A. Kłodzińska

发表

Potential anxiolytic‐ and antidepressant‐like effects of MPEP, a potent, selective and systemically active mGlu5 receptor antagonist

F. Gasparini, R. Kuhn, Andrzej Pilc, 2001, British journal of pharmacology.

Synthesis, 5-HT1A and 5-HT2A receptor activity of new 1-phenylpiperazinylpropyl derivatives with arylalkyl substituents in position 7 of purine-2,6-dione.

M. Pawłowski, A. Kłodzińska, B. Duszyńska, 2001, Polish journal of pharmacology.

1-Aryl-4-(4-succinimidobutyl)piperazines and their conformationally constrained analogues: synthesis, binding to serotonin (5-HT1A, 5-HT2A, 5-HT7), alpha1-adrenergic, and dopaminergic D2 receptors, and in vivo 5-HT1A functional characteristics.

A. Bojarski, E. Tatarczyńska, A. Kłodzińska, 2005, Bioorganic & medicinal chemistry.

5-HT1A-receptor agonists restore behavior of rats when disturbed by L-dihydroxyphenylalanine

A. Kłodzińska, N. Bondarenko, L. Baran, 1990, Bulletin of Experimental Biology and Medicine.

Pharmacological properties and SAR of new 1,4‐disubstituted piperazine derivatives with hypnotic‐sedative activity

Z. Chilmonczyk, J. Nowak, A. Kłodzińska, 2002, The Journal of pharmacy and pharmacology.

Structure-intrinsic activity relationship studies in the group of 1-imido/amido substituted 4-(4-arylpiperazin-1-yl)cyclohexane derivatives; new, potent 5-HT1A receptor agents with anxiolytic- like activity.

A. Bojarski, E. Tatarczyńska, A. Kłodzińska, 2006, Bioorganic & medicinal chemistry.

Synthesis, in vitro and in vivo 5-HT1A/5-HT2A serotonin receptor activity of new hybrid 1,2,3,4-tetrahydro-gamma-carbolines with 1-(2-methoxyphenyl)piperazine moiety.

A. Bojarski, E. Tatarczyńska, A. Kłodzińska, 2003, Polish journal of pharmacology.

Synthesis and 5-HT1A/5-HT2A receptor activity of new N-[3-(4-phenylpiperazin-1-yl)-propyl] derivatives of 3-spiro-cyclohexanepyrrolidine-2,5-dione and 3-spiro-beta-tetralonepyrrolidine-2,5-dione.

M. Kołaczkowski, M. Pawłowski, E. Tatarczyńska, 2003, Polish journal of pharmacology.

Synthesis and pharmacological evaluation of new arylpiperazines. 3-[4-[4-(3-chlorophenyl)-1-piperazinyl]butyl]-quinazolidin-4-one - a dual serotonin 5-HT(1A)/5-HT(2A) receptor ligand with an anxiolytic-like activity.

A. Bojarski, T. Kowalska, P. Kowalski, 2002, Bioorganic & medicinal chemistry.

Involvement of 5-HT1B receptors in the anticonflict effect of m-CPP in rats

A. Kłodzińska, E. Chojnacka-wójcik, 2005, Journal of Neural Transmission / General Section JNT.

In the Amygdala Anxiolytic Action of mGlu5 Receptors Antagonist MPEP Involves Neuropeptide Y but not GABAA Signaling

F. Gasparini, M. Śmiałowska, B. Szewczyk, 2004, Neuropsychopharmacology.

Multiple MPEP administrations evoke anxiolytic- and antidepressant-like effects in rats

G. Nowak, J. Wierońska, Andrzej Pilc, 2002, Neuropharmacology.

Potential anti-anxiety, anti-addictive effects of LY 354740, a selective group II glutamate metabotropic receptors agonist in animal models

Andrzej Pilc, A. Kłodzińska, A. Pałucha, 1999, Neuropharmacology.

Biologically active preparations from Lactuca virosa L.

A. Kłodzińska, W. Kisiel, E. Chojnacka-wójcik, 1992 .

Anxiolytic-like effects of PHCCC, an allosteric modulator of mGlu4 receptors, in rats.

Andrzej Pilc, A. Kłodzińska, K. Stachowicz, 2004, European journal of pharmacology.

4-(3-furyl)-2-(4-methylpiperazino)pyrimidines: Potent 5-HT2A receptor antagonists

L. Strekowski,, T. Baranowski, A. Kłodzińska, 1997 .

1,2,3,4-tetrahydroisoquinoline derivatives: a new class of 5-HT1A receptor ligands.

A. Bojarski, E. Tatarczyńska, A. Kłodzińska, 1999, Bioorganic & medicinal chemistry.

The influence of substitution at aromatic part of 1,2,3,4-tetrahydroisoquinoline on in vitro and in vivo 5-HT(1A)/5-HT(2A) receptor activities of its 1-adamantoyloaminoalkyl derivatives.

