J. Leander

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Disinhibitory effects of LY354740, a new mGluR2 agonist, on behaviors suppressed by electric shock in rats and pigeons

J. Monn, C. Overshiner, M. Benvenga, 1999 .

Heteroatom-substitution as a strategy for increasing the potency of competitive NMDA antagonists.

P. Ornstein, D. Schoepp, D. Lodge, 1998, Bioorganic & medicinal chemistry letters.

Synthesis and pharmacological characterization of l-trans-4-tetrazolylproline (ly300020): A novel systemically-active ampa receptor agonist

D. Schoepp, D. Lodge, J. Monn, 1993 .

D,L-(tetrazol-5-yl) glycine: a novel and highly potent NMDA receptor agonist.

D. Schoepp, D. Lodge, A. Sacaan, 1991, European journal of pharmacology.

Effects of the appetite stimulant chlordimeform on food and water consumption of rats: comparison with chlordiazepoxide.

J. Witkin, J. Leander, 1982, The Journal of pharmacology and experimental therapeutics.

Effects of punishment‐attenuating drugs on deprivation‐induced drinking: Implications for conflict procedures

J. Leander, 1983 .

NMDA receptor antagonists inhibit catalepsy induced by either dopamine D1 or D2 receptor antagonists.

N. Moore, J. Leander, A. Blackman, 1993, European journal of pharmacology.

The behavioral pharmacology of NMDA receptor antagonists.

J. Leander, R. Balster, J. Willetts, 1990, Trends in pharmacological sciences.

Buprenorphine is a potent kappa-opioid receptor antagonist in pigeons and mice.

J. Leander, 1988, European journal of pharmacology.

Comparison of the effects of antipsychotics on a delayed radial maze task in the rat

J. Leander, M. Wolff, 2003, Psychopharmacology.

The novel 5-Hydroxytryptamine(1A) antagonist LY426965: effects on nicotine withdrawal and interactions with fluoxetine.

D. Wong, T. Branchek, J. Zgombick, 2000, The Journal of pharmacology and experimental therapeutics.

Absolute configurations and pharmacological activities of the optical isomers of fluoxetine, a selective serotonin-uptake inhibitor.

R. Fuller, J. Krushinski, D. Robertson, 1988, Journal of medicinal chemistry.

Increased food consumption by clozapine, but not by olanzapine, in satiated rats

M. Benvenga, J. Leander, 1997 .

Phencyclidine receptors in rat brain cortex.

D. Zimmerman, J. Leander, L. Mendelsohn, 1984, Biochemical pharmacology.

Rate-dependent Effects of drugs. II. effects of some major tranquilizers on multiple fixed-ratio, fixed-interval schedule performance.

J. Leander, 1975, The Journal of pharmacology and experimental therapeutics.

Anticonvulsant effects of phencyclidine-like drugs: relation to N-methyl-d-aspartic acid antagonism

D. Zimmerman, J. Leander, R. C. Rathbun, 1988, Brain Research.

Anticonvulsant Properties of N‐Substituted α,α‐Diamino Acid Derivatives

H. Kohn, D. Robertson, J. Leander, 1994 .

Pharmacology of LY201409, a Potent Benzamide Anticonvulsant

D. Robertson, J. Leander, R. C. Rathbun, 1988, Epilepsia.

Marked stereospecificity in a new class of anticonvulsants

H. Kohn, J. Leander, J. D. Conley, 1988, Brain Research.

Anticonvulsant effects of a novel aminobenzamide (LY201116) in mice

D. Robertson, J. Leander, R. Lawson, 1988, Neuropharmacology.

Pharmacological Effects of Enantiomers of 4‐Amino‐N‐(α‐methylbenzyl)Benzamide, a Chemically Novel Anticonvulsant

D. Robertson, C. R. Clark, J. Leander, 1988, Epilepsia.

A comparison of the behavioural effects of 5-HT and 2 A 5-HT receptor agonists in the pigeon 2

J. Leander, M. Wolff, 2002 .

Relation of Plasma and Brain Concentrations of the Anticonvulsant Ameltolide to Its Pharmacologic Effects

D. Lodge, J. Leander, C. Parli, 1992, Epilepsia.

Fluoxetine, a Selective Serotonin‐Uptake Inhibitor, Enhances the Anticonvulsant Effects of Phenytoin, Carbamazepine, and Ameltolide (LY 201116)

J. Leander, 1992, Epilepsia.

GLYX-13, a NMDA Receptor Glycine-Site Functional Partial Agonist, Induces Antidepressant-Like Effects Without ketamine-like Side Effects

P. Stanton, A. Gross, R. Kroes, 2013, Neuropsychopharmacology.

Evaluation of dextromethorphan and carbetapentane as anticonvulsants and N-methyl-d-aspartic acid antagonists in mice

J. Leander, 1989, Epilepsy Research.

Clonidine analgesia and suppression of operant responding: dissociation of mechanism.

