C. Salhoff

发表

Synthesis of the four isomers of 4-aminopyrrolidine-2,4-dicarboxylate: identification of a potent, highly selective, and systemically-active agonist for metabotropic glutamate receptors negatively coupled to adenylate cyclase.

D. Schoepp, D. Lodge, T. Howe, 1996, Journal of medicinal chemistry.

Design, synthesis, and pharmacological characterization of (+)-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylic acid (LY354740): a potent, selective, and orally active group 2 metabotropic glutamate receptor agonist possessing anticonvulsant and anxiolytic properties.

D. Schoepp, T. Howe, S. M. Massey, 1997, Journal of medicinal chemistry.

LY354740 is a Potent and Highly Selective Group II Metabotropic Glutamate Receptor Agonist in Cells Expressing Human Glutamate Receptors

D. Schoepp, D. Bleakman, J. Monn, 1997, Neuropharmacology.

Pharmacological Characterization of the Competitive GLUK5 Receptor Antagonist Decahydroisoquinoline LY466195 in Vitro and in Vivo

David Bleakman, Kirk W. Johnson, Andrew Alt, 2006, Journal of Pharmacology and Experimental Therapeutics.

Selective inhibition of forskolin-stimulated cyclic AMP formation in rat hippocampus by a novel mGluR agonist, 2R,4R-4-aminopyrrolidine-2,4-dicarboxylate

D. Schoepp, D. D. Schoepp, B. G. Johnson, 1995, Neuropharmacology.

Synthesis of the Four Isomers of 4‐Aminopyrrolidine‐2,4‐dicarboxylate: Identification of a Potent, Highly Selective, and Systemically‐Active Agonist for Metabotropic Glutamate Receptors Negatively Coupled to Adenylate Cyclase.

D. Schoepp, D. Lodge, T. Howe, 1996 .

The Novel Metabotropic Glutamate Receptor Agonist 2R,4R-APDC Potentiates Stimulation of Phosphoinositide Hydrolysis in the Rat Hippocampus by 3,5-dihydroxyphenylglycine: Evidence for a Synergistic Interaction Between Group 1 and Group 2 Receptors

D. Schoepp, J. Monn, B. Johnson, 1996, Neuropharmacology.

Genetic deletion of CB1 receptors improves non-associative learning

G. Nomikos, C. Salhoff, R. Davis, 2005, Behavioural Brain Research.

The Potent, Selective mGlu2/3 Receptor Agonist LY379268 Increases Extracellular Levels of Dopamine, 3,4‐Dihydroxyphenylacetic Acid, Homovanillic Acid, and 5‐Hydroxyindole‐3‐Acetic Acid in the Medial Prefrontal Cortex of the Freely Moving Rat

K. Perry, D. Schoepp, J. Monn, 2000, Journal of neurochemistry.

DL-tetrazol-5-ylglycine, a highly potent NMDA agonist: its synthesis and NMDA receptor efficacy.

D. Schoepp, P. J. O'malley, L. J. Heinz, 1992, Journal of medicinal chemistry.

3,5‐Dihydroxyphenylglycine Is a Highly Selective Agonist for Phosphoinositide‐Linked Metabotropic Glutamate Receptors in the Rat Hippocampus

D. Schoepp, D D Schoepp, B G Johnson, 1994, Journal of neurochemistry.

In Vitro and In Vivo Pharmacology of trans‐ and cis‐(±)‐1‐Amino‐1,3‐Cyclopentanedicarboxylic Acid: Dissociation of Metabotropic and Ionotropic Excitatory Amino Acid Receptor Effects

M. Johnston, J. Mcdonald, D. Schoepp, 1991, Journal of neurochemistry.

In vivo pharmacological characterization of the structurally novel, potent, selective mGlu2/3 receptor agonist LY404039 in animal models of psychiatric disorders

K. Perry, D. McKinzie, J. Witkin, 2007, Psychopharmacology.

Dopamine and 5-HT turnover are increased by the mGlu2/3 receptor agonist LY379268 in rat medial prefrontal cortex, nucleus accumbens and striatum

K. Perry, D. Schoepp, J. Monn, 2000, Brain Research.

Mesolimbic Dopamine Super-Sensitivity in Melanin-Concentrating Hormone-1 Receptor-Deficient Mice

