U. Sidelmann

发表

Small-molecule agonists for the glucagon-like peptide 1 receptor

Jeppe Sturis, Jarek Kostrowicki, Carsten Behrens, 2007, Proceedings of the National Academy of Sciences.

Synthesis, isolation and identification of glucuronides and mercapturic acids of a novel antiparasitic agent, licochalcone A.

S. Christensen, S. Hansen, U. Braumann, 1997, Xenobiotica; the fate of foreign compounds in biological systems.

Multivariate Analysis of High-Field NMR Data in Food and Medicine

M. Dyrby, S. Engelsen, L. Nørgaard, 2004 .

Directly coupled HPLC-NMR and HPLC-MS approaches for the rapid characterisation of drug metabolites in urine: application to the human metabolism of naproxen.

S. Hansen, J. Lindon, J. Nicholson, 2001, Journal of pharmaceutical and biomedical analysis.

Development of a simple liquid chromatographic method for the separation of mixtures of positional isomers and anomers of synthetic 2-, 3- and 4-fluorobenzoic acid glucuronides formed via acyl migration reactions.

I. Wilson, S. Hansen, J. Lindon, 1996, Journal of chromatography. B, Biomedical applications.

High-performance liquid chromatography directly coupled to 19F and 1H NMR for the analysis of mixtures of isomeric ester glucuronide conjugates of trifluoromethylbenzoic acids

John W. Gilbert, I. Wilson, J. Lindon, 1996 .

Identification of the Positional Isomers of 2-Fluorobenzoic acid 1-O-Acyl Glucuronide by Directly Coupled HPLC-NMR

I. Wilson, J. Lindon, J. Nicholson, 1995 .

New β-Alanine Derivatives Are Orally Available Glucagon Receptor Antagonists

C. Behrens, L. B. Knudsen, C. L. Brand, 2007 .

Purification and 1H NMR spectroscopic characterization of phase II metabolites of tolfenamic acid.

S. Hansen, C. Cornett, J. Tjørnelund, 1997, Drug metabolism and disposition: the biological fate of chemicals.

Optimization of alkylidene hydrazide based human glucagon receptor antagonists. Discovery of the highly potent and orally available 3-cyano-4-hydroxybenzoic acid [1-(2,3,5,6-tetramethylbenzyl)-1H-indol-4-ylmethylene]hydrazide.

A. Kuki, Michael D. Johnson, D. Murphy, 2002, Journal of medicinal chemistry.

New beta-alanine derivatives are orally available glucagon receptor antagonists.

C. Behrens, L. B. Knudsen, C. L. Brand, 2007, Journal of medicinal chemistry.

Human glucagon receptor antagonists based on alkylidene hydrazides.

A. Kuki, D. Murphy, A. Polinsky, 2002, Bioorganic & medicinal chemistry letters.

LC-1H NMR used for determination of the elution order of S-naproxen glucuronide isomers in two isocratic reversed-phase LC-systems.

S. Hansen, J. Lindon, J. Nicholson, 2001, Journal of pharmaceutical and biomedical analysis.

Isolation and Characterization of Major Phase I and II Metabolites of Ibuprofen

S. Hansen, U. Sidelmann, D. R. Kepp, 1997, Pharmaceutical Research.

Simultaneous quantitative determination of the major phase I and II metabolites of ibuprofen in biological fluids by high-performance liquid chromatography on dynamically modified silica.

S. Hansen, J. Tjørnelund, U. Sidelmann, 1997, Journal of chromatography. B, Biomedical sciences and applications.

S-naproxen-beta-1-O-acyl glucuronide degradation kinetic studies by stopped-flow high-performance liquid chromatography-1H NMR and high-performance liquid chromatography-UV.

S. Hansen, J. Lindon, J. Nicholson, 2001, Drug metabolism and disposition: the biological fate of chemicals.

Contemporary issues in toxicology the role of metabonomics in toxicology and its evaluation by the COMET project.

Henrik Antti, Elaine Holmes, John C Lindon, 2003, Toxicology and applied pharmacology.

Quantification of lipoprotein subfractions using 1H-NMR and chemometrics

M. Dyrby, S. Engelsen, L. Nørgaard, 2003 .

Stereospecific pH-dependent degradation kinetics of R- and S-naproxen-beta-l-O-acyl-glucuronide.

S. Hansen, J. Tjørnelund, U. Sidelmann, 2002, Chirality.

Glucagon receptor antagonism improves islet function in mice with insulin resistance induced by a high-fat diet

F. Sundler, N. Wierup, B. Ahrén, 2007, Diabetologia.

Novel glucagon receptor antagonists with improved selectivity over the glucose-dependent insulinotropic polypeptide receptor.

C. Behrens, L. B. Knudsen, E. Nishimura, 2008, Journal of medicinal chemistry.

Direct quantitative trait locus mapping of mammalian metabolic phenotypes in diabetic and normoglycemic rat models

Dominique Gauguier, Jeremy K Nicholson, M. Bihoreau, 2007, Nature Genetics.

Measurement of Internal Acyl Migration Reaction Kinetics Using Directly Coupled HPLC-NMR: Application for the Positional Isomers of Synthetic (2-Fluorobenzoyl)-d-glucopyranuronic Acid.

I. Wilson, S. Hansen, J. Lindon, 1996, Analytical chemistry.

750 MHz HPLC-NMR spectroscopic studies on the separation and characterization of the positional isomers of the glucuronides of 6,11-dihydro-11-oxodibenz[b,e]oxepin-2-acetic acid.

I. Wilson, M. Hofmann, M. Spraul, 1996, Analytical chemistry.

Combination of ‘omics’ data to investigate the mechanism(s) of hydrazine-induced hepatotoxicity in Rats and to identify potential biomarkers

D. Baunsgaard, U. Sidelmann, T G Klenø, 2004, Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals.

CYP2C8 and CYP3A4 are the principal enzymes involved in the human in vitro biotransformation of the insulin secretagogue repaglinide.

I. Bjørnsdottir, M. Thomsen, Tanja Busk Bidstrup, 2003, British journal of clinical pharmacology.

Directly Coupled 800 MHz HPLC−NMR Spectroscopy of Urine and Its Application to the Identification of the Major Phase II Metabolites of Tolfenamic Acid

Martin Hofmann, John C. Lindon, Manfred Spraul, 1997 .

Directly coupled HPLC-NMR and its application to drug metabolism.

I. Wilson, J. Lindon, J. Nicholson, 1997, Drug metabolism reviews.

A comparative study of precision cut liver slices, hepatocytes, and liver microsomes from the Wistar rat using metronidazole as a model substance.

S. Hansen, C. Cornett, J. Tjørnelund, 1996, Xenobiotica; the fate of foreign compounds in biological systems.