J. Leander, P. McCleary, 1981, European journal of pharmacology.

Effects of norepinephrine and serotonin uptake inhibitors on the schedule-controlled behavior of the pigeon

R. B. Carter, J. Leander, J. Leander, 1984, Pharmacology Biochemistry and Behavior.

(3SR,4aRS,6RS,8aRS)-6-[2-(1H-tetrazol-5-yl)ethyl]decahydroisoquinoline-3 - carboxylic acid: a structurally novel, systemically active, competitive AMPA receptor antagonist.

P. Ornstein, D. Schoepp, D. Lodge, 1993, Journal of medicinal chemistry.

Discovery and anticonvulsant activity of the potent metabolic inhibitor 4-amino-N-(2,6-dimethylphenyl)-3,5-dimethylbenzamide.

E. Beedle, D. Robertson, C. R. Clark, 1987, Journal of medicinal chemistry.

Use of beta-funaltrexamine to determine mu opioid receptor involvement in the analgesic activity of various opioid ligands.

D. Zimmerman, J. Reel, J. Leander, 1987, The Journal of pharmacology and experimental therapeutics.

A kappa opioid effect: increased urination in the rat.

J. Leander, 1983, The Journal of pharmacology and experimental therapeutics.

Effects of picenadol and its agonist and antagonist isomers on schedule-controlled behavior.

D. Zimmerman, J. Leander, 1983, The Journal of pharmacology and experimental therapeutics.

Further study of kappa opioids on increased urination.

J. Leander, 1983, The Journal of pharmacology and experimental therapeutics.

Fluoxetine suppresses palatability-induced ingestion

J. Leander, 2004, Psychopharmacology.

Effects of a 5-HT1A receptor agonist on acute and delayed cyclophosphamide-induced vomiting.

J. Leander, M. Wolff, 1997, European journal of pharmacology.

Diuresis and suppression of vasopressin by kappa opioids: comparison with mu and delta opioids and clonidine.

R. Zerbe, J. Hart, J. Leander, 1985, The Journal of pharmacology and experimental therapeutics.

Evidence that nalorphine, butorphanol and oxilorphan are partial agonists at a κ-opioid receptor

J. Leander, 1983 .

Effects of full and partial. Kappa agonists and mu agonists on urine output of normally hydrated rats

J. Leander, 1984, Neuropeptides.

Synthesis and pharmacology of a series of 3- and 4-(phosphonoalkyl)pyridine- and -piperidine-2-carboxylic acids. Potent N-methyl-D-aspartate receptor antagonists.

D. Wong, P. Ornstein, J. Deeter, 1989, Journal of medicinal chemistry.

Discovery of a potent, peripherally selective trans-3,4-dimethyl-4-(3-hydroxyphenyl)piperidine opioid antagonist for the treatment of gastrointestinal motility disorders.

J. Gidda, D. Schoepp, B. Cantrell, 1994, Journal of medicinal chemistry.

4-(Tetrazolylalkyl)piperidine-2-carboxylic acids. Potent and selective N-methyl-D-aspartic acid receptor antagonists with a short duration of action.

P. Ornstein, D. Schoepp, D. Lodge, 1991, Journal of medicinal chemistry.

Tetrazole amino acids as competitive NMDA antagonists

P. Ornstein, D. Schoepp, D. Lodge, 1993 .

Selective opioid receptor agonists and antagonists: research tools and potential therapeutic agents.

D. Zimmerman, J. Leander, 1990, Journal of medicinal chemistry.

Structure-activity studies of 6-substituted decahydroisoquinoline-3-carboxylic acid AMPA receptor antagonists. 2. Effects of distal acid bioisosteric substitution, absolute stereochemical preferences, and in vivo activity.

