J. Salovich

发表

Discovery and characterization of a novel series of N-phenylsulfonyl-1H-pyrrole picolinamides as positive allosteric modulators of the metabotropic glutamate receptor 4 (mGlu4).

Anna L. Blobaum, C. Lindsley, C. Hopkins, 2016, Bioorganic & medicinal chemistry letters.

Discovery and optimization of imidazo[1,2-a]pyridine inhibitors of insulin-like growth factor-1 receptor (IGF-1R).

Brian J. Wilson, L. Shewchuk, P. Sabbatini, 2009, Bioorganic & medicinal chemistry letters.

Synthesis of 2,3-diarylsubstituted indazoles utilizing a Suzuki cross-coupling/deprotection/N-arylation sequence.

C. Lindsley, C. Hopkins, J. Salovich, 2010, Tetrahedron letters.

Imidazo[5,1-f][1,2,4]triazin-2-amines as novel inhibitors of polo-like kinase 1.

L. Shewchuk, T. J. Lansing, R. Mook, 2008, Bioorganic & medicinal chemistry letters.

Regioselective synthesis of benzimidazole thiophene inhibitors of polo-like kinase 1

M. Cheung, J. Salovich, K. Hornberger, 2008 .

Discovery of Potent 2-Aryl-6,7-dihydro-5 H-pyrrolo[1,2- a]imidazoles as WDR5-WIN-Site Inhibitors Using Fragment-Based Methods and Structure-Based Design.

E. Olejniczak, S. Fesik, O. Rossanese, 2018, Journal of medicinal chemistry.

Stereoselective synthesis of a nonracemic hydronaphthalene subunit of kijanolide

B. Shearer, J. A. Marshall, J. Salovich, 1990 .

Discovery, Synthesis, and Preclinical Characterization of N-(3-Chloro-4-fluorophenyl)-1H-pyrazolo[4,3-b]pyridin-3-amine (VU0418506), a Novel Positive Allosteric Modulator of the Metabotropic Glutamate Receptor 4 (mGlu4).

Anna L. Blobaum, J. Macor, C. Lindsley, 2016, ACS chemical neuroscience.

Discovery of thiophene inhibitors of polo-like kinase.

D. Drewry, T. J. Lansing, R. Mook, 2009, Bioorganic & medicinal chemistry letters.

Discovery and Structure-Based Optimization of Benzimidazole-Derived Activators of SOS1-Mediated Nucleotide Exchange on RAS.

S. Fesik, A. Waterson, O. Rossanese, 2018, Journal of medicinal chemistry.

Identification of ML204, a Novel Potent Antagonist That Selectively Modulates Native TRPC4/C5 Ion Channels*

Melissa R. Miller, O. McManus, C. Lindsley, 2011, The Journal of Biological Chemistry.

Efficacy of GSK461364, a selective Plk1 inhibitor, in human tumor xenograft models

J. Jackson, A. Gilmartin, Pearl S Huang, 2007 .

Discovery of N-(4-methoxy-7-methylbenzo[d]thiazol-2-yl)isonicatinamide, ML293, as a novel, selective and brain penetrant positive allosteric modulator of the muscarinic 4 (M4) receptor.

Anna L. Blobaum, D. Sheffler, C. Lindsley, 2012, Bioorganic & medicinal chemistry letters.

Regioselective Synthesis of Benzimidazole Thiophene Inhibitors of Polo‐Like Kinase 1.

M. Cheung, J. Salovich, K. Hornberger, 2009 .

Identification of ML 204 , a Novel Potent Antagonist That Selectively Modulates Native TRPC 4 / C 5 Ion Channels *

Melissa R. Miller, O. McManus, C. Lindsley, 2011 .

Novel M4 positive allosteric modulators derived from questioning the role and impact of a presumed intramolecular hydrogen-bonding motif in β-amino carboxamide-harboring ligands.

C. Lindsley, P. Conn, C. Niswender, 2019, Bioorganic & medicinal chemistry letters.

Synthesis and SAR of a novel metabotropic glutamate receptor 4 (mGlu4) antagonist: unexpected 'molecular switch' from a closely related mGlu4 positive allosteric modulator.

C. Lindsley, C. Hopkins, C. Niswender, 2011, Bioorganic & medicinal chemistry letters.

The discovery of VU0486846: steep SAR from a series of M1 PAMs based on a novel benzomorpholine core.

Anna L. Blobaum, C. Lindsley, Hyekyung P. Cho, 2018, Bioorganic & medicinal chemistry letters.

Novel Chemical Inhibitor of TRPC4 Channels

Julie L. Engers, Melissa R. Miller, O. McManus, 2011 .