Zitai Sang

发表

Exploratory Process Development and Kilogram-Scale Synthesis of a Novel Oxazolidinone Antibacterial Candidate

Tao Yang, Youfu Luo, Jiaxuan Chen, 2014 .

Discovery of novel bis-oxazolidinone compounds as potential potent and selective antitubercular agents.

Yuquan Wei, Tao Yang, Youfu Luo, 2014, Bioorganic & medicinal chemistry letters.

Synthesis and antibacterial activity evaluation of C-5 side chain modified analogues of FYL-66, a potential agent against methicillin-resistant Staphylococcus aureus

Tao Yang, Youfu Luo, Haiyue Long, 2015 .

Efficient discovery of novel antimicrobials through integration of synthesis and testing in crude ribosome extract.

Yuanzheng Zhou, Tao Yang, Youfu Luo, 2019, Chemical communications.

Discovery of novel peptidomimetic boronate ClpP inhibitors with noncanonical enzyme mechanism as potent virulence blockers in vitro and in vivo.

Yang Yang, Yuanzheng Zhou, Tao Yang, 2020, Journal of Medicinal Chemistry.

Biodegradable nanoassemblies of piperlongumine display enhanced anti-angiogenesis and anti-tumor activities.

Yuquan Wei, C. Gong, Chao Yang, 2014, Nanoscale.

Design, synthesis, and biological evaluation of quinazoline derivatives as dual HDAC1 and HDAC6 inhibitors for the treatment of cancer

Linhong He, Jinying Chen, Zitai Sang, 2018, Chemical biology & drug design.

Discovery of napabucasin derivatives for the treatment of tuberculosis.

Tianyu Zhang, Yang Yang, Tao Yang, 2019, MedChemComm.

Discovery of a Teraryl Oxazolidinone Compound (S)-N-((3-(3-Fluoro-4-(4-(pyridin-2-yl)-1H-pyrazol-1-yl)phenyl)-2-oxooxazolidin-5-yl)methyl)acetamide Phosphate as a Novel Antimicrobial Agent with Enhanced Safety Profile and Efficacies.

Yuquan Wei, Sheng-yong Yang, Tao Yang, 2015, Journal of medicinal chemistry.

Discovery of novel anti-tuberculosis agents with pyrrolo[1,2-a]quinoxaline-based scaffold.

Tianyu Zhang, Yang Yang, Tao Yang, 2018, Bioorganic & medicinal chemistry letters.

Natural amino acid salt catalyzed aldol reactions of isatins with ketones: highly enantioselective construction of 3-alkyl-3-hydroxyindolin-2-ones

Tao Yang, Youfu Luo, Zicheng Li, 2015 .

Design and synthesis of novel pyrimidine derivatives as potent antitubercular agents.

Tianyu Zhang, Yang Yang, Tao Yang, 2019, European journal of medicinal chemistry.

Discovery of hybrids of indolin-2-one and nitroimidazole as potent inhibitors against drug-resistant bacteria

Gu He, Yang Yang, Yuanzheng Zhou, 2018, The Journal of Antibiotics.

Inclusion complex of magnolol with hydroxypropyl-β-cyclodextrin: characterization, solubility, stability and cell viability

Xuebing Li, Tao Yang, Neng Qiu, 2016, Journal of Inclusion Phenomena and Macrocyclic Chemistry.

The in vivo and in vitro phase I metabolism of FYL-67, a novel oxazolidinone antibacterial drug, studied by LC-MS/MS.

Tao Yang, Youfu Luo, Haiyue Long, 2016, Drug testing and analysis.

A novel series of napabucasin derivatives as orally active inhibitors of signal transducer and activator of transcription 3 (STAT3).

A. Tong, Yang Yang, Tao Yang, 2019, European journal of medicinal chemistry.

Improving the pharmacokinetics and tissue distribution of pyrinezolid by self-assembled polymeric micelles.

Lan Mei, G. Guo, Xiaoling Li, 2017, Colloids and surfaces. B, Biointerfaces.

Discovery of 5-methyl-2-(4-((4-(methylsulfonyl)benzyl)oxy)phenyl)-4-(piperazin-1-yl)pyrimidine derivatives as novel GRP119 agonists for the treatment of diabetes and obesity

Liang Ma, Linhong He, Jinying Chen, 2017, Molecular Diversity.

Design, synthesis and biological evaluation of novel pyrrole derivatives as potential ClpP1P2 inhibitor against Mycobacterium tuberculosis.

Lijuan Chen, Tianyu Zhang, Yang Yang, 2018, Bioorganic chemistry.