P. Ornstein, D. Schoepp, D. Lodge, 1996, Journal of medicinal chemistry.

3,4-Dimethyl-4-(3-hydroxyphenyl)piperidines: opioid antagonists with potent anorectant activity.

D. Wong, C. Mitch, A. Takemori, 1993, Journal of medicinal chemistry.

Comparing the effects of anileridine, alphaprodine and fentanyl on schedule-controlled responding by pigeons.

J. Leander, 1978, The Journal of pharmacology and experimental therapeutics.

Antiemetic effects of 5-HT1A agonists in the pigeon

J. Leander, M. Wolff, J.David Leander, 1994, Pharmacology Biochemistry and Behavior.

NMDA antagonist activity of (+/-)-(2SR,4RS)-4-(1H-tetrazol-5-ylmethyl)piperidine-2-carboxylic acid resides with the (-)-2R,4S-isomer.

P. Ornstein, D. Schoepp, D. Lodge, 1992, Journal of medicinal chemistry.

Opioid antinociceptive effects of delta-receptor antagonists

J. Leander, L. Mendelsohn, P. Gesellchen, 1988, Pharmacology Biochemistry and Behavior.

GLYX-13, a NMDA Receptor Glycine-Site Functional Partial Agonist, Induces Antidepressant-Like Effects Without Ketamine-Like Side Effects

P. Stanton, A. Gross, R. Kroes, 2013, Neuropsychopharmacology.

GLYX-13, an NMDA receptor glycine site functional partial agonist enhances cognition and produces antidepressant effects without the psychotomimetic side effects of NMDA receptor antagonists

P. Stanton, J. Disterhoft, R. Kroes, 2014, Expert opinion on investigational drugs.

Preparation and anticonvulsant activity of a series of functionalized alpha-heteroatom-substituted amino acids.

H. Kohn, D. Robertson, J. Leander, 1991, Journal of medicinal chemistry.

Metkephamid effects on operant behavior

J. Leander, C. R. Wood, 1982, Peptides.

Effects of ketazocine, ethylketazocine and phenazocine on schedule-controlled behavior: Antagonism by naloxone

J. Leander, 1982, Neuropharmacology.

Modification of behavioral effects of morphine, meperidine and normeperidine by naloxone and by morphine tolerance.

J. Witkin, L. Dykstra, J. Leander, 1983, The Journal of pharmacology and experimental therapeutics.

Effects of narcotic agonists and antagonists on schedule-induced water and morphine ingestion.

L. Harris, D. McMillan, J. Leander, 1975, The Journal of pharmacology and experimental therapeutics.

Synthesis, structure elucidation, and pharmacological evaluation of 5-methyl-oxymorphone (=4,5α-epoxy-3,14-dihydroxy-5,17-dimethylmorphinan-6-one)

D. Schoepp, J. Deeter, N. D. Jones, 1988 .

Oral ingestion of narcotic analgesics by rats.

S. Redding, S. Wallace, T. Wilson, 1976, The Journal of pharmacology and experimental therapeutics.

Kappa Opioid Agonists and Antagonists: Effects on Drinking and Urinary Output

J. Leander, 1984, Appetite.

An analysis of normeperidine's contribution to the rate-decreasing effects of meperidine

J. Leander, 1978, Pharmacology Biochemistry and Behavior.

Subchronic toxicity, metabolism, and pharmacokinetics of the aminobenzamide anticonvulsant ameltolide (LY201116) in rhesus monkeys.

J. Engelhardt, J. Leander, P. Kovach, 1992, Fundamental and applied toxicology : official journal of the Society of Toxicology.

Ethanol and isopropanol effects on schedule-controlled responding

F. W. Ellis, D. McMillan, J. Leander, 1976, Psychopharmacology.

Buprenorphine has potent kappa opioid receptor antagonist activity

J. Leander, 1987, Neuropharmacology.

Antagonism by methysergide of the effects of l-5-hydroxytryptophan and quipazine on schedule-controlled responding

J. Leander, 1981, Neuropharmacology.

Structure-activity studies of 6-(tetrazolylalkyl)-substituted decahydroisoquinoline-3-carboxylic acid AMPA receptor antagonists. 1. Effects of stereochemistry, chain length, and chain substitution.

