J. Ellis

发表

Allosteric Modulation of the M3 Muscarinic Receptor by Amiodarone and N-Ethylamiodarone: Application of the Four-Ligand Allosteric Two-State Model

Edward L. Stahl, G. Elmslie, J. Ellis, 2011, Molecular Pharmacology.

Allostery of atypical modulators at oligomeric G protein-coupled receptors

J. W. Wells, Xi-Ping Huang, Rabindra V Shivnaraine, 2021, Scientific Reports.

Figures and figure supplements Allosteric modulation in monomers and oligomers of a G protein-coupled receptor

J. W. Wells, Yuchong Li, Rabindra V Shivnaraine, 2016 .

Chronic lithium treatment prevents atropine-induced supersensitivity of the muscarinic phosphoinositide response in rat hippocampus

R. Lenox, J. Ellis, 1990, Biological Psychiatry.

Coupling of G Proteins to Reconstituted Monomers and Tetramers of the M2 Muscarinic Receptor*

J. W. Wells, Rabindra V Shivnaraine, O. Ernst, 2014, The Journal of Biological Chemistry.

Novel Allosteric Effects of Amiodarone at the Muscarinic M5 Receptor

Edward L. Stahl, J. Ellis, 2010, Journal of Pharmacology and Experimental Therapeutics.

Critical Amino Acid Residues of the Common Allosteric Site on the M2 Muscarinic Acetylcholine Receptor: More Similarities than Differences between the Structurally Divergent Agents Gallamine and Bis(ammonio)alkane-Type Hexamethylene-bis-[dimethyl-(3-phthalimidopropyl)ammonium]dibromide

Xi-Ping Huang, K. Mohr, J. Ellis, 2005, Molecular Pharmacology.

Interactions of alcuronium, TMB-8, and other allosteric ligands with muscarinic acetylcholine receptors: studies with chimeric receptors.

J. Ellis, M. Seidenberg, 2000, Molecular Pharmacology.

Homologous mutations near the junction of the sixth transmembrane domain and the third extracellular loop lead to constitutive activity and enhanced agonist affinity at all muscarinic receptor subtypes.

D. J. Ford, T. Spalding, E. Burstein, 2002, The Journal of pharmacology and experimental therapeutics.

Muscarinic receptor subtypes in the central nervous system.

W. Hoss, J. Ellis, Wayne Hoss, 1985, International review of neurobiology.

Heterotropic cooperativity within and between protomers of an oligomeric M(2) muscarinic receptor.

J. W. Wells, Xi-Ping Huang, Rabindra V Shivnaraine, 2012, Biochemistry.

Platelet ∝2-adrenergic receptor activity in clinical studies of depression

R. Lenox, J. Peyser, L. Weaver, 1983 .

Competitive and allosteric interactions of 6-chloro-5,10-dihydro-5-[(1-methyl-4-piperidinyl)acetyl]-11H-di benzo[b,e][1, 4]diazepine-11-one hydrochloride (UH-AH 37) at muscarinic receptors, via distinct epitopes.

J. Ellis, M. Seidenberg, 1999, Biochemical pharmacology.

Dronedarone Modulates M1 and M3 Muscarinic Receptors with Subtype Selectivity, Functional Selectivity, and Probe Dependence

E. Burstein, J. Ellis, G. M. Jayasuriya, 2016, Pharmacology.

Muscarinic receptors and second-messenger responses of neurons in primary culture

S. Weiss, J. Ellis, D. Kemp, 1990, Brain Research.

Allosteric Interactions with Muscarinic Acetylcholine Receptors: Complex Role of the Conserved Tryptophan M2422Trp in a Critical Cluster of Amino Acids for Baseline Affinity, Subtype Selectivity, and Cooperativity

K. Mohr, H. Höltje, J. Ellis, 2006, Molecular Pharmacology.

Allosteric site on muscarinic acetylcholine receptors: identification of two amino acids in the muscarinic M2 receptor that account entirely for the M2/M5 subtype selectivities of some structurally diverse allosteric ligands in N-methylscopolamine-occupied receptors.

John Ellis, Kirstin Jöhren, Hans-Dieter Höltje, 2003, Molecular pharmacology.

Receptor‐Coupled Hydrolysis of Phosphoinositides in Rat Hippocampal Slices: Muscarinic Versus Adrenergic

R. Lenox, J. Ellis, D. Hendley, 1987 .

Analysis of regional variations in the affinities of muscarinic agonists in the rat brain

W. Hoss, J. Ellis, 1980, Brain Research.

Muscarinic acetylcholine receptor subtypes: localization and structure/function.

M. Brann, D. Hill-Eubanks, J. Ellis, 1993, Progress in brain research.

Interactions between gallamine and muscarinic receptors: allosterism and subpopulation specificity are separate phenomena.

J. Ellis, M. Seidenberg, 1987, European journal of pharmacology.

Allosteric regulation of cloned m1-m5 muscarinic receptor subtypes.

