L. Amori

发表

Synthesis, molecular modeling and preliminary biological evaluation of 1-amino-3-phosphono-3-cyclopentene-1-carboxylic acid and 1-amino-3-phosphono-2-cyclopentene-1-carboxylic acid, two novel agonists of metabotropic glutamate receptors of group III.

F. Gasparini, I. Vranesic, P. Flor, 2000, Bioorganic & medicinal chemistry letters.

Design, synthesis and preliminary evaluation of novel 3'-substituted carboxycyclopropylglycines as antagonists at group 2 metabotropic glutamate receptors.

F. Gasparini, S. Urwyler, P. Flor, 2001, Bioorganic & medicinal chemistry letters.

On the relationship between the two branches of the kynurenine pathway in the rat brain in vivo

R. Schwarcz, P. Guidetti, R. Pellicciari, 2009, Journal of neurochemistry.

Synthesis and preliminary pharmacological evaluation of the four stereoisomers of (2S)-2-(2'-phosphono-3'-phenylcyclopropyl)glycine, the first class of 3'-substituted trans C1'-2'-2-(2'-phosphonocyclopropyl)glycines.

F. Gasparini, P. Flor, G. Costantino, 2007, Bioorganic & medicinal chemistry.

2-Aminonicotinic acid 1-oxides are chemically stable inhibitors of quinolinic acid synthesis in the mammalian brain: a step toward new antiexcitotoxic agents.

R. Schwarcz, G. Costantino, L. Amori, 2013, Journal of medicinal chemistry.

Modulators of the Kynurenine Pathway of Tryptophan Metabolism: Synthesis and Preliminary Biological Evaluation of (S)‐4‐(Ethylsulfonyl)benzoylalanine, a Potent and Selective Kynurenine Aminotransferase II (KAT II) Inhibitor

R. Schwarcz, P. Guidetti, H. Wu, 2006, ChemMedChem.

Design and synthesis of trans-2-substituted-cyclopropane-1-carboxylic acids as the first non-natural small molecule inhibitors of O-acetylserine sulfhydrylase

A. Mozzarelli, B. Campanini, G. Costantino, 2012 .

Sequence Variants in Kynurenine Aminotransferase II (KAT II) Orthologs Determine Different Potencies of the Inhibitor S‐ESBA

R. Schwarcz, R. Pellicciari, A. Macchiarulo, 2008, ChemMedChem.

Indium triflate catalyzed reaction of diisopropyl diazomethylphosphonate with imines as a new approach to cis- and trans-aziridine-2-phosphonates

R. Pellicciari, A. Gioiello, L. Amori, 2007 .

Exploring the metal-catalyzed reaction of furans with alkyl α-diazomethanesulfonate and α-diazomethanephosphonate: synthesis of ω-acyl-substituted sulfono- and phosphonobutadienes

R. Pellicciari, M. Marinozzi, L. Amori, 2009 .

Inhibition of NaV1.6 sodium channel currents by a novel series of 1,4-disubstituted-triazole derivatives obtained via copper-catalyzed click chemistry.

L. Amori, Mirko Rivara, V. Zuliani, 2012, Bioorganic & medicinal chemistry letters.

Synthesis and preliminary biological evaluation of (2S,1'R,2'S)- and (2S,1'S,2'R)-2-(2'-phosphonocyclopropyl)glycines, two novel conformationally constrained l-AP4 analogues.

G. Costantino, R. Pellicciari, C. Thomsen, 2006, Bioorganic & medicinal chemistry letters.

Specific inhibition of kynurenate synthesis enhances extracellular dopamine levels in the rodent striatum

R. Schwarcz, P. Guidetti, H. Wu, 2009, Neuroscience.

Mitochondrial aspartate aminotransferase: a third kynurenate‐producing enzyme in the mammalian brain

R. Schwarcz, P. Guidetti, E. Okuno, 2007, Journal of neurochemistry.

Computational Insights into the Mechanism of Inhibition of OASS‐A by a Small Molecule Inhibitor

G. Costantino, A. Bruno, L. Amori, 2013, Molecular informatics.

Enzymatic transamination of d‐kynurenine generates kynurenic acid in rat and human brain

R. Schwarcz, K. V. Sathyasaikumar, H. Wu, 2012, Journal of neurochemistry.

Addressing the Conformational Flexibility of Serine Racemase by Combining Targeted Molecular Dynamics, Conformational Sampling and Docking Studies

G. Costantino, A. Bruno, L. Amori, 2011, Molecular informatics.

Advances in Design and Development of Sodium Channel Blockers

L. Amori, Mirko Rivara, V. Zuliani, 2011 .

Photooxidation of Benzyl Alcohols Sensitized by TiO2 in CH3CN in the Presence of Ag2SO4. Kinetic Evidence for the Involvement of Adsorption Phenomena

T. D. Giacco, L. Amori, C. Rol, 1998 .

Perinatal kynurenine 3‐hydroxylase inhibition in rodents: Pathophysiological implications

R. Schwarcz, P. Guidetti, R. Pellicciari, 2007, Journal of neuroscience research.

Dysfunctional kynurenine pathway metabolism in the R6/2 mouse model of Huntington’s disease

R. Schwarcz, P. Muchowski, K. V. Sathyasaikumar, 2010, Journal of neurochemistry.

Modulation of the kynurine pathway of tryptophan metabolism in search for neuroprotective agents. Focus on kynurenine-3-hydroxylase.

P. Pevarello, M. Varasi, C. Speciale, 2003, Advances in experimental medicine and biology.

Addressing the Conformational Flexibility of Serine Racemase by Combining Targeted Molecular Dynamics, Conformational Sampling and Docking Studies

G. Costantino, A. Bruno, L. Amori, 2011, Molecular informatics.