P. Ornstein, D. Schoepp, D. Lodge, 1996, Journal of medicinal chemistry.

In vitro and in vivo antagonism of AMPA receptor activation by (3s,4ar,6r,8ar)-6-[2-(1(2)h-tetrazole-5-yl)ethyl]decahydroisoquinoline-3-carboxylic acid

P. Ornstein, D. Schoepp, D. Bleakman, 1995, Neuropharmacology.

Phencyclidine‐ type catalepsy in the pigeon: An update on chen's work

L. Dykstra, D. Zimmerman, J. Leander, 1986 .

Opioid antagonists and drinking: Evidence of κ-receptor involvement

J. Leander, M. Hynes, 1983 .

Novel phenylpiperidine opioid antagonists and partial agonists: effects on fluid consumption.

M. Lochner, D. Zimmerman, J. Hart, 1982, European journal of pharmacology.

Attenuating the rate-decreasing effects of phenylpiperidine analgesics by pentobarbital

J. Leander, 1979, Psychopharmacology.

Attenuation of the behavioral effects of meperidine and normeperidine by daily administration of diazepam

J. Leander, 1983, Pharmacology Biochemistry and Behavior.

Meperidine-induced hypothermia in the rat

J. Leander, P. McCleary, 1982, Neuropharmacology.

Chronic chlordiazepoxide and pentobarbital interactions on punished and unpunished behavior.

D. McMillan, J. Leander, 1978, The Journal of pharmacology and experimental therapeutics.

Effect of phenylpiperidine opioid antagonists on food consumption and weight gain of the obese Zucker rat.

C. Mitch, D. Zimmerman, W. Shaw, 1990, The Journal of pharmacology and experimental therapeutics.

Pharmacological profile of LY301317, a potent and selective 5‐HT1A agonist

J. Gidda, R. Fuller, S. Hemrick-Luecke, 1997 .

Differentiation of 5-HT1A receptor ligands by drug discrimination.

J. Leander, M. Wolff, 1997, European journal of pharmacology.

The effect of streptozotocin-induced diabetes on cell proliferation in the rat dentate gyrus

L. Nisenbaum, J. Leander, J.David Leander, 2000, Neuroscience Letters.

Elevation of serum corticosterone in rats by bremazocine, a κ‐opioid agonist

R. Fuller, J. Leander, 1984 .

Elevation of serum corticosterone in rats by bremazocine, a kappa-opioid agonist.

R. Fuller, J. Leander, 1984, The Journal of pharmacy and pharmacology.

m-CPP hypolocomotion is selectively antagonized by compounds with high affinity for 5-HT2C receptors but not 5-HT2A or 5-HT2B receptors

D. Nelson, H. Shannon, V. Lucaites, 2001, Behavioural pharmacology.

Picenadol, a mixed opioid agonist/antagonist without κ opioid agonist activity in the rat urination test

D. Zimmerman, J. Leander, 1983 .

Kappa agonist-induced diuresis: evidence for stereoselectivity, strain differences, independence of hydration variables and a result of decreased plasma vasopressin levels.

R. Zerbe, J. Hart, J. Leander, 1987, The Journal of pharmacology and experimental therapeutics.

Morphological, pharmacokinetic, and hematological studies of lead-exposed pigeons.

C. R. Bagnell, J. Gaynor, D. W. Ross, 1982, Environmental research.

Chronic effects of lead on schedule-controlled pigeon behavior.

D. McMillan, J. Leander, M. Krigman, 1977, Toxicology and applied pharmacology.

Evidence that nalorphine, butorphanol and oxilorphan are partial agonists at a kappa-opioid receptor.

J. Leander, 1983, European journal of pharmacology.

Discriminative stimulus properties of naloxone

R. B. Carter, J. Leander, 2004, Psychopharmacology.

Attenuation of normeperidine's suppressing effect on schedule-controlled behavior.

R. B. Carter, J. Leander, 1982, European journal of pharmacology.

Neuroprotectant effects of LY 274614, a structurally novel systemically active competitive NMDA receptor antagonist

P. Ornstein, D. Schoepp, C. Salhoff, 2005, Journal of Neural Transmission / General Section JNT.

Comparison of the effects of naloxone and picrotoxin on schedule-controlled responding in the pigeon: possible GABA-antagonistic effects of naloxone.

