G. Walker

发表

Allosteric Modulation of the Cannabinoid CB1 Receptor

A. Christopoulos, F. Thomson, R. Pertwee, 2005, Molecular Pharmacology.

Identification of potent, soluble, and orally active TRPV1 antagonists.

Peter Littlewood, J. Maclean, O. Nimz, 2011, Bioorganic & medicinal chemistry letters.

Discovery of potent, soluble and orally active TRPV1 antagonists. Structure-activity relationships of a series of isoxazoles.

M. Ohlmeyer, Peter Littlewood, J. Maclean, 2011, Bioorganic & medicinal chemistry letters.

Org 30029: A New Cardiotonic Agent Possessing Both Phosphodiesterase Inhibitory and Calcium‐Sensitising Properties

M. Shahid, G. Walker, D. Nicholson, 1990 .

Pharmacokinetic optimisation of novel indole-2-carboxamide cannabinoid CB1 antagonists.

M. Deehan, G. Wishart, G. Walker, 2011, Bioorganic & medicinal chemistry letters.

Design, synthesis, and structure–activity relationships of indole-3-carboxamides as novel water soluble cannabinoid CB1 receptor agonists

R. Morphy, J. Tierney, I. Cumming, 2010 .

Design, synthesis, and structure-activity relationship study of conformationally constrained analogs of indole-3-carboxamides as novel CB1 cannabinoid receptor agonists.

G. Walker, Darren Edwards, M. York, 2010, Bioorganic & medicinal chemistry letters.

Structure-activity studies of a novel series of isoxazole-3-carboxamide derivatives as TRPV1 antagonists.

M. Ohlmeyer, J. Maclean, Koc-Kan Ho, 2011, Bioorganic & medicinal chemistry letters.

Design, synthesis, and structure-activity relationship study of bicyclic piperazine analogs of indole-3-carboxamides as novel cannabinoid CB1 receptor agonists.

Glenn Walker, James Baker, Richard Morphy, 2010, Bioorganic & medicinal chemistry letters.

Discovery and SAR of org 24598-a selective glycine uptake inhibitor.

G. Walker, W. Hamilton, J. Clark, 2001, Bioorganic & medicinal chemistry letters.

The identification, and optimisation of hERG selectivity, of a mixed NET/SERT re-uptake inhibitor for the treatment of pain.

R. Morphy, A. Haunsø, D. Buchanan, 2011, Bioorganic & medicinal chemistry letters.

Positive N-methyl-d-aspartate receptor modulation by selective glycine transporter-1 inhibition in the rat dorsal spinal cord in vivo

N. Bowery, G. Walker, D. Hill, 2004, Neuroscience.

The discovery of novel indole-2-carboxamides as cannabinoid CB(1) receptor antagonists.

M. Deehan, G. Wishart, R. Goodwin, 2011, Bioorganic & medicinal chemistry letters.

Design, synthesis and structure-activity relationships of (indo-3-yl) heterocyclic derivatives as agonists of the CB1 receptor. Discovery of a clinical candidate.

R. Bursi, M. Deehan, Paul J. Harradine, 2011, Bioorganic & medicinal chemistry letters.