Ken-ichi Kasahara

发表

Pharmacological profile of a potential anxiolytic: AP159, a new benzothieno-pyridine derivative

T. Nagatani, Tsuneyuki Yamamoto, K. Takao, 2005, Psychopharmacology.

Piezo1 expression increases in rat bladder after partial bladder outlet obstruction.

O. Matsuzaki, Mai Michishita, Ken-ichi Tomita, 2016, Life sciences.

Naftopidil inhibits 5-hydroxytryptamine-induced bladder contraction in rats.

H. Kuriyama, Ken-ichi Tomita, Ken-ichi Kasahara, 2013, European journal of pharmacology.

Decreased Monoamine Oxidase A Expression and Activity in the Bladders of Rats With Partial Outlet Obstruction.

O. Matsuzaki, Mai Michishita, S. Yoshikawa, 2017, Urology.

Mast Cell Accumulation and Degranulation in Rat Bladder with Partial Outlet Obstruction

Mai Michishita, Ken-ichi Tomita, Ken-ichi Kasahara, 2015, Advances in Therapy.

Effects of naftopidil on inhibitory transmission in substantia gelatinosa neurons of the rat spinal dorsal horn in vitro

M. Yoshimura, D. Uta, Ken-ichi Kasahara, 2017, Journal of the Neurological Sciences.

Neural impulse amplitude of taste nerve fiber branches depends on taste receptor sites in bullfrogs

T. Kumazawa, Ken-ichi Kasahara, K. Yoshii, 2014 .

SAR-based optimization of 2-(1H-pyrazol-1-yl)-thiazole derivatives as highly potent EP1 receptor antagonists.

Masakazu Atobe, Ken-ichi Kasahara, M. Kawanishi, 2013, Bioorganic & medicinal chemistry letters.

Hit-to-lead optimization of 2-(1H-pyrazol-1-yl)-thiazole derivatives as a novel class of EP1 receptor antagonists.

Masakazu Atobe, Ken-ichi Kasahara, M. Kawanishi, 2013, Bioorganic & medicinal chemistry letters.

Discovery of 2-(1H-indazol-1-yl)-thiazole derivatives as selective EP(1) receptor antagonists for treatment of overactive bladder by core structure replacement.

Masakazu Atobe, Ken-ichi Kasahara, M. Kawanishi, 2014, Bioorganic & medicinal chemistry letters.

A New Approach for Construction of Quarternary Chiral Centers: Preparation of a-Branched Serine Derivatives

N. Ono, H. Uno, Ken-ichi Kasahara, 2000 .

5-Hydroxytryptamine-induced bladder hyperactivity via the 5-HT2A receptor in partial bladder outlet obstruction in rats.

H. Kuriyama, Ken-ichi Tomita, Ken-ichi Kasahara, 2013, AJP - Renal Physiology.

Role of the central serotonergic system in the anticonflict effect of d-AP159

T. Nagatani, K. Takao, S. Hashimoto, 1992, Pharmacology Biochemistry and Behavior.

The effects of AP521, a novel anxiolytic drug, in three anxiety models and on serotonergic neural transmission in rats.

R. Tsujita, T. Nagatani, K. Takao, 2015, Journal of pharmacological sciences.

Increased expression of 5-HT(2A) and 5-HT(2B) receptors in detrusor muscle after partial bladder outlet obstruction in rats.

O. Matsuzaki, Mai Michishita, Ken-ichi Tomita, 2015, Biomedical research.

Discovery of Novel Indazole Derivatives as Highly Potent and Selective Human β3-Adrenergic Receptor Agonists with the Possibility of Having No Cardiovascular Side Effects.

S. Shuto, Eiichi Tanaka, Ken-ichi Kasahara, 2015, Journal of medicinal chemistry.

Discovery of Novel Indazole Derivatives as Orally Available β3-Adrenergic Receptor Agonists Lacking Off-Target-Based Cardiovascular Side Effects.

T. Hirokawa, S. Shuto, Ken-ichi Kasahara, 2017, Journal of medicinal chemistry.