R. B. Carter, J. Leander, 1984, Journal of Pharmacology and Experimental Therapeutics.

Electric shock titration: Effects of meperidine, anileridine and alphaprodine

L. Dykstra, J. Leander, 1978, Pharmacology, Biochemistry and Behavior.

Comparison of morphine, meperidine, anileridine, and alphaprodine on schedule-controlled responding and analgesia

J. Leander, 1980, Pharmacology, Biochemistry and Behavior.

Mazindol effects on schedule-controlled responding of the pigeon.

D. McMillan, J. Leander, 1978, European journal of pharmacology.

Meperidine effects on schedule-controlled responding.

D. McMillan, J. Leander, 1977, The Journal of pharmacology and experimental therapeutics.

Effects of tetrabenazine and phenylpiperidine analgesics during daily clorgyline treatment

J. Leander, 2004, Psychopharmacology.

Interaction of diazepam with meperidine or normeperidine on analgesia and lethality

J. Leander, 1982, Pharmacology Biochemistry and Behavior.

Behavioral effects of phenylpiperidine narcotic antagonists

J. Leander, 1981, Pharmacology Biochemistry and Behavior.

Schedule-induced oral self administration of etonitazene

D. McMillan, J. Leander, 1976, Pharmacology Biochemistry and Behavior.

Schedule-induced narcotic ingestion.

D. McMillan, J. Leander, 1975, Pharmacological reviews.

Schedule-induced oral narcotic self-administration: acute and chronic effects.

L. Harris, D E McMillan, D. McMillan, 1975, The Journal of pharmacology and experimental therapeutics.

Effects of profadol on operant behavior in the pigeon

J. Leander, 1982, Pharmacology Biochemistry and Behavior.

Interactions between naloxone and narcotic analgesics under three schedules that induce polydipsia

D. McMillan, J. Leander, 1976, Pharmacology Biochemistry and Behavior.

Opioid and nonopioid behavioral effects of methadone isomers.

J. Leander, P. McCleary, 1982, The Journal of pharmacology and experimental therapeutics.

Rate-dependent effects of drugs. I. Comparisons of d-amphetamine, pentobarbital and chlorpromazine on multiple and mixed schedules.

D. McMillan, J. Leander, 1974, The Journal of pharmacology and experimental therapeutics.

Olanzapine, an atypical antipsychotic, increases rates of punished responding in pigeons

M. Benvenga, J. Leander, 1995, Psychopharmacology.

Selective Serotonin Reuptake Inhibitors Decrease Impulsive Behavior as Measured by an Adjusting Delay Procedure in the Pigeon

J. Leander, Mary C Wolff, J David Leander, 2002, Neuropsychopharmacology.

The discriminative stimulus properties of LY233708, a selective serotonin reuptake inhibitor, in the pigeon

J. Leander, M. Wolff, 1999, Psychopharmacology.

Selective serotonin reuptake inhibitors potentiate 8-OH-DPAT-induced stimulus control in the pigeon.

J. Leander, M. Wolff, 1998, European journal of pharmacology.

Rate-Dependence and the Effects of Phenothiazine Antipsychotics in Pigeons1

J. Leander, 1981 .

Characteristics of ethanol drinking patterns under schedule-induced polydipsia

F. W. Ellis, D. McMillan, J. Leander, 1976, Psychopharmacology.

Role of peripheral mechanisms in the behavioral effects of 5-hydroxytryptophan

R. B. Carter, L. Dykstra, J. B. Appel, 1978, Pharmacology Biochemistry and Behavior.

Isolation, identification, and synthesis of compounds cosynthesized in the preparation of phencyclidine

R. W. Beaver, J. Leander, L. A. Jones, 1981 .

Synthesis and anticonvulsant activity of 3-aryl-5H-2,3-benzodiazepine ampa antagonists

D. Lodge, M. M. Hansen, J. Leander, 1999 .

Drug discrimination of competitive (CGS-19755) and noncompetitive (phencyclidine) N-methyl- D-aspartic acid antagonists in pigeons

J. Leander, 1989, Pharmacology, Biochemistry and Behavior.

N-Methyl-d-aspartic acid-induced lethality in mice: selective antagonism by phencylidine-like drugs

P. Ornstein, D. Zimmerman, J. Leander, 1988, Brain Research.

Antidepressant-like effect of LY228729 as measured in the rodent forced swim paradigm.

