J. Dodson

发表

Potent and selective small-molecule human urotensin-II antagonists with improved pharmacokinetic profiles.

N. Aiyar, D. Behm, S. Douglas, 2008, Bioorganic & medicinal chemistry letters.

Aminomethylpiperazines as selective urotensin antagonists.

D. Behm, S. Douglas, Zining Wu, 2008, Bioorganic & medicinal chemistry letters.

Palosuran inhibits binding to primate UT receptors in cell membranes but demonstrates differential activity in intact cells and vascular tissues

N. Aiyar, D. Behm, S. Douglas, 2008, British journal of pharmacology.

Discovery of 1-(1,3,5-triazin-2-yl)piperidine-4-carboxamides as inhibitors of soluble epoxide hydrolase.

D. Holt, D. Behm, S. Douglas, 2013, Bioorganic & medicinal chemistry letters.

GSK1562590, a slowly dissociating urotensin‐II receptor antagonist, exhibits prolonged pharmacodynamic activity ex vivo

N. Aiyar, D. Behm, S. Douglas, 2010, British journal of pharmacology.

Prioritizing multiple therapeutic targets in parallel using automated DNA-encoded library screening

Gang Yao, Bing Xia, Jing Chai, 2017, Nature Communications.

The discovery of potent blockers of the canonical transient receptor channels, TRPC3 and TRPC6, based on an anilino-thiazole pharmacophore.

D. Holt, Dwight M. Morrow, R. Willette, 2013, Bioorganic & Medicinal Chemistry Letters.

Development of potent and selective small-molecule human Urotensin-II antagonists.

N. Aiyar, D. Behm, S. Douglas, 2008, Bioorganic & medicinal chemistry letters.

Discovery of soluble epoxide hydrolase inhibitors through DNA-encoded library technology (ELT).

D. Israel, J. Marino, M. Clark, 2021, Bioorganic & medicinal chemistry.

Prioritizing multiple therapeutic targets in parallel using automated DNA-encoded library screening

Robert H Bates, G. Besra, J. Lelièvre, 2017, Nature Communications.