I. Zaganas

发表

Specific characteristics and current diagnostic and treatment modalities performance of super refractory status epilepticus in children: A comparative study.

M. Raissaki, G. Briassoulis, Chrysavgi Stefanogianni, 2022, European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society.

Genetic cause of heterogeneous inherited myopathies in a cohort of Greek patients

S. Erimaki, G. Stavropoulos, P. Mitsias, 2020, Molecular genetics and metabolism reports.

P. Simos, D. Kasselimis, F. Constantinidou, 2014, Journal of the International Neuropsychological Society.

Differential interaction of hGDH1 and hGDH2 with manganese: Implications for metabolism and toxicity

M. Aschner, A. Plaitakis, I. Zaganas, 2015, Neurochemistry International.

Regulation of human glutamate dehydrogenases: Implications for glutamate, ammonia and energy metabolism in brain

A. Plaitakis, I. Zaganas, Ioannis Zaganas, 2001, Journal of neuroscience research.

A Comparison of Acute Hemorrhagic Stroke Outcomes in 2 Populations: The Crete–Boston Study

K. Furie, S. Greenberg, A. Vakis, 2011, Stroke.

Cognitive Impairment and Dementia in Primary Care: Current Knowledge and Future Directions Based on Findings From a Large Cross-Sectional Study in Crete, Greece

P. Simos, A. Vgontzas, C. Tziraki, 2020, Frontiers in Medicine.

Increased incidence of sporadic Creutzfeldt‐Jakob disease on the island of Crete associated with a high rate of PRNP 129‐methionine homozygosity in the local population

T. Sklaviadis, E. Patsouris, C. Haberler, 2001, Annals of neurology.

Study of Alzheimer's disease- and frontotemporal dementia-associated genes in the Cretan Aging Cohort

A. Kanterakis, A. Vgontzas, D. Kafetzopoulos, 2022, Neurobiology of Aging.

Genetic cause of epilepsy in a Greek cohort of children and young adults with heterogeneous epilepsy syndromes

M. Tzardi, P. Vorgia, P. Mitsias, 2021, Epilepsy & behavior reports.

The complex regulation of human glud1 and glud2 glutamate dehydrogenases and its implications in nerve tissue biology

A. Plaitakis, I. Zaganas, C. Spanaki, 2012, Neurochemistry International.

Localization of Human Glutamate Dehydrogenases Provides Insights into Their Metabolic Role and Their Involvement in Disease Processes

K. Michaelidou, I. Zaganas, L. Mathioudakis, 2018, Neurochemical Research.

Pilomotor seizures: an unusual presentation of limbic encephalitis

D. Anyfantakis, E. Symvoulakis, I. Zaganas, 2016, Acta Neurologica Belgica.

Interaction between glutamate dehydrogenase (GDH) and l-leucine catabolic enzymes: Intersecting metabolic pathways

M. M. Islam, S. Hutson, I. Zaganas, 2011, Neurochemistry International.

The effect of pH and ADP on ammonia affinity for human glutamate dehydrogenases

A. Schousboe, H. Waagepetersen, A. Plaitakis, 2013, Metabolic Brain Disease.

The landscape of Mucopolysaccharidosis in Southern and Eastern European countries: a survey from 19 specialistic centers

D. Zafeiriou, Z. Gucev, I. Pećin, 2021, Orphanet Journal of Rare Diseases.

Anti-CV2 associated cerebellar degeneration after complete response to chemoradiation of head and neck carcinoma

D. Mavroudis, V. Georgoulias, A. Plaitakis, 2010, Journal of Neuro-Oncology.

A case of human immunodeficiency virus infection disclosed by cytomegalovirus encephalitis.

