C. Augelli-Szafran

发表

Rational design of 7-arylquinolines as non-competitive metabotropic glutamate receptor subtype 5 antagonists.

A. Mutlib, J. Milbank, C. Knauer, 2007, Bioorganic & medicinal chemistry letters.

Synthesis and SAR of 2-aryl pyrido[2,3-d]pyrimidines as potent mGlu5 receptor antagonists.

Susan Deeter, S. Bove, C. Knauer, 2007, Bioorganic & medicinal chemistry letters.

Chapter 3. Metabotropic glutamate receptors: Agonists, antagonists and allosteric modulators

C. Augelli-Szafran, R. Schwarz, 2003 .

Synthesis and SAR comparison of regioisomeric aryl naphthyridines as potent mGlu5 receptor antagonists.

S. Bove, J. Milbank, C. Knauer, 2007, Bioorganic & medicinal chemistry letters.

Novel Potent Human Ether-à-Go-Go-Related Gene (hERG) Potassium Channel Enhancers and Their in Vitro Antiarrhythmic Activity

Jun Zhou, Jason S. Cordes, W. Volberg, 2005, Molecular Pharmacology.

Discovery of Notch-Sparing γ-Secretase Inhibitors

M. Wolfe, Han-Xun Wei, Ting Yang, 2010 .

Quantification of gamma-secretase modulation differentiates inhibitor compound selectivity between two substrates Notch and amyloid precursor protein

W. Xia, Yongli Gu, C. Augelli-Szafran, 2008, Molecular Brain.

Part 1: Notch-sparing γ-secretase inhibitors: The identification of novel naphthyl and benzofuranyl amide analogs.

D. Selkoe, M. Wolfe, Han-Xun Wei, 2016, Bioorganic & medicinal chemistry letters.

Part 2. Notch-sparing γ-secretase inhibitors: The study of novel γ-amino naphthyl alcohols.

D. Selkoe, M. Wolfe, Han-Xun Wei, 2016, Bioorganic & medicinal chemistry letters.

A new synthetic route to 1,25-dihydroxy-vitamin D3

Stephen R. Wilson, C. Augelli-Szafran, A. Yasmin, 1991 .

Design, synthesis, and biological activity of novel polycyclic aza-amide FKBP12 ligands.

E. Lunney, S. Bender, R. Showalter, 2006, Journal of medicinal chemistry.

Synthesis and pharmacology of benzoxazines as highly selective antagonists at M4 muscarinic receptors

T. Pugsley, H. Hallak, C. Augelli-Szafran, 2002 .

Identification and characterization of m4 selective muscarinic antagonists.

J. Jaén, C. Augelli-Szafran, R. Schwarz, 1995, Bioorganic & medicinal chemistry letters.

Inhibitors of acyl-CoA:cholesterol acyltransferase. 5. Identification and structure-activity relationships of novel beta-ketoamides as hypocholesterolemic agents.

C. J. Blankley, R. Stanfield, B. Roth, 1993, Journal of medicinal chemistry.

A new reaction in organosilicon chemistry: the oxidative ring closure of allylsilanes with ceric ammonium nitrate

Stephen R. Wilson, C. Augelli-Szafran, C. Augelli-Szafran, 1988 .

The synthesis and structure-activity relationship of substituted N-phenyl anthranilic acid analogs as amyloid aggregation inhibitors.

Harry LeVine, H. Levine, L. Walker, 2009, Bioorganic & medicinal chemistry letters.

Phenotypic analysis of images of zebrafish treated with Alzheimer's γ-secretase inhibitors

Stephen T. C. Wong, Xiaoyin Xu, Weiming Xia, 2010, BMC biotechnology.

Cholecystokinin B antagonists. Synthesis and quantitative structure-activity relationships of a series of C-terminal analogues of CI-988.

B K Trivedi, D. Ortwine, B. Roth, 1996, Bioorganic & medicinal chemistry.

Discovery of Novel Delta Opioid Receptor (DOR) Inverse Agonist and Irreversible (Non-Competitive) Antagonists

J. Streicher, C. Augelli-Szafran, Parthasaradhireddy Tanguturi, 2021, Molecules.

Gamma-secretase as a target for Alzheimer's disease therapy: Small-molecule development

D. Selkoe, M. Wolfe, Han-Xun Wei, 2013, Alzheimer's & Dementia.

Clioquinol and other hydroxyquinoline derivatives inhibit Aβ(1–42) oligomer assembly

H. Levine, John A. Walker, Q. Ding, 2009, Neuroscience Letters.

Retraction of "Design and Synthesis of Novel Cyclic Amine Benzimidazoles for the Treatment of Pancreatic Cancer".

Yonghe Li, Wenyan Lu, Han-Xun Wei, 2017, Journal of medicinal chemistry.

Design and synthesis of m1-selective muscarinic agonists: (R)-(-)-(Z)-1-Azabicyclo[2.2.1]heptan-3-one, O-(3-(3'-methoxyphenyl)-2-propynyl)oxime maleate (CI-1017), a functionally m1-selective muscarinic agonist.

M. Brann, S. Barrett, H. Tecle, 1998, Journal of medicinal chemistry.

Discovery of notch-sparing gamma-secretase inhibitors.

M. Wolfe, P. Osenkowski, W. Ye, 2010, Current Alzheimer research.

Dihydroxybenzoic acid isomers differentially dissociate soluble biotinyl-Aβ(1-42) oligomers.

H. Levine, C. Augelli-Szafran, Lina Abdelmoti, 2012, Biochemistry.

Analogs of M4 selective synthetic muscarinic receptor antagonists: Synthesis, binding and pharmacokinetic properties

H. Hallak, C. Augelli-Szafran, R. Schwarz, 2002 .

Retraction of "Design and Synthesis of Novel Cyclic Amine Benzimidazoles for the Treatment of Pancreatic Cancer".

Yonghe Li, Wenyan Lu, Han-Xun Wei, 2017, Journal of medicinal chemistry.

The synthesis and structure-activity relationship of substituted N-phenyl anthranilic acid analogs as amyloid aggregation inhibitors.

H. Levine, L. Walker, M. Callahan, 2009, Bioorganic & medicinal chemistry letters.

Part 3: Notch-sparing γ-secretase inhibitors: SAR studies of 2-substituted aminopyridopyrimidinones.

D. Selkoe, M. Wolfe, Han-Xun Wei, 2016, Bioorganic & medicinal chemistry letters.