L. Gerlach

发表

Inhibition of Human Immunodeficiency Virus Replication by a Dual CCR5/CXCR4 Antagonist

Dominique Schols, E. De Clercq, T. Schwartz, 2004, Journal of Virology.

Model-Based Discovery of Synthetic Agonists for the Zn2+-Sensing G-Protein-Coupled Receptor 39 (GPR39) Reveals Novel Biological Functions.

T. Schwartz, T. Frimurer, B. Holst, 2017, Journal of medicinal chemistry.

Metal Ion Site Engineering Indicates a Global Toggle Switch Model for Seven-transmembrane Receptor Activation*

T. Schwartz, T. Frimurer, B. Holst, 2006, Journal of Biological Chemistry.

GPR39 signaling is stimulated by zinc ions but not by obestatin.

T. Schwartz, B. Holst, Kristoffer L Egerod, 2007, Endocrinology.

Identification of Indole Derivatives Exclusively Interfering with a G Protein-Independent Signaling Pathway of the Prostaglandin D2 Receptor CRTH2

J. M. Mathiesen, E. Kostenis, T. Ulven, 2005, Molecular Pharmacology.

Molecular Interactions of Cyclam and Bicyclam Non-peptide Antagonists with the CXCR4 Chemokine Receptor*

T. Schwartz, G. Bridger, G J Bridger, 2001, The Journal of Biological Chemistry.

Molecular Mechanism of Action of Monocyclam Versus Bicyclam Non-peptide Antagonists in the CXCR4 Chemokine Receptor*

Dominique Schols, T. Schwartz, M. Rosenkilde, 2007, Journal of Biological Chemistry.

Metal ion enhanced binding of AMD3100 to Asp262 in the CXCR4 receptor.

Kasper P. Jensen, T. Schwartz, J. S. Jakobsen, 2003, Biochemistry.

A physicogenetic method to assign ligand-binding relationships between 7TM receptors.

Evi Kostenis, Thomas M Frimurer, Trond Ulven, 2005, Bioorganic & medicinal chemistry letters.

Novel selective orally active CRTH2 antagonists for allergic inflammation developed from in silico derived hits.

Evi Kostenis, Thomas M Frimurer, Trond Ulven, 2006, Journal of medicinal chemistry.

Preparation and evaluation of sulfur-containing metal chelators.

J. Bergman, T. Högberg, L. Gerlach, 2003, Organic & biomolecular chemistry.

Inhibition of demethylases by GSK-J1/J4

Kristian Helin, Thomas Boesen, K. Helin, 2014, Nature.

HER2-positive breast-cancer cell lines are sensitive to KDM5 inhibition: definition of a gene-expression model for the selection of sensitive cases

R. Neve, K. Helin, P. Ubezio, 2018, Oncogene.

Molecular Mechanism of AMD3100 Antagonism in the CXCR4 Receptor

Mette M. Rosenkilde, T. Schwartz, M. Rosenkilde, 2004, Journal of Biological Chemistry.

Inhibition of Human Immunodeficiency Virus Replication by a Dual CCR 5 / CXCR 4 Antagonist

Erik De Clercq, Dominique Schols, T. Schwartz, 2004 .

Mutations at the CXCR4 interaction sites for AMD3100 influence anti‐CXCR4 antibody binding and HIV‐1 entry

Dominique Schols, E. De Clercq, T. Schwartz, 2003, FEBS letters.

Arylamide derivatives as allosteric inhibitors of the integrin α2β1/type I collagen interaction

W. DeGrado, H. Yin, G. Vilaire, 2006 .

Arylamide derivatives as allosteric inhibitors of the integrin alpha2beta1/type I collagen interaction.

W. DeGrado, H. Yin, G. Vilaire, 2006, Bioorganic & medicinal chemistry letters.

Kruidenier et al. reply

K. Helin, M. Labelle, T. Boesen, 2014, Nature.

Long-acting lipidated analogue of human pancreatic polypeptide is slowly released into circulation.

T. Schwartz, B. Holst, C. Elling, 2011, Journal of medicinal chemistry.

Mutation of Asp(171) and Asp(262) of the chemokine receptor CXCR4 impairs its coreceptor function for human immunodeficiency virus-1 entry and abrogates the antagonistic activity of AMD3100.

E. De Clercq, T. Schwartz, E. Clercq, 2001, Molecular pharmacology.

The growth hormone-releasing hormone receptor: desensitisation following short-term agonist exposure.

C. Foged, B. S. Hansen, P. H. Andersen, 2001, Acta Pharmacologica et Toxicologica.