F. Fabis

发表

Synthesis of ortho-substituted cyanopyridines through lithio intermediate trapping

S. Rault, A. Bouillon, T. Cailly, 2005 .

Synthesis and characterization of a iodine-125-labeled pyrrolo[1,2-a]thieno[3,2-e]pyrazine and evaluation as a potential 5-HT4R SPECT tracer.

Y. Charnay, S. Rault, P. Millet, 2010, European journal of medicinal chemistry.

Small-Animal Single-Photon Emission Computed Tomographic Imaging of the Brain Serotoninergic Systems in Wild-Type and Mdrla Knockout Rats

N. Ginovart, Y. Charnay, S. Rault, 2014, Molecular imaging.

TSPO and amyloid deposits in sub-regions of the hippocampus in the 3xTgAD mouse model of Alzheimer’s disease

M. Grégoire, P. Millet, E. Kövari, 2019, Neurobiology of Disease.

Phe369(7.38) at human 5‐HT7 receptors confers interspecies selectivity to antagonists and partial agonists

J. Åqvist, M. Loza, H. Gutiérrez‐de‐Terán, 2010, British journal of pharmacology.

Phenylpyrroles, a new chemolibrary virtual screening class of 5-HT7 receptor ligands.

H. Vaudry, S. Rault, Magalie Paillet-Loilier, 2005, Bioorganic & medicinal chemistry letters.

Efficient synthesis of N1- or N3-substituted thieno[2,3-d]imidazol-2-ones

S. Rault, F. Fabis, S. Jolivet-Fouchet, 1999 .

Thiaisatoic anhydrides: Efficient synthesis under microwave heating conditions and study of their reactivity

S. Rault, F. Fabis, M. Robba, 1998 .

Chronic activation of 5-HT4 receptors or blockade of 5-HT6 receptors improve memory performances

V. Bouet, T. Freret, M. Boulouard, 2015, Behavioural Brain Research.

Synthesis and Structure-Affinity Relationships of Selective High- Affinity 5-HT4 Receptor Antagonists: Application to the Design of New Potential Single Photon Emission Computed Tomography (SPECT) Tracers

Y. Charnay, D. Caignard, S. Rault, 2012 .

Thiofunctionalization of Electron‐Rich Heteroarenes through Magnesiation and Trapping with Octasulfur

T. Cailly, F. Fabis, V. Collot, 2021, Advanced Synthesis & Catalysis.

Two-step synthesis of substituted 3-aminoindazoles from 2-bromobenzonitriles.

S. Rault, T. Cailly, F. Fabis, 2010, The Journal of organic chemistry.

Iodoindazoles with Selective Magnesiation at Position 3: A Route to Highly Functionalized Indazoles.

T. Cailly, F. Fabis, C. Fossey, 2016, Chemistry.

Synthesis and evaluation of novel serotonin 4 receptor radiotracers for single photon emission computed tomography.

S. Corvaisier, P. Millet, Céline Ballandonne, 2016, European journal of medicinal chemistry.

Controlled Access to C 1 ‐Symmetrical Cyclotriveratrylenes (CTVs) by Using a Sequential Barluenga Boronic Coupling (BBC) Approach

T. Cailly, F. Fabis, E. Dubost, 2021, Advanced Synthesis & Catalysis.

Synthesis and structure-affinity relationships of selective high-affinity 5-HT(4) receptor antagonists: application to the design of new potential single photon emission computed tomography tracers.

Y. Charnay, D. Caignard, S. Rault, 2012, Journal of medicinal chemistry.

Straightforward access to ethyl 3-aminofuropyridine-2-carboxylates from 1-chloro-2-cyano-or 1 -hydroxy -2 -cyano -substituted pyridines

S. Rault, T. Cailly, F. Fabis, 2007 .

N-tosylcarboxamide as a transformable directing group for Pd-catalyzed C-H ortho-arylation.

T. Cailly, F. Fabis, C. Fossey, 2012, Organic letters.

General method for the synthesis of substituted phenanthridin-6(5H)-ones using a KOH-mediated anionic ring closure as the key step

S. Rault, Rémi Legay, T. Cailly, 2010 .

Straightforward Access to Ethyl 3‐Aminofuropyridine‐2‐carboxylates from 1‐Chloro‐2‐cyano‐ or 1‐Hydroxy‐2‐cyano‐Substituted Pyridines.

