J. H. Busto

发表

Bifunctional Chiral Dehydroalanines for Peptide Coupling and Stereoselective S-Michael Addition.

G. Jiménez‐Osés, C. D. Navo, F. Corzana, 2016, Organic letters.

S-Michael additions to chiral dehydroalanines as an entry to glycosylated cysteines and a sulfa-Tn antigen mimic.

I. Compañón, F. Corzana, Carlos Aydillo, 2014, Journal of the American Chemical Society.

Ring-rearrangement metathesis of 1-substituted 7-azanorbornenes as an entry to 1-azaspiro[4.5]decane systems.

A. Avenoza, J. H. Busto, J. M. Peregrina, 2011, The Journal of organic chemistry.

Quaternary chiral β(2,2)-amino acids with pyridinium and imidazolium substituents.

F. Corzana, A. Avenoza, J. H. Busto, 2012, Chemistry.

Investigations of La Rioja terroir for wine production using 1H NMR metabolomics.

Francesco Savorani, Søren Balling Engelsen, S. Engelsen, 2012, Journal of agricultural and food chemistry.

Solvent-based strategy improves the direct determination of key parameters in edible fats and oils by 1 H NMR.

A. Avenoza, J. H. Busto, J. M. Peregrina, 2019, Journal of the science of food and agriculture.

Time course of the evolution of malic and lactic acids in the alcoholic and malolactic fermentation of grape must by quantitative 1H NMR (qHNMR) spectroscopy.

A. Avenoza, J. H. Busto, J. M. Peregrina, 2006, Journal of agricultural and food chemistry.

A thorough study on the use of quantitative 1H NMR in Rioja red wine fermentation processes.

A. Avenoza, J. H. Busto, J. M. Peregrina, 2009, Journal of agricultural and food chemistry.

Enantiopure synthesis of all four stereoisomers of carbapenam-3-carboxylic acid methyl ester.

A. Avenoza, J. H. Busto, J. M. Peregrina, 2003, The Journal of organic chemistry.

Stereocontrolled ring-opening of a hindered sulfamidate with nitrogen-containing aromatic heterocycles: synthesis of chiral quaternary imidazole derivatives.

G. Jiménez‐Osés, A. Avenoza, J. H. Busto, 2011, The Journal of organic chemistry.

Synthesis and conformational analysis of neoglycoconjugates derived from O- and S-glucose.

F. Corzana, A. Avenoza, J. H. Busto, 2013, Carbohydrate research.

Insights into the geometrical features underlying beta-O-GlcNAc glycosylation: water pockets drastically modulate the interactions between the carbohydrate and the peptide backbone.

G. Jiménez‐Osés, F. Corzana, A. Avenoza, 2009, Chemistry.

Structure-Based Design of Potent Tumor-Associated Antigens: Modulation of Peptide Presentation by Single-Atom O/S or O/Se Substitutions at the Glycosidic Linkage.

R. Fiammengo, G. Jiménez‐Osés, G. Bernardes, 2019, Journal of the American Chemical Society.

Water Sculpts the Distinctive Shapes and Dynamics of the Tumor-Associated Carbohydrate Tn Antigens: Implications for Their Molecular Recognition.

J. A. Fernández, G. Jiménez‐Osés, J. L. Asensio, 2018, Journal of the American Chemical Society.

Molecular Recognition of β‐O‐GlcNAc Glycopeptides by a Lectin‐Like Receptor: Binding Modulation by the Underlying Ser or Thr Amino Acids

G. Joshi, A. P. Davis, F. Corzana, 2011, Chembiochem : a European journal of chemical biology.

α-Methylserinals as an access to α-methyl-β-hydroxyamino acids: application in the synthesis of all stereoisomers of α-methylthreonine

F. Corzana, A. Avenoza, M. M. Zurbano, 2004 .

The Use of Fluoroproline in MUC1 Antigen Enables Efficient Detection of Antibodies in Patients with Prostate Cancer.

S. Nishimura, G. Bernardes, J. L. Asensio, 2017, Journal of the American Chemical Society.

Bioorthogonal Self-Immolative Linker Based on Grob Fragmentation

Xhenti Ferhati, A. Guerreiro, F. Corzana, 2021, Organic letters.

Detection of tumor-associated glycopeptides by lectins: the peptide context modulates carbohydrate recognition.