M. Brann, J. Ellis, J. Huyler, 1991, Biochemical pharmacology.

Allosteric binding sites on muscarinic receptors

J. Ellis, 1997 .

Site-Directed Mutagenesis Implicates a Threonine Residue in TM6 in the Subtype Selectivities of UH-AH 37 and Pirenzepine at Muscarinic Receptors

J. Ellis, M. Seidenberg, 2000, Pharmacology.

Mutational Disruption of a Conserved Disulfide Bond in Muscarinic Acetylcholine Receptors Attenuates Positive Homotropic Cooperativity between Multiple Allosteric Sites and Has Subtype-Dependent Effects on the Affinities of Muscarinic Allosteric Ligands

John Ellis, Xi-Ping Huang, Xi-Ping Huang, 2007, Molecular Pharmacology.

Atypical Muscarinic Allosteric Modulation: Cooperativity between Modulators and Their Atypical Binding Topology in Muscarinic M2 and M2/M5 Chimeric Receptors

U. Holzgrabe, K. Mohr, C. Tränkle, 2005, Molecular Pharmacology.

Allosteric regulation of the binding of [3H]acetylcholine to m2 muscarinic receptors.

J. Ellis, A. Gnagey, 1996, Biochemical pharmacology.

Studies of the Pharmacology, Localization, and Structure of Muscarinic Acetylcholine Receptors a

M. Brann, D. Hill-Eubanks, T. Spalding, 1993, Annals of the New York Academy of Sciences.

Structure/function relationships of muscarinic acetylcholine receptors.

J Ellis, M. Brann, V. Klimkowski, 1993, Life sciences.

Two allosteric modulators interact at a common site on cardiac muscarinic receptors.

J. Ellis, M. Seidenberg, 1992, Molecular pharmacology.

Translocation and Activation of Protein Kinase C in Striatal Neurons in Primary Culture: Relationship to Phorbol Dibutyrate Actions on the Inositol Phosphate Generating System and Neurotransmitter Release

S. Weiss, R. Lenox, J. Ellis, 1989, Journal of neurochemistry.

Desensitization of Muscarinic Receptor‐Coupled Phosphoinositide Hydrolysis in Rat Hippocampus: Comparisons with the α1‐Adrenergic Response

R. Lenox, J. Ellis, D. Hendley, 1988, Journal of neurochemistry.

Characterization of the interactions of gallamine with muscarinic receptors from brain.

R. Lenox, J. Ellis, 1985, Biochemical pharmacology.

Competitive interaction of gallamine with multiple muscarinic receptors.

W. Hoss, J. Ellis, 1982, Biochemical pharmacology.

Chronic lithium administration alters a prominent PKC substrate in rat hippocampus

R. Lenox, J. Patel, D. Watson, 1992, Brain Research.

Muscarinic receptor regulation and protein kinase C: sites for the action of chronic lithium in the hippocampus.

R. Lenox, D. Watson, J. Ellis, 1991, Psychopharmacology bulletin.

Alpha 2-adrenergic receptor-mediated regulation of adenylate cyclase in the intact human platelet. Evidence for a receptor reserve.

R. Lenox, J. Ellis, Y. Ehrlich, 1985, Molecular pharmacology.

Cross-species septal transplants: recovery of choline acetyltransferase activity

J. K. Daniloff, J. Wells, J. Ellis, 1984, Brain Research.

α2-Adrenergic receptors mediate inhibition of cyclic AMP production in neurons in primary culture

S. Weiss, R. Lenox, J. Ellis, 1987, Brain Research.

GTP-preferring protein phosphorylation systems in brain membranes: possible role in adenylate cyclase regulation.

S. Whittemore, R. Lenox, J. Ellis, 1982, Biochemical and biophysical research communications.

Site-directed mutagenesis reveals two epitopes involved in the subtype selectivity of the allosteric interactions of gallamine at muscarinic acetylcholine receptors.

J. Ellis, M. Seidenberg, A. Gnagey, 1999, Molecular pharmacology.

Quaternary forms of classical muscarinic antagonists distinguish subpopulations of muscarinic receptors: correlation with gallamine-defined subpopulations.

R. Lenox, J. Ellis, 1985, Biochemical and biophysical research communications.

Turning induced by unilateral injection of antimicrotubular agents into the substantia nigra

M. Brann, R. Lenox, J. Ellis, 1982, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

Allosteric site on muscarinic acetylcholine receptors: a single amino acid in transmembrane region 7 is critical to the subtype selectivities of caracurine V derivatives and alkane-bisammonium ligands.

K. Mohr, J. Ellis, D. Zlotos, 2002, Molecular pharmacology.

Use of chimeric muscarinic receptors to investigate epitopes involved in allosteric interactions.

M. Brann, J. Ellis, M. Seidenberg, 1993, Molecular pharmacology.

Muscarinic acetylcholine receptor subtypes: localization and structure/function.

M. Brann, D. Hill-Eubanks, J. Ellis, 1993, Progress in brain research.