S. Rault, T. Cailly, F. Fabis, 2008 .

Efficient Room‐Temperature One‐Pot Synthesis of 2‐Amino‐3‐alkyl(3‐aryl)quinazolin‐4(3H)‐ones

S. Rault, F. Fabis, C. Fossey, 2011 .

Synthesis of new 8-arylisoquinoline derivatives by application of palladium-catalyzed Suzuki cross-coupling reactions

S. Rault, F. Fabis, D. Cortes, 2005 .

A general synthesis of diversely substituted indazoles and hetero-aromatic derivatives from o-halo-(het)arylaldehydes or -phenones

T. Cailly, F. Fabis, V. Collot, 2014 .

Novel Rearrangement of Pyrrolo[2,1-c][1,4]benzodiazepines into Pyrrolo[2,1-b]quinazolinones, Analogous of Alkaloid, Vasicinone

S. Rault, P. Ochsenbein, F. Fabis, 1999 .

Synthesis of new pyrrolo[2,1-b]quinazolinones by original rearrangement of pyrrolo[2,1-c][1,4]benzodiazepines

S. Rault, P. Ochsenbein, F. Fabis, 1998 .

Synthesis and biological evaluation as AChE inhibitors of new indanones and thiaindanones related to donepezil.

Jana Sopkova-de Oliveira Santos, S. Rault, F. Dauphin, 2005, European journal of medicinal chemistry.

FIRST SYNTHESIS OF 4-AMINO-4,5-DIHYDRO-1-PHENYLCYCLOPENTA[ b]PYRROL-6(1H)-ONES

S. Rault, P. Dallemagne, F. Fabis, 1994 .

Selective ortho-bromination of substituted benzaldoximes using Pd-catalyzed C-H activation: application to the synthesis of substituted 2-bromobenzaldehydes.

S. Rault, T. Cailly, F. Fabis, 2011, The Journal of organic chemistry.

A convenient microwave-assisted 5-amination of flavones

S. Rault, F. Fabis, F. Lefoulon, 2008 .

Synthesis of New 8-Arylisoquinoline Derivatives by Application of Palladium-Catalyzed Suzuki Cross-Coupling Reactions.

S. Rault, F. Fabis, D. Cortes, 2005 .

Cyclopropyl‐tryptamine Analogues: Synthesis and Biological Evaluation as 5‐HT6 Receptor Ligands

S. Rault, Stéphane Gérard, J. Sapi, 2013, ChemMedChem.

A new, direct, and efficient synthesis of benzonaphthyridin-5-ones

S. Rault, T. Cailly, F. Fabis, 2006 .

An expedient route to aromatic pyrrolo[2,1-c][1,4]benzodiazepines and a study of their reactivity

Jana Sopkova-de Oliveira Santos, S. Rault, F. Fabis, 2001 .

General Method for the Synthesis of Substituted Phenanthridin‐6(5H)‐ones Using a KOH‐Mediated Anionic Ring Closure as the Key Step.

S. Rault, Rémi Legay, T. Cailly, 2010 .

The synthesis of three new heterocycles: the pyrido[4,3 or 3,4 or 2,3-c]-1,5-naphthyridines

S. Rault, Rémi Legay, H. Oulyadi, 2007 .

A NEW EFFICIENT SYNTHESIS OF 3-AMINO-1-PHENYLPYRROLE

S. Rault, P. Dallemagne, F. Fabis, 1995 .

Room-temperature ortho-alkoxylation and -halogenation of N-tosylbenzamides by using palladium(II)-catalyzed C-H activation.

J. Sopková-de Oliveira Santos, T. Cailly, F. Fabis, 2014, Chemistry.

Synthesis of New Aromatic Pyrrolo[2,1- c] [1,4]benzodiazepines and Pyrrolo[1,2- a] thieno[3,2- e] [1,4]diazepines as Anti-tumoral Agents

P. Renard, S. Rault, V. Lisowski, 2002, Journal of enzyme inhibition and medicinal chemistry.

A Convenient Rearrangement of 1-Phenylpyrrole-2-carboxaldehydes into Their 3-Isomers

S. Rault, P. Dallemagne, F. Fabis, 1994 .

Design of fluorinated 5-HT(4)R antagonists: influence of the basicity and lipophilicity toward the 5-HT(4)R binding affinities.

T. Cailly, F. Fabis, B. Linclau, 2013, Bioorganic & medicinal chemistry.

Synthesis and combinatorial approach of the reactivity of 6- and 7-arylthieno[3,2-d][1,3]oxazine-2,4-diones

S. Rault, J. Lancelot, Emmanuelle Braud, 2003 .

A biotin-conjugated pyridine-based isatoic anhydride, a selective room temperature RNA-acylating agent for the nucleic acid separation.