J. L. Asensio, R. Hurtado-Guerrero, Helena Coelho, 2015, ACS chemical biology.

A domino Michael/Dieckmann process as an entry to α-(hydroxymethyl)glutamic acid.

G. Jiménez‐Osés, Carlos Aydillo, A. Avenoza, 2011, The Journal of organic chemistry.

Evidence of metabolic transformations of amino acids into higher alcohols through (13)C NMR studies of wine alcoholic fermentation.

A. Avenoza, J. H. Busto, J. M. Peregrina, 2010, Journal of agricultural and food chemistry.

Mucin architecture behind the immune response: design, evaluation and conformational analysis of an antitumor vaccine derived from an unnatural MUC1 fragment† †Electronic supplementary information (ESI) available: Characterization of the new compounds, biological assays and MD simulations. See DOI:

M. Wolfert, G. Boons, N. Supekar, 2015, Chemical science.

Synthesis of Nβ-Substituted α,β-Diamino Acids via Stereoselective N-Michael Additions to a Chiral Bicyclic Dehydroalanine.

G. Jiménez‐Osés, C. D. Navo, F. Corzana, 2020, The Journal of organic chemistry.

Synthesis, activity and theoretical study of ABT-418 analogues

C. Cativiela, J. Frigola, A. Avenoza, 2002 .

Towards Enantiomerically Pure Unnatural α-Amino Acids via Photoredox Catalytic 1,4-Additions to a Chiral Dehydroalanine

G. Jiménez‐Osés, C. D. Navo, F. Corzana, 2022, The Journal of organic chemistry.

Synthesis of β2,2-Amino Acids by Stereoselective Alkylation of Isoserine Derivatives Followed by Nucleophilic Ring Opening of Quaternary Sulfamidates

G. Jiménez‐Osés, C. D. Navo, F. Corzana, 2022, The Journal of organic chemistry.

Substituent Effects on the Reactivity of Cyclic Tertiary Sulfamidates.

G. Jiménez‐Osés, C. D. Navo, Nuria Mazo, 2017, The Journal of organic chemistry.

Serine versus threonine glycosylation with α-O-GalNAc: unexpected selectivity in their molecular recognition with lectins.

J. L. Asensio, F. Corzana, V. J. Somovilla, 2014, Chemistry.

Rational design of a Tn antigen mimic.

C. Torres, J. L. Asensio, Y. Sáenz, 2011, Chemical communications.

Engineering O-glycosylation points in non-extended peptides: implications for the molecular recognition of short tumor-associated glycopeptides.

J. L. Asensio, F. Marcelo, F. Corzana, 2011, Chemistry.

SN2 reaction of sulfur nucleophiles with hindered sulfamidates : Enantioselective synthesis of α-methylisocysteine

G. Jiménez‐Osés, A. Avenoza, J. H. Busto, 2006 .

Tn Antigen Mimics Based on sp(2)-Iminosugars with Affinity for an anti-MUC1 Antibody.

G. Jiménez‐Osés, G. Bernardes, C. D. Navo, 2016, Organic letters.

Synthesis of 2-methyl- and 2-methylenecyclobutane amino acids

A. Avenoza, J. H. Busto, J. M. Peregrina, 2005 .

exo-2-Phenyl-7-azabicyclo[2.2.1]heptane-1-carboxylic acid: A new constrained proline analogue

C. Cativiela, A. Avenoza, J. H. Busto, 1995 .

Influence of amino acid stereocenters on the formation of bicyclic N,O-acetals.

G. Jiménez‐Osés, Carlos Aydillo, A. Avenoza, 2014, The Journal of organic chemistry.

Reactivity of (Z)-4-arylidene-5(4H)-oxazolones: [4+2] cycloaddition versus [4+3] cycloaddition/nucleophilic trapping

C. Cativiela, A. Avenoza, J. H. Busto, 2002 .

Cyclobutane amino acid analogues of furanomycin obtained by a formal [2 + 2] cycloaddition strategy promoted by methylaluminoxane.

F. Corzana, A. Avenoza, J. H. Busto, 2010, The Journal of organic chemistry.

Selective Michael-aldol reaction by use of sterically hindered aluminum aryloxides as Lewis acids: an easy approach to cyclobutane amino acids.