D. Kofteridis, I. Zaganas, A. Gikas, 2007, International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases.

Peptide EphB2/CTF2 Generated by the γ-Secretase Processing of EphB2 Receptor Promotes Tyrosine Phosphorylation and Cell Surface Localization of N-Methyl-d-aspartate Receptors*

A. Georgakopoulos, C. Litterst, N. Robakis, 2009, The Journal of Biological Chemistry.

Whole exome sequencing establishes diagnosis of Charcot–Marie–Tooth 4J, 1C, and X1 subtypes

S. Erimaki, P. Mitsias, A. Papadimitriou, 2020, Molecular genetics & genomic medicine.

The p.Pro482Ala Variant in the CNNM2 Gene Causes Severe Hypomagnesemia Amenable to Treatment with Spironolactone

K. Stylianou, I. Petrakis, I. Zaganas, 2022, International journal of molecular sciences.

Import of a major mitochondrial enzyme depends on synergy between two distinct helices of its presequence

K. Tokatlidis, A. Plaitakis, I. Zaganas, 2016, The Biochemical journal.

High Hereditary Transthyretin-Related Amyloidosis Prevalence in Crete

M. Tsilimbaris, P. Mitsias, G. Koutsis, 2022, Neurology: Genetics.

Estrogen Modification of Human Glutamate Dehydrogenases Is Linked to Enzyme Activation State*

A. Plaitakis, V. Mastorodemos, I. Zaganas, 2010, The Journal of Biological Chemistry.

Expression of human GLUD2 glutamate dehydrogenase in human tissues: Functional implications

A. Plaitakis, I. Zaganas, C. Spanaki, 2012, Neurochemistry International.

Human GLUD1 and GLUD2 glutamate dehydrogenase localize to mitochondria and endoplasmic reticulum.

A. Plaitakis, V. Mastorodemos, I. Zaganas, 2009, Biochemistry and cell biology = Biochimie et biologie cellulaire.

Expression of the human isoform of glutamate dehydrogenase, hGDH2, augments TCA cycle capacity and oxidative metabolism of glutamate during glucose deprivation in astrocytes

S. Pääbo, W. Enard, A. Schousboe, 2017, Glia.

The Cretan Aging Cohort: Cohort Description and Burden of Dementia and Mild Cognitive Impairment

N. Fountoulakis, P. Simos, A. Vgontzas, 2018, American journal of Alzheimer's disease and other dementias.

Personalized screening and risk profiles for Mild Cognitive Impairment via a Machine Learning Framework: Implications for general practice

A. Vgontzas, C. Lionis, M. Basta, 2022, Int. J. Medical Informatics.

Basal Cortisol Levels Are Increased in Patients with Mild Cognitive Impairment: Role of Insomnia and Short Sleep Duration.

A. Vgontzas, M. Basta, J. Fernandez-Mendoza, 2022, Journal of Alzheimer's disease : JAD.

The impact of mild cognitive impairment on the self-regulation process: A comparison study of persons with mild cognitive impairment and cognitively healthy older adults

P. Simos, A. Vgontzas, E. Karademas, 2019, Journal of health psychology.

Transgenic Mice Carrying GLUD2 as a Tool for Studying the Expressional and the Functional Adaptation of this Positive Selected Gene in Human Brain Evolution

E. Douni, K. Sidiropoulou, A. Plaitakis, 2018, Neurochemical Research.

The Glutamate Dehydrogenase Pathway and Its Roles in Cell and Tissue Biology in Health and Disease

A. Plaitakis, I. Zaganas, C. Spanaki, 2017, Biology.

Glutamate Dehydrogenase Isoforms with N-Terminal (His)6- or FLAG-Tag Retain Their Kinetic Properties and Cellular Localization

A. Schousboe, L. K. Bak, H. Waagepetersen, 2013, Neurochemical Research.

The human GLUD2 glutamate dehydrogenase: Localization and functional aspects

A. Plaitakis, V. Mastorodemos, I. Zaganas, 2009, Neurochemistry International.

Substitution of Ser for Arg-443 in the Regulatory Domain of Human Housekeeping (GLUD1) Glutamate Dehydrogenase Virtually Abolishes Basal Activity and Markedly Alters the Activation of the Enzyme by ADP and l-Leucine*

M. Karpusas, A. Plaitakis, I. Zaganas, 2002, The Journal of Biological Chemistry.

Side‐chain interactions in the regulatory domain of human glutamate dehydrogenase determine basal activity and regulation

M. Kokkinidis, D. Logothetis, A. Plaitakis, 2015, Journal of neurochemistry.

Molecular basis of human glutamate dehydrogenase regulation under changing energy demands

M. Bessa, A. Plaitakis, V. Mastorodemos, 2005, Journal of neuroscience research.

Crystal structure of glutamate dehydrogenase 2, a positively selected novel human enzyme involved in brain biology and cancer pathophysiology