A. Bojarski, A. Kozioł, A. Wesołowska, 2002, Bioorganic & medicinal chemistry.

The group III mGlu receptor agonist ACPT-I exerts anxiolytic-like but not antidepressant-like effects, mediated by the serotonergic and GABA-ergic systems

S. Schann, Andrzej Pilc, A. Kłodzińska, 2009, Neuropharmacology.

Peripheral administration of group III mGlu receptor agonist ACPT-I exerts potential antipsychotic effects in rodents

Andrzej Pilc, A. Kłodzińska, K. Stachowicz, 2008, Neuropharmacology.

The anxiolytic-like activity of AIDA (1-aminoindan-1,5-dicarboxylic acid), an mGLu 1 receptor antagonist.

E. Tatarczyńska, A. Kłodzińska, K. Stachowicz, 2004, Journal of physiology and pharmacology : an official journal of the Polish Physiological Society.

Anxiolytic-like effects of preferential dopamine D3 receptor agonists in an animal model.

G. Skuza, A. Kłodzińska, Z. Rogóż, 2003, Polish journal of pharmacology.

5-HT1A and 5-HT2A receptor affinity and functional profile of some N-[3-(4-aryl-1-piperazinyl)propyl] derivatives of indolin-2(1H)-one, quinolin-2(1 H)-one and isoquinolin-1(2H)-one. Part 30: Structure-activity relationship studies of CNS agents.

T. Kowalska, P. Kowalski, E. Tatarczyńska, 1997, Pharmazie.

Central action of ipsapirone, a new anxiolytic drug, on serotoninergic, noradrenergic and dopaminergic functions

E. Tatarczyńska, A. Kłodzińska, J. Maj, 2005, Journal of Neural Transmission.

Synthesis, pharmacological properties and SAR of new 1,4-disubstituted piperazine derivatives with hypnotic-sedative activity

Z. Chilmonczyk, E. Tatarczyńska, A. Kłodzińska, 2004 .

Effect of combined administration of 5-HT1A or 5-HT1B/1D receptor antagonists and antidepressants in the forced swimming test.

E. Tatarczyńska, A. Kłodzińska, K. Stachowicz, 2004, European journal of pharmacology.

Effects of combined administration of 5-HT1A and/or 5-HT1B receptor antagonists and paroxetine or fluoxetine in the forced swimming test in rats.

E. Tatarczyńska, A. Kłodzińska, E. Chojnacka-wójcik, 2002, Polish journal of pharmacology.

The antianxiety-like effects of antagonists of group I and agonists of group II and III metabotropic glutamate receptors after intrahippocampal administration

Andrzej Pilc, E. Tatarczyńska, A. Kłodzińska, 2001, Psychopharmacology.

Synthesis and 5-HT1A, 5-HT2A receptor activity of new β-tetralonohydantoins

M. Pawłowski, A. Bojarski, G. Nowak, 2005 .

Structure‐Activity Relationship Studies of CNS Agents, Part 26 4‐[2‐(Cycloalkanecarboxamido)ethyl]‐1‐(2‐methoxyphenyl)‐piperazines: High‐Affinity 5‐HT1A Agonists

A. Kłodzińska, J. Mokrosz, S. Charakchieva‐Minol, 1995 .

A new putative 5-HT1A receptor antagonist of the 1-arylpiperazine class of ligands

A. Drabczyńska, M. Pawłowski, A. Kłodzińska, 1995 .

Structure‐Activity Relationship Studies of CNS Agents, XXI: Two Derivatives of 1‐(o‐Methoxyphenyl)piperazine with an Opposite Function at 5‐HT1A Receptors

A. Bojarski, A. Kłodzińska, J. Mokrosz, 1995, Archiv der Pharmazie.

Hyperthermia induced bym-trifluoromethylphenylpiperazine (TFMPP) orm-chlorophenylpiperazine (m-CPP) in heat-adapted rats

A. Kłodzińska, E. Chojnacka-wójcik, 2005, Psychopharmacology.

Group II mGlu receptor agonists inhibit behavioural and electrophysiological effects of DOI in mice

Andrzej Pilc, A. Kłodzińska, K. Tokarski, 2002, Pharmacology Biochemistry and Behavior.

The anxiolytic‐like effect of 5‐HT1B receptor ligands in rats: a possible mechanism of action

E. Tatarczyńska, A. Kłodzińska, E. Chojnacka-wójcik, 2005, The Journal of pharmacy and pharmacology.

Effects of a selective 5-HT1B receptor agonist and antagonists in animal models of anxiety and depression

E. Tatarczyńska, A. Kłodzińska, K. Stachowicz, 2004, Behavioural pharmacology.

Anxiolytic-like effects of MTEP, a potent and selective mGlu5 receptor agonist does not involve GABAA signaling

G. Nowak, Andrzej Pilc, E. Tatarczyńska, 2004, Neuropharmacology.

Anticonflict effect of the glycineB receptor partial agonist, D-cycloserine, in rats. Pharmacological analysis

A. Kłodzińska, E. Chojnacka-wójcik, 2000, Psychopharmacology.

Structure-Activity Relationship Studies of CNS Agents. Part 18. 1-((2- Methoxyphenyl)-4-(4-succinimido)butyl)piperazine (MM-77): A New, Potent, Postsynaptic Antagonist of 5-HT1A Receptors.