A. Avenoza, J. H. Busto, J. M. Peregrina, 2005, Organic letters.

THE USE OF 4-HETARYLIDEN- AND 4-ARYLIDEN-5(4H)-OXAZOLONES AS DIENOPHILES. APPROPRIATE REAGENTS FOR THE SYNTHESIS OF CYCLIC ANALOGUES OF NATURAL AMINO ACIDS

C. Cativiela, A. Avenoza, J. H. Busto, 1997 .

Synthesis of conformationally constrained hydroxy-α-amino acids by intramolecular conjugate addition

C. Cativiela, A. Avenoza, J. H. Busto, 2000, Amino Acids.

Dynamics and Hydration Properties of Small Antifreeze-Like Glycopeptides Containing Non-Natural Amino Acids

F. Corzana, A. Avenoza, J. H. Busto, 2010 .

The nature and sequence of the amino acid aglycone strongly modulates the conformation and dynamics effects of Tn antigen's clusters.

F. Corzana, A. Avenoza, J. H. Busto, 2009, Chemistry.

New synthesis of 7-azabicyclo[2.2.1]heptane-1-carboxylic acid

C. Cativiela, A. Avenoza, J. H. Busto, 2001 .

A biomimetic approach to lanthionines.

G. Jiménez‐Osés, Carlos Aydillo, A. Avenoza, 2012, Organic letters.

α-Alkylation versus retro-O-Michael/γ-alkylation of bicyclic N,O-acetals: an entry to α-methylthreonine

G. Jiménez‐Osés, Carlos Aydillo, A. Avenoza, 2008 .

Design of α-S-Neoglycopeptides Derived from MUC1 with a Flexible and Solvent-Exposed Sugar Moiety.

J. Castro-López, I. Compañón, F. Corzana, 2016, The Journal of organic chemistry.

Selective modification of sulfamidate-containing peptides.

G. Jiménez‐Osés, C. D. Navo, Nuria Mazo, 2020, Organic & biomolecular chemistry.

Mechanistic study of the ring-size modulation in Michael–Dieckmann type reactions of 2-acylaminoacrylates with ketene diethyl acetal

G. Jiménez‐Osés, A. Avenoza, J. H. Busto, 2007 .

Synthesis of 2-amino-1,3-diols incorporating the cyclobutane ring

A. Avenoza, J. H. Busto, J. M. Peregrina, 2008 .

Synthesis of cyclobutane serine analogues.

A. Avenoza, J. H. Busto, J. M. Peregrina, 2005, The Journal of organic chemistry.

Reactivity of 2-acylaminoacrylates with ketene diethyl acetal; [2 + 2] cycloadditions vs. tandem condensations.

A. Avenoza, J. H. Busto, J. M. Peregrina, 2003, Chemical communications.

Asymmetric hetero Diels-Alder as an access to carbacephams.

C. Cativiela, F. Corzana, A. Avenoza, 2002, The Journal of organic chemistry.

Chemoselectivity control in the reactions of 1,2-cyclic sulfamidates with amines.

A. Avenoza, J. H. Busto, J. M. Peregrina, 2013, Chemistry.

Ring‐Rearrangement Metathesis of 7‐Azanorbornenes as an Entry to 1‐Azabicyclo[n.3.0]alkenones

A. Avenoza, J. H. Busto, J. M. Peregrina, 2013 .

A double diastereoselective Michael-type addition as an entry to conformationally restricted tn antigen mimics.

C. D. Navo, F. Corzana, Carlos Aydillo, 2013, The Journal of organic chemistry.

A novel multistep mechanism for the stereocontrolled ring opening of hindered sulfamidates: mild, green, and efficient reactivity with alcohols.

G. Jiménez‐Osés, A. Avenoza, J. H. Busto, 2009, Chemistry.

Diastereoselective synthesis of protected 4-epi-vancosamine from (S)-N-Boc-N,O-isopropylidene-α-methylserinal

F. Corzana, A. Avenoza, M. M. Zurbano, 2003 .

SN2 vs. E2 on quaternary centres: an application to the synthesis of enantiopure beta2,2-amino acids.

G. Jiménez‐Osés, F. Corzana, A. Avenoza, 2004, Chemical communications.

Stabilizing unusual conformations in small peptides and glucopeptides using a hydroxylated cyclobutane amino acid.

Francisco Corzana, Jesús H Busto, Jesús M Peregrina, 2009, Organic & biomolecular chemistry.

Synthesis and conformational analysis of hybrid α/β-dipeptides incorporating S-glycosyl-β(2,2)-amino acids.