M. Benvenga, J. Leander, 1993, European journal of pharmacology.

Tricyclic antidepressants block N‐methyl‐d‐aspartic acid‐induced lethality in mice

J. Leander, J. David Leander, 1989, British journal of pharmacology.

Evidence for a peripheral effect of serotonin or metabolites in 5-hydroxytryptophan-induced hypothermia

R. B. Carter, J. Leander, 1980, Neuropharmacology.

A comparison of the behavioural effects of 5-HT2A and 5-HT2C receptor agonists in the pigeon

J. Leander, M. Wolff, 2000, Behavioural pharmacology.

Peripheral action of serotonin as a model of depression

J. Leander, 1986, Biological Psychiatry.

N-methyl-D-aspartic acid-induced lethality in mice: selective antagonism by phencyclidine-like drugs.

P. Ornstein, D. Zimmerman, J. Leander, 1988, Brain research.

Behavioral pharmacology of olanzapine: a novel antipsychotic drug.

H. Shannon, N. Moore, M. Benvenga, 1997, The Journal of clinical psychiatry.

Comparison of the antiemetic effects of a 5-HT1A agonist, LY228729, and 5-HT3 antagonists in the pigeon

J. Leander, M. Wolff, 1995, Pharmacology Biochemistry and Behavior.

Opioid agonist and antagonist behavioural effects of buprenorphine

J. Leander, J. David Leander, 1983, British journal of pharmacology.

(3SR,4aRS,6SR,8aRS)-6-(1H-tetrazol-5-yl)decahydroisoquinoline-3-carboxylic acid, a novel, competitive, systemically active NMDA and AMPA receptor antagonist.

P. Ornstein, D. Schoepp, D. Lodge, 1995, Journal of medicinal chemistry.

Preclinical studies on LY228729: a potent and selective serotonin1A agonist.

D. Wong, R. Fuller, D. Nelson, 1993, The Journal of pharmacology and experimental therapeutics.

Pharmacological characterization of enantiomers of 8‐thiomethyl‐2‐(di‐n‐propylamino)tetralin, potent and selective 5‐HT1A receptor agonists

J. Barrett, D. Wong, R. Fuller, 1995 .

Antagonism of oxotremorine-induced behavioral suppression by antimuscarinic drugs

J. Leander, 2004, Psychopharmacology.

Pethidine interaction with clorgyline, pargyline, or 5‐hydroxytryptophan: lack of enhanced pethidine lethality or hyperpyrexia in mice

J. Leander, J. Batten, Gerald W. Hargis, 1978, The Journal of pharmacy and pharmacology.

Pharmacological characterization of LY233053: a structurally novel tetrazole-substituted competitive N-methyl-D-aspartic acid antagonist with a short duration of action.

P. Ornstein, D. Schoepp, D. Lodge, 1990, The Journal of pharmacology and experimental therapeutics.

SR141716A, a cannabinoid CB1 receptor antagonist, improves memory in a delayed radial maze task.

J. Leander, M. Wolff, 2003, European journal of pharmacology.

Effects of piribedil on schedule-controlled responding of the pigeon

J. Leander, 1982, Pharmacology Biochemistry and Behavior.

Drugs and punished responding. V. Effects of drugs on responding suppressed by response-dependent and response-independent electric shock.

D. McMillan, J. Leander, 1975, Archives internationales de pharmacodynamie et de therapie.

The effect of the opioid antagonist LY255582 on body weight of the obese Zucker rat.

D. Zimmerman, W. Shaw, J. Leander, 1991, International journal of obesity.

Effects of naloxone and pentazocine on continuous shock-postponement responding by the pigeon

J. Leander, 1976, Psychopharmacology.

Comparison of two penicillamine-containing enkephalins: Mu, not delta, activity produces analgesia

J. Leander, P. Gesellchen, L. G. Mendelsohn, 1986, Neuropeptides.

m-CPP hypolocomotion is selectively antagonized by compounds with high affinity for 5-HT receptors but not

D. Nelson, H. Shannon, V. Lucaites, 2001 .

Shock intensity and duration interactions on free-operant avoidance behavior.

J. Leander, 1973, Journal of the experimental analysis of behavior.