M. Filip, E. Tatarczyńska, A. Kłodzińska, 1995 .

The role of postsynaptic 5-HT1A receptors in the anticonflict effect of ipsapirone

E. Przegaliński, E. Tatarczyńska, A. Kłodzińska, 1994, Neuropharmacology.

Hypothermia induced by m-trifluoromethylphenylpiperazine or m-chlorophenylpiperazine: an effect mediated by 5-HT1B receptors?

A. Kłodzińska, J. Maj, E. Chojnacka-wójcik, 2005, Journal of Neural Transmission.

4,6-Di(heteroaryl)-2-(N-methylpiperazino)pyrimidines as New, Potent 5-HT2A Receptor Ligands: A Verification of the Topographic Model

L. Strekowski,, A. Bojarski, S. Dove, 1996 .

Influence of the terminal amide fragment geometry in some 3-arylideneindolin-2(1H)-ones on their 5-HT1A/5-HT2A receptor activity.

A. Kozioł, A. Kłodzińska, M. Mokrosz, 2001, Bioorganic & medicinal chemistry letters.

Roles of group II metabotropic glutamate receptors in modulation of seizure activity

S. Czuczwar, Andrzej Pilc, A. Kłodzińska, 2000, Naunyn-Schmiedeberg's Archives of Pharmacology.

Antidepressant-like effect of the selective 5-HT1B receptor agonist CP 94253: a possible mechanism of action.

E. Tatarczyńska, A. Kłodzińska, K. Stachowicz, 2005, European journal of pharmacology.

A role for glutamate in the treatment of anxiety and depression: Focus on group I metabotropic glutamate (mGlu) receptors

G. Nowak, Andrzej Pilc, A. Kłodzińska, 2002 .

Interaction of 1,2,4-substituted piperazines, new serotonin receptor ligands, with 5-HT1A and 5-HT2A receptors.

I. Sylte, A. Bronowska, A. Leś, 2002, Farmaco.

2-H- and 2-acyl-9- [omega-[4-(2-methoxyphenyl)piperazinyl]-alkyl]-1,2,3,4-tetrahydro-beta-carbolines as ligands of 5-HT1A and 5-HT2A receptors.

A. Wesołowska, E. Tatarczyńska, A. Kłodzińska, 2001, Polish journal of pharmacology.

Involvement of 5-hydroxytryptamine 2A (5-HT2A) receptors in the mediation of the discriminative stimulus properties of (+/-)DOI in rats.

A. Kłodzińska, E. Chojnacka-wójcik, 1997, Polish Journal of Pharmacology.

New 4-[omega-(diarylmethylamino)alkyl]- and 4-[omega-(diarylmethoxy)alkyl]-1-arylpiperazines as selective 5-HT1A/5-HT2A receptor ligands with differentiated in vivo activity.

E. Tatarczyńska, A. Kłodzińska, K. Stachowicz, 2004, Polish journal of pharmacology.

Glutamate receptor ligands as anxiolytics.

Andrzej Pilc, A. Kłodzińska, E. Chojnacka-wójcik, 2001, Current opinion in investigational drugs.

Anxiolytic-like effects of group I metabotropic glutamate antagonist 2-methyl-6-(phenylethynyl)-pyridine (MPEP) in rats.

Andrzej Pilc, E. Tatarczyńska, A. Kłodzińska, 2000, Polish journal of pharmacology.

Anxiolytic-like effects of MTEP, a potent and selective mGlu5 receptor agonist does not involve GABA(A) signaling.

N. Cosford, G. Nowak, Andrzej Pilc, 2004, Neuropharmacology.

Structure‐Activity Relationship Studies of CNS Agents, Part 25: 4,6‐Di(heteroaryl)‐2‐(N‐methylpiperazino)pyrimidines as New, Potent 5‐HT2A Receptor Ligands: A Verification of the Topographic Model

L. Strekowski,, A. Bojarski, S. Dove, 1996, Archiv der Pharmazie.

Novel 1,4‐Benzoxazin‐3(4H)‐one, 1,2‐Benzoxazolin‐3‐one and 1,3‐Benzoxazolin‐2,4‐dione Arylpiperazine Derivatives with Different 5‐HT1A and Antagonistic 5‐HT2A Activities

A. Bojarski, T. Kowalska, P. Kowalski, 1999, Archiv der Pharmazie.

Effects of GABAB receptor ligands in rodent tests of anxiety-like behavior.

G. Nowak, T. Librowski, A. Partyka, 2007, Pharmacological reports : PR.

1,2,3,4-tetrahydroisoquinoline derivatives: a new class of 5-HT1A receptor ligands.

A. Bojarski, E. Tatarczyńska, A. Kłodzińska, 1999, Bioorganic & medicinal chemistry.

Anxiolytic-like effect of nafadotride and PNU 99194A, dopamine D3 receptor antagonists in animal models.

A. Kłodzińska, Z. Rogóż, J. Maj, 2000, Polish journal of pharmacology.