G. Jiménez‐Osés, F. Corzana, A. Avenoza, 2015, Chemistry.

Synthesis of enantiopure analogues of 3-hydroxyproline and derivatives

C. Cativiela, A. Avenoza, J. H. Busto, 2002 .

New syntheses of enantiopure 2-methyl isoserines

G. Jiménez‐Osés, F. Corzana, A. Avenoza, 2004 .

Highly chemoselective reactions on hindered sulfamidates with oxygenated nucleophiles

G. Jiménez‐Osés, A. Avenoza, J. H. Busto, 2008 .

β-Turn modulation by the incorporation of c6Ser into Xaa-Pro dipeptide

C. Cativiela, A. Avenoza, J. H. Busto, 2002 .

Toward Enantiomerically Pure β-Seleno-α-amino Acids via Stereoselective Se-Michael Additions to Chiral Dehydroalanines.

G. Jiménez‐Osés, C. D. Navo, F. Corzana, 2020, Organic letters.

Non-natural amino acids as modulating agents of the conformational space of model glycopeptides.

Francisco Corzana, G. Jiménez‐Osés, Gonzalo Jiménez-Osés, 2008, Chemistry.

A VERSATILE AND STEREOSELECTIVE SYNTHESIS OF ()-EPIBATIDINE

C. Cativiela, A. Avenoza, J. H. Busto, 1998 .

Synthesis, conformational analysis and in vivo assays of an anti-cancer vaccine that features an unnatural antigen based on an sp2-iminosugar fragment†

S. Nishimura, J. G. García Fernández, G. Bernardes, 2020, Chemical science.

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J. Oteo, A. Avenoza, J. H. Busto, 2018 .

Understanding the unusual regioselectivity in the nucleophilic ring-opening reactions of gem-disubstituted cyclic sulfates. Experimental and theoretical studies.

F. Corzana, A. Avenoza, J. H. Busto, 2003, The Journal of organic chemistry.

Cell-Penetrating Peptides Containing Fluorescent d-Cysteines.

G. Jiménez‐Osés, J. Cabello, C. D. Navo, 2018, Chemistry.

Deciphering the Non-Equivalence of Serine and Threonine O-Glycosylation Points: Implications for Molecular Recognition of the Tn Antigen by an anti-MUC1 Antibody**

G. Bernardes, J. L. Asensio, J. Castro-López, 2015, Angewandte Chemie.

Conformational analysis of N-boc-N, O-isopropylidene-α-serinals. A combined DFT and NMR study

G. Jiménez‐Osés, F. Corzana, A. Avenoza, 2003 .

Addition of organolithium reagents to Ahc methyl ester. An approach to new α-amino ketones

A. Avenoza, J. H. Busto, J. M. Peregrina, 2002 .

Synthesis of enantiopure (αMe)Dip and other α-methylated β-branched amino acid derivatives

C. Cativiela, A. Avenoza, M. M. Zurbano, 2003 .

Synthesis of Mixed α/β2,2-Peptides by Site-Selective Ring-Opening of Cyclic Quaternary Sulfamidates.

G. Jiménez‐Osés, C. D. Navo, F. Corzana, 2015, Organic letters.

Theoretical evidence for pyramidalized bicyclic serine enolates in highly diastereoselective alkylations.

G. Jiménez‐Osés, Carlos Aydillo, A. Avenoza, 2007, Chemistry.

Synthesis of Fluorescent Lanthipeptide Cytolysin S Analogues by Late-Stage Sulfamidate Ring Opening

W. A. van der Donk, G. Jiménez‐Osés, Imran R. Rahman, 2023, Organic letters.

Applications of 1H Nuclear Magnetic Resonance Spectroscopy in Clinical Microbiology

J. Oteo, J. H. Busto, J. M. Peregrina, 2016 .

Nuclear magnetic resonance applied to antimicrobial drug susceptibility.

J. Oteo, A. Avenoza, J. H. Busto, 2013, Future microbiology.

New insights into alpha-GalNAc-Ser motif: influence of hydrogen bonding versus solvent interactions on the preferred conformation.

Jesús Jiménez-Barbero, Francisco Corzana, G. Jiménez‐Osés, 2006, Journal of the American Chemical Society.

Serine versus threonine glycosylation: the methyl group causes a drastic alteration on the carbohydrate orientation and on the surrounding water shell.

Jesús Jiménez-Barbero, Francisco Corzana, G. Jiménez‐Osés, 2007, Journal of the American Chemical Society.

Monitoring of the Rioja red wine production process by 1 H NMR spectroscopy.