A. Laayoun, T. Cailly, F. Fabis, 2015, Organic & biomolecular chemistry.

Biotin-conjugated N-methylisatoic anhydride: a chemical tool for nucleic acid separation by selective 2'-hydroxyl acylation of RNA.

A. Laayoun, T. Cailly, F. Fabis, 2014, Chemical communications.

Synthesis of Substituted Diazino[c]quinolin-5(6H)-ones, Diazino[c]isoquinolin-6(5H)-ones, Diazino[c]naphthyridin-6(5H)-ones and Diazino[c]naphthyridin-5(6H)-ones

T. Cailly, F. Fabis, J. Bouillon, 2013 .

Design of iodinated radioligands for SPECT imaging of central human 5-HT4R using a ligand lipophilicity efficiency approach.

P. Millet, T. Cailly, F. Fabis, 2020, Bioorganic chemistry.

Design of a serotonin 4 receptor radiotracer with decreased lipophilicity for single photon emission computed tomography.

Y. Charnay, Aurélien Lesnard, P. Millet, 2015, European journal of medicinal chemistry.

Solution-phase parallel synthesis of a 1140-member ureidothiophene carboxylic acid library.

S. Rault, J. Lancelot, Emmanuelle Braud, 2005, Journal of combinatorial chemistry.

Thiaisatoic Anhydrides: Efficient Synthesis under Microwave Heating Conditions and Study of Their Reactivity.

S. Rault, F. Fabis, M. Robba, 1998 .

First direct synthesis of pyrrolo[1,2-a]thieno[3,2-e]- or [2,3-e][1,4]diazepines, thiophene analogues of pyrrolo[2,1-c][1,4]benzodiazepines

S. Rault, F. Fabis, S. Jolivet-Fouchet, 1998 .

Virtual Screening Discovery of New Acetylcholinesterase Inhibitors Issued from CERMN Chemical Library

Jana Sopkova-de Oliveira Santos, Aurélien Lesnard, Jean-Hugues Agondanou, 2010, J. Chem. Inf. Model..

Pharmacomodulation of a Sulfamide 5-HT6 Receptor Ligand

S. Rault, F. Dauphin, P. Uriac, 2004, Journal of enzyme inhibition and medicinal chemistry.

Base-Mediated Radio-Iodination of Arenes by using Organosilane and Organogermane as Radiolabelling Precursors.

T. Cailly, F. Fabis, A. Dahiya, 2023, Chemistry.

A General Synthesis of Diversely Substituted Indazoles and Hetero-Aromatic Derivatives from O-Halo-(het)arylaldehydes or -phenones.

T. Cailly, F. Fabis, V. Collot, 2015 .

Molecular Modeling Studies Focused on 5-HT7 versus 5-HT1A Selectivity. Discovery of Novel Phenylpyrrole Derivatives with High Affinity for 5-HT7 Receptors

Aurélien Lesnard, Frédéric Fabis, Ronan Bureau, 2005, J. Chem. Inf. Model..

Rearrangement of pyrrolo[2,1-c][1,4]benzodiazepines into cyclopenta[b][1,4]benzodiazepines under microwave or conventional heating conditions

S. Rault, F. Fabis, S. Jolivet-Fouchet, 1997 .

Novel aminoethylbiphenyls as 5-HT7 receptor ligands.

H. Vaudry, Aurélien Lesnard, S. Rault, 2007, Bioorganic & medicinal chemistry letters.

Reactive astrocytes mediate TSPO overexpression in response to sustained CNTF exposure in the rat striatum

V. Garibotto, C. Escartin, T. Cailly, 2023, Molecular Brain.

Low-dose brain irradiation normalizes TSPO and CLUSTERIN levels and promotes the non-amyloidogenic pathway in pre-symptomatic TgF344-AD rats

G. Frisoni, V. Garibotto, T. Zilli, 2022, Journal of neuroinflammation.

Small-animal single-photon emission computed tomographic imaging of the brain serotoninergic systems in wild-type and mdr1a knockout rats.

N. Ginovart, Y. Charnay, S. Rault, 2014, Molecular imaging.

Improvements of C–H Radio-Iodination of N-Acylsulfonamides toward Implementation in Clinics

T. Cailly, F. Fabis, J. Bouillon, 2019, Synthesis.

Palladium-Mediated Site-Selective C-H Radio-iodination.

P. Barbey, G. Pieters, T. Cailly, 2018, Organic Letters.

Alterations in dopamine system and in its connectivity with serotonin in a rat model of Alzheimer’s disease

P. Millet, T. Cailly, F. Fabis, 2021, Brain communications.