E. Tzavara, G. Nomikos, D. Gehlert, 2005, The Journal of Neuroscience.

Selective protection against AMPA- and kainate-evoked neurotoxicity by (3S,4aR,6R,8aR)-6-[2-(1(2)H-tetrazole-5-yl)ethyl]decahydroisoquinoline-3-carboxylic acid (LY293558) and its racemate (LY215490)

P. Ornstein, P. May, D. Schoepp, 2005, Journal of Neural Transmission.

In vitro and in vivo antagonism of AMPA receptor activation by (3s,4ar,6r,8ar)-6-[2-(1(2)h-tetrazole-5-yl)ethyl]decahydroisoquinoline-3-carboxylic acid

P. Ornstein, D. Schoepp, D. Bleakman, 1995, Neuropharmacology.

Potent, stereoselective, and brain region selective modulation of second messengers in the rat brain by (+)LY354740, a novel group II metabotropic glutamate receptor agonist

D. Schoepp, J. Monn, Bryan G. Johnson, 1998, Naunyn-Schmiedeberg's Archives of Pharmacology.

Design, Synthesis, and Pharmacological Characterization of (+)-2- Aminobicyclo(3.1.0)hexane-2,6-dicarboxylic Acid (LY354740): A Potent, Selective, and Orally Active Group 2 Metabotropic Glutamate Receptor Agonist Possessing Anticonvulsant and Anxiolytic Properties.

D. Schoepp, T. Howe, S. M. Massey, 1997 .

The CB1 receptor antagonist SR141716A selectively increases monoaminergic neurotransmission in the medial prefrontal cortex: implications for therapeutic actions

K. Perry, F. Bymaster, E. Tzavara, 2003, British journal of pharmacology.

Kochia scoparia Growth Response to Triazine Herbicides

Alex R. Martin, C. Salhoff, 1986, Weed Science.

Neuroprotectant effects of LY 274614, a structurally novel systemically active competitive NMDA receptor antagonist

P. Ornstein, D. Schoepp, C. Salhoff, 2005, Journal of Neural Transmission / General Section JNT.

CGS-19755 and MK-801 selectively prevent rat striatal cholinergic and gabaergic neuronal degeneration induced by N-methyl-D-aspartate and ibotenate in vivo

P. Ornstein, D. Schoepp, C. Salhoff, 2005, Journal of Neural Transmission / General Section JNT.

CNS distribution of metabotropic glutamate 2 and 3 receptors: Transgenic mice and [3H]LY459477 autoradiography

G. Marek, D. Schoepp, D. Calligaro, 2013, Neuropharmacology.

Exposure to an elevated platform increases plasma corticosterone and hippocampal acetylcholine in the rat: reversal by chlordiazepoxide.

E. Tzavara, G. Nomikos, C. Salhoff, 2004, European journal of pharmacology.

Second-messenger responses in brain slices to elucidate novel glutamate receptors

D. Schoepp, Bryan G. Johnson, R. Wright, 1995, Journal of Neuroscience Methods.

Excitatory amino acid-induced convulsions in neonatal rats mediated by distinct receptor subtypes.

P. Ornstein, D. Schoepp, B. Johnson, 1990, European journal of pharmacology.

Acute increases in monoamine release in the rat prefrontal cortex by the mGlu2/3 agonist LY379268 are similar in profile to risperidone, not locally mediated, and can be elicited in the presence of uptake blockade

K. Perry, D. Schoepp, J. Monn, 2001, Neuropharmacology.

Enzymatic resolution and pharmacological activity of the enantiomers of 3,5-dihydroxyphenylglycine, a metabotropic glutamate receptor agonist

D. Schoepp, C. Salhoff, R. C. Harden, 1995 .

Enzymatic Resolution and Pharmacological Activity of the Enantiomers of 3,5-Dihydroxyphenylglycine, a Metabotropic Glutamate Receptor Agonist.

D. Schoepp, C. Salhoff, R. C. Harden, 1995 .

The NMDA receptor agonist DL-(tetrazol-5-yl)glycine is a highly potent excitotoxin.

J. Mcdonald, D. Schoepp, C. Salhoff, 1994, European journal of pharmacology.

Pharmacological characterization of LY233053: a structurally novel tetrazole-substituted competitive N-methyl-D-aspartic acid antagonist with a short duration of action.

P. Ornstein, D. Schoepp, D. Lodge, 1990, The Journal of pharmacology and experimental therapeutics.