S. Engelsen, F. Savorani, K. Sørensen, 2021, Journal of the science of food and agriculture.

NMR study of histidine metabolism during alcoholic and malolactic fermentations of wine and their influence on histamine production.

A. Avenoza, J. H. Busto, J. M. Peregrina, 2013, Journal of agricultural and food chemistry.

A new efficient synthesis of 2-phenyl-4-oxo-1-amino-cyclohexanecarboxylic acids

C. Cativiela, A. Avenoza, J. H. Busto, 1994 .

Tn Antigen Mimics by Ring-Opening of Chiral Cyclic Sulfamidates with Carbohydrate C1- S- and C1- O-Nucleophiles.

G. Jiménez‐Osés, F. Corzana, Nuria Mazo, 2018, The Journal of organic chemistry.

Role of the countercation in diastereoselective alkylations of pyramidalized bicyclic serine enolates. An easy approach to alpha-benzylserine.

G. Jiménez‐Osés, Carlos Aydillo, A. Avenoza, 2007, The Journal of organic chemistry.

Cyclobutane serine amino acid derivatives as 5-hydroxyproline precursors

A. Avenoza, J. H. Busto, J. M. Peregrina, 2009 .

Effect of beta-O-glucosylation on L-Ser and L-Thr diamides: a bias toward alpha-helical conformations.

Jesús Jiménez-Barbero, Francisco Corzana, S. Engelsen, 2006, Chemistry.

Resolution of (1R,2R)- and (1S,2S)-cyclic constrained phenylalanine analogues (c6Phe). Conformations of (1R,2R)- and (1S,2S)-c6Phe containing peptides

C. Cativiela, A. Avenoza, J. H. Busto, 1998 .

SN2 vs E2 on Quaternary Centers: An Easy Approach to Chiral β2,2-Amino Acids from Cyclic Sulfamidates

G. Jiménez‐Osés, F. Corzana, A. Avenoza, 2005 .

A Convenient Enantioselective Synthesis of (S)-α-Trifluoromethylisoserine

G. Jiménez‐Osés, A. Avenoza, J. H. Busto, 2005 .

Proton Nuclear Magnetic Resonance Spectroscopy as a Technique for Gentamicin Drug Susceptibility Studies with Escherichia coli ATCC 25922

J. Oteo, Y. Sáenz, A. Avenoza, 2015, Journal of Clinical Microbiology.

Preparation and Synthetic Applications of (S)- and (R)-N-Boc-N,O-isopropylidene-α-methylserinals

C. Cativiela, F. Corzana, A. Avenoza, 2004 .

Cyclohexane ring as a tool to select the presentation of the carbohydrate moiety in glycosyl amino acids.

F. Corzana, V. J. Somovilla, A. Avenoza, 2012, Chemistry.

Conformationally-locked C-glycosides: tuning aglycone interactions for optimal chaperone behaviour in Gaucher fibroblasts.

K. Higaki, E. Nanba, C. Ortiz Mellet, 2016, Organic & biomolecular chemistry.

Tn Antigen Mimics Based on sp(2)-Iminosugars with Affinity for an anti-MUC1 Antibody.

G. Bernardes, F. Corzana, V. J. Somovilla, 2016, Organic letters.

Stabilizing unusual conformations in small peptides and glucopeptides using a hydroxylated cyclobutane amino acid.

F. Corzana, A. Avenoza, J. H. Busto, 2009, Organic & biomolecular chemistry.

Stereoselective Synthesis of Orthogonally Protected α-Methylnorlanthionine

A. Avenoza, J. H. Busto, J. M. Peregrina, 2006 .

Stereoselective synthesis of orthogonally protected alpha-methylnorlanthionine.

A. Avenoza, J. H. Busto, J. M. Peregrina, 2006, Organic letters.

A double diastereoselective Michael-type addition as an entry to conformationally restricted tn antigen mimics.

F. Corzana, Carlos Aydillo, A. Avenoza, 2013, The Journal of organic chemistry.

Conformational preferences of chiral acyclic homooligomeric β(2,2)-peptides.

F. Corzana, A. Avenoza, M. M. Zurbano, 2014, Current topics in medicinal chemistry.

Enantioselective synthesis of s-linked glycosyl-β2,2-amino acid derivatives by SN2 reaction with hindered sulfamidates

A. Avenoza, J. H. Busto, J. M. Peregrina, 2006 .