Cara E. Brocklehurst

发表

Synthesis of Bicyclo[1.1.1]pentane Bioisosteres of Internal Alkynes and para-Disubstituted Benzenes from [1.1.1]Propellane.

I. S. Makarov, P. Knochel, G. Koch, 2017, Angewandte Chemie.

Nitration Chemistry in Continuous Flow using Fuming Nitric Acid in a Commercially Available Flow Reactor

Cara E. Brocklehurst, Hansjörg Lehmann, Luigi La Vecchia, 2011 .

Small-molecule WNK inhibition regulates cardiovascular and renal function.

Y. Yagi, P. Hoffmann, Mitsunori Kato, 2016, Nature chemical biology.

Integrated and Automated High-Throughput Purification of Libraries on Microscale.

Jonathan E. Grob, T. Wagner, J. Reilly, 2022, SLAS technology.

Development of autotaxin inhibitors: A series of zinc binding triazoles.

M. Dowling, M. Faller, E. Hardaker, 2018, Bioorganic & medicinal chemistry letters.

Microtiter Plate (MTP) Reaction Screening and Optimization of Surfactant Chemistry: Examples of Suzuki–Miyaura and Buchwald–Hartwig Cross-Couplings in Water

F. Gallou, J. C. D. Hartwieg, Cara E. Brocklehurst, 2018, Organic Process Research & Development.

Functionalization of 1,3,4-Oxadiazoles and 1,2,4-Triazoles via Selective Zincation or Magnesiation Using 2,2,6,6-Tetramethylpiperidyl Bases.

P. Knochel, Cara E. Brocklehurst, Kuno Schwärzer, 2020, Organic letters.

Improving Nonspecific Binding and Solubility: Bicycloalkyl Groups and Cubanes as para‐Phenyl Bioisosteres

Thomas C. Fessard, E. Briard, Y. Auberson, 2017, ChemMedChem.

Benzyl N‐[(Benzyloxy)methyl]carbamate: An Improved Aminomethylation Electrophile for the Synthesis of (Benzyloxy)carbonyl (Cbz)‐Protected Chiral β2‐Amino Acids

Cara E. Brocklehurst, L. Vecchia, Flavio Ossola, 2010 .

In Situ Preparation and Consumption of O-Mesitylsulfonylhydroxylamine (MSH) in Continuous Flow for the Amination of Pyridines

G. Koch, Cara E. Brocklehurst, L. La Vecchia, 2017, Synlett.

Discovery of Icenticaftor (QBW251), a Cystic Fibrosis Transmembrane Conductance Regulator Potentiator with Clinical Efficacy in Cystic Fibrosis and Chronic Obstructive Pulmonary Disease.

Paul J. Groot-Kormelink, D. Rowlands, H. Danahay, 2021, Journal of medicinal chemistry.

Diastereoisomeric Salt Formation and Enzyme-Catalyzed Kinetic Resolution as Complementary Methods for the Chiral Separation of cis-/trans-Enantiomers of 3-Aminocyclohexanol

Cara E. Brocklehurst, L. Vecchia, M. Vögtle, 2011 .

Fostering Research Synergies between Chemists in Swiss Academia and at Novartis.

Lucie E. Lovelle, Y. Auberson, Radka Snajdrova, 2021, Chimia.

Optimization of a Class of Dihydrobenzofurane Analogs toward Orally Efficacious YAP‐TEAD Protein‐Protein Interaction Inhibitors

P. Furet, P. Chène, T. Schmelzle, 2023, ChemMedChem.

Selective functionalization of the 1H-imidazo[1,2-b]pyrazole scaffold. A new potential non-classical isostere of indole and a precursor of push–pull dyes

T. Bein, S. Rout, P. Knochel, 2021, Chemical science.

MicroCycle: An Integrated and Automated Platform to Accelerate Drug Discovery.

Cara E. Brocklehurst, Richard I. Robinson, P. Ertl, 2024, Journal of medicinal chemistry.