T. Kvist

发表

Structure–Activity Relationships for Negative Allosteric mGluR5 Modulators

Christina Mølck, Hans Bräuner-Osborne, Kasper Harpsøe, 2012, ChemMedChem.

1,2,3-triazolyl amino acids as AMPA receptor ligands.

J. M. Mathiesen, D. S. Pedersen, A. Abell, 2010, Bioorganic & medicinal chemistry letters.

Implementation of a Fluorescence-Based Screening Assay Identifies Histamine H3 Receptor Antagonists Clobenpropit and Iodophenpropit as Subunit-Selective N-Methyl-d-Aspartate Receptor Antagonists

J. Snyder, Yuhong Du, S. Traynelis, 2010, Journal of Pharmacology and Experimental Therapeutics.

The use of Xenopus oocytes in drug screening

K. Hansen, H. Bräuner‐Osborne, T. Kvist, 2011, Expert opinion on drug discovery.

The four human gamma-aminobutyric acid (GABA) transporters: pharmacological characterization and validation of a highly efficient screening assay.

H. Bräuner‐Osborne, T. Kvist, B. Christiansen, 2009, Combinatorial chemistry & high throughput screening.

Implementation of a fluorescence-based screening assay identifies histamine H 3 receptor antagonists clobenpropit and iodophenpropit as subunit-selective NMDA receptor antagonists

J. Snyder, Yuhong Du, Katie M Vance, 2010 .

Discovery of a subtype selective inhibitor of the human betaine/GABA transporter 1 (BGT-1) with a non-competitive pharmacological profile.

A. Schousboe, R. Clausen, H. Bräuner‐Osborne, 2013, Biochemical Pharmacology.

Semaglutide improves postprandial glucose and lipid metabolism, and delays first‐hour gastric emptying in subjects with obesity

J. Blundell, A. Flint, T. Kvist, 2017, Diabetes, obesity & metabolism.

(1S, 3S)-3-amino-4-difluoromethylenyl-1-cyclopentanoic acid (CPP-115), a potent γ-aminobutyric acid aminotransferase inactivator for the treatment of cocaine addiction.

J. Brodie, A. Schousboe, C. Craft, 2012, Journal of medicinal chemistry.

Structure-based discovery of antagonists for GluN3-containing N-methyl-d-aspartate receptors

J. Greenwood, S. Traynelis, K. Hansen, 2013, Neuropharmacology.

Effects of once‐weekly semaglutide on appetite, energy intake, control of eating, food preference and body weight in subjects with obesity

G. Finlayson, J. Blundell, A. Flint, 2017, Diabetes, obesity & metabolism.

Crystal Structure and Pharmacological Characterization of a Novel N-Methyl-d-aspartate (NMDA) Receptor Antagonist at the GluN1 Glycine Binding Site*

J. Greenwood, J. Kastrup, M. Gajhede, 2013, The Journal of Biological Chemistry.

Molecular Mechanism of a Novel GluN 1 Glycine-Site Antagonist ! " ! ! Crystal Structure and Pharmacological Characterization of a Novel NMDA Receptor Antagonist at the GluN 1 Glycine Binding Site

J. Greenwood, J. Kastrup, M. Gajhede, 2013 .

A new metabotropic glutamate receptor agonist with in vivo anti-allodynic activity.

Dennis K. Taylor, E. Tiekink, J. M. Mathiesen, 2010, Bioorganic & medicinal chemistry.

1,2,3‐Triazolyl Amino Acids as AMPA Receptor Ligands.

J. M. Mathiesen, A. Abell, T. Kvist, 2011 .

Pharmacology and Structural Analysis of Ligand Binding to the Orthosteric Site of Glutamate-Like GluD2 Receptors

P. Naur, L. Olsen, J. Kastrup, 2016, Molecular Pharmacology.

GluD2: GluD2 receptors containing the lurcher mutation iGluRs: Ionotropic glutamate receptors ITC: Isothermal titration calorimetry LBD: Ligand binding domain LTP: Long-term potentiation LTD: Long-term depression NMDA: N-methyl-D-aspartate NMDAR: NMDA receptor PSD: Postsynaptic density SAR: Structur

P. Naur, M. Gajhede, S. Traynelis, 2015 .

(1S, 3S)-3-amino-4-difluoromethylenyl-1-cyclopentanoic acid (CPP-115), a potent γ-aminobutyric acid aminotransferase inactivator for the treatment of cocaine addiction.

J. Brodie, A. Schousboe, C. Craft, 2012, Journal of medicinal chemistry.

Implementation of a Fluorescence-Based Screening Assay Identifies Histamine H3 Receptor Antagonists Clobenpropit and Iodophenpropit as Subunit-Selective N-Methyl-d-Aspartate Receptor Antagonists

J. Snyder, Yuhong Du, S. Traynelis, 2010, Journal of Pharmacology and Experimental Therapeutics.

Semaglutide Improves Postprandial Glucose and Lipid Metabolism and Delays First-Hour Gastric Emptying in Subjects with Obesity

J. Blundell, A. Flint, T. Kvist, 2016 .

The use of Xenopus oocytes in drug screening

K. Hansen, H. Bräuner‐Osborne, T. Kvist, 2011, Expert opinion on drug discovery.