C. Watson

发表

Recent progress in discovery of small-molecule CCR5 chemokine receptor ligands as HIV-1 inhibitors.

Terry Kenakin, Hanbiao Yang, T. Kenakin, 2003, Bioorganic & medicinal chemistry.

Determining the Potency and Molecular Mechanism of Action of Insurmountable Antagonists

T. Kenakin, S. Jenkinson, C. Watson, 2006, Journal of Pharmacology and Experimental Therapeutics.

CCR5 chemokine receptors: gatekeepers of HIV-1 infection.

T. Kenakin, W. Kazmierski, L. Boone, 2002, Current drug targets. Infectious disorders.

Discovery of bioavailable 4,4-disubstituted piperidines as potent ligands of the chemokine receptor 5 and inhibitors of the human immunodeficiency virus-1.

Brian A. Chauder, W. Kazmierski, D. K. Jones-Hertzog, 2008, Journal of medicinal chemistry.

Constitutive receptor systems for drug discovery.

J. Way, W. J. Chen, D. Ignar, 1999, Journal of pharmacological and toxicological methods.

Recent Progress in Discovery of Small‐Molecule CCR5 Chemokine Receptor Ligands as HIV‐1 Inhibitors

T. Kenakin, W. Kazmierski, F. Deanda, 2003 .

A simple method for quantifying functional selectivity and agonist bias.

Arthur Christopoulos, Steven J Novick, Steven J. Novick, 2012, ACS chemical neuroscience.

Pharmacological Applications of Baculovirus‐Mediated Protein Expression in Mammalian Cells

J. P. Condreay, C. Watson, C. A. Watson, 2010, Current protocols in pharmacology.

Novel 4,4-disubstituted piperidine-based C-C chemokine receptor-5 inhibitors with high potency against human immunodeficiency virus-1 and an improved human ether-a-go-go related gene (hERG) profile.

Brian A. Chauder, W. Kazmierski, B. Chauder, 2011, Journal of medicinal chemistry.

Use of constitutive G protein-coupled receptor activity for drug discovery.

J. Way, W. J. Chen, C. Jayawickreme, 2000, Molecular pharmacology.

Recombinant human CXC-chemokine receptor-4 in melanophores are linked to Gi protein: seven transmembrane coreceptors for human immunodeficiency virus entry into cells.

W. J. Chen, C. Jayawickreme, W. Dallas, 1998, Molecular pharmacology.

[2-(4-Phenyl-4-piperidinyl)ethyl]amine based CCR5 antagonists: derivatizations at the N-terminal of the piperidine ring.

T. Kenakin, W. Kazmierski, R. Ferris, 2009, Bioorganic & medicinal chemistry letters.

The CCR5 Receptor-Based Mechanism of Action of 873140, a Potent Allosteric Noncompetitive HIV Entry Inhibitor

T. Kenakin, W. Kazmierski, S. Jenkinson, 2005, Molecular Pharmacology.

The use of stimulus-biased assay systems to detect agonist-specific receptor active states: implications for the trafficking of receptor stimulus by agonists.

T. Kenakin, P. Irving, J. Way, 2000, Molecular pharmacology.

Corrigendum to “Recent Progress in Discovery of Small–Molecule CCR5 Chemokine Receptor Ligands as HIV-1 Inhibitors” [Bioorg. Med. Chem. 2003, 11, 2663–2676]

T. Kenakin, W. Kazmierski, F. Deanda, 2003 .

Expression cloning and receptor pharmacology of human calcitonin receptors from MCF-7 cells and their relationship to amylin receptors.

K. Beaumont, P. Irving, J. Way, 1997, Molecular pharmacology.

Functional Screening in the Melanophore Bioassay

T. Kenakin, C. Jayawickreme, David L Moncol, 2005, Current Protocols in Pharmacology.