serine protection in solid phase synthesis of LH-RH analogs.

H. Arzeno, W. Bingenheimer, D. Morgans, 2009, International journal of peptide and protein research.

A Simple, Efficient Synthesis of N6-[bis(ethylamino) methylene]-N2-[(1,1-dimethylethoxy)carbonyl]-lysine (Boc-diethylhomoarginine)

H. Arzeno, W. Bingenheimer, D. Morgans, 1990 .

A Simple, Efficient Synthesis of N6-(Bis(ethylamino)methylene)-N2-((1, 1-dimethylethoxy)carbonyl)lysine (Boc-diethylhomoarginine).

H. Arzeno, W. Bingenheimer, D. Morgans, 1991 .

Addition of lithio-.alpha.-thiophenyl nitriles to aldehydes and ketones

D. Morgans, G. Feigelson, 1982 .

Novel approach to vicinal stereocontrol during carbon-carbon bond formation. Stereocontrolled synthesis of (.+-.)-threo-juvabione

D. Morgans, G. Feigelson, 1983 .

N-arylpiperazinyl-N'-propylamino derivatives of heteroaryl amides as functional uroselective alpha 1-adrenoceptor antagonists.

A. Ford, T. Williams, M. S. Kava, 1997, Journal of medicinal chemistry.

A CONGENER STUDY OF ZILEUTON REVEALS INTERESTING EFFECTS ON GLUCURONIDATION RATES

Á. Guzmán, J. Muchowski, A. Kluge, 1994 .

The structural mechanism of human glycogen synthesis by the GYS1-GYG1 complex.

N. Fastman, A. Depaoli-Roach, P. Roach, 2022, Cell reports.

Antitumor activity of an allosteric inhibitor of centromere-associated protein-E

Neysa Nevins, W. D. Cornwell, R. Annan, 2010, Proceedings of the National Academy of Sciences.