M. Kokkinidis, V. E. Fadouloglou, I. Sarrou, 2021, Journal of neurochemistry.

Localization of Human Glutamate Dehydrogenases Provides Insights into Their Metabolic Role and Their Involvement in Disease Processes

K. Michaelidou, I. Zaganas, L. Mathioudakis, 2018, Neurochemical Research.

The Odyssey of a Young Gene: Structure–Function Studies in Human Glutamate Dehydrogenases Reveal Evolutionary-Acquired Complex Allosteric Regulation Mechanisms

V. Mastorodemos, I. Zaganas, H. Latsoudis, 2014, Neurochemical Research.

Deregulation of glutamate dehydrogenase in human neurologic disorders

A. Plaitakis, I. Zaganas, C. Spanaki, 2013, Journal of neuroscience research.

Gain-of-function variant in GLUD2 glutamate dehydrogenase modifies Parkinson's disease onset

B. Ritz, S. Papapetropoulos, J. Bronstein, 2010, European Journal of Human Genetics.

Human GLUD2 Glutamate Dehydrogenase Is Expressed in Neural and Testicular Supporting Cells*

K. Kleopa, A. Plaitakis, I. Zaganas, 2010, The Journal of Biological Chemistry.

Mutations in human GLUD2 glutamate dehydrogenase affecting basal activity and regulation

A. Plaitakis, I. Zaganas, H. Latsoudis, 2009, Journal of neurochemistry.

Study of structure–function relationships in human glutamate dehydrogenases reveals novel molecular mechanisms for the regulation of the nerve tissue-specific (GLUD2) isoenzyme

A. Plaitakis, I. Zaganas, C. Spanaki, 2003, Neurochemistry International.

A8344G tRNALys mutation associated with recurrent brain stem stroke-like episodes

P. Vorgia, E. Papadaki, M. Spilioti, 2009, Journal of Neurology.

Cerebrovascular events in inflammatory bowel disease patients treated with anti-tumour necrosis factor alpha agents.

K. Subramaniam, J. Preiß, I. Dotan, 2015, Journal of Crohn's & colitis.

Poor Diet, Long Sleep, and Lack of Physical Activity Are Associated with Inflammation among Non-Demented Community-Dwelling Elderly

A. Vgontzas, M. Yannakoulia, M. Basta, 2022, Healthcare.

Objective Daytime Napping is Associated with Disease Severity and Inflammation in Patients with Mild to Moderate Dementia1.

P. Simos, A. Vgontzas, M. Basta, 2020, Journal of Alzheimer's disease : JAD.

Associations between sleep duration and cognitive impairment in mild cognitive impairment

N. Fountoulakis, P. Simos, A. Vgontzas, 2019, Journal of sleep research.

Opsoclonus-myoclonus syndrome associated with cytomegalovirus encephalitis

N. Xirouchaki, G. Prinianakis, I. Zaganas, 2007, Neurology.

The association of basal cortisol levels with episodic memory in older adults is mediated by executive function

P. Simos, A. Vgontzas, M. Basta, 2022, Neurobiology of Learning and Memory.

Alzheimer's disease research progress in the Mediterranean region: The Alzheimer's Association International Conference Satellite Symposium

M. Carrillo, J. Molinuevo, E. Karageorgiou, 2022, Alzheimer's & dementia : the journal of the Alzheimer's Association.

Linking pesticide exposure and dementia: what is the evidence?

A. Tsatsakis, C. Colosio, M. Wilks, 2013, Toxicology.

Cognitive impairment in a primary healthcare population: a cross-sectional study on the island of Crete, Greece

P. Simos, A. Vgontzas, J. Moschandreas, 2020, BMJ Open.

Genotyping and Plasma/Cerebrospinal Fluid Profiling of a Cohort of Frontotemporal Dementia–Amyotrophic Lateral Sclerosis Patients

V. Kimiskidis, G. Koutsis, G. Karadima, 2021, Brain sciences.

Single Amino Acid Substitution (G456A) in the Vicinity of the GTP Binding Domain of Human Housekeeping Glutamate Dehydrogenase Markedly Attenuates GTP Inhibition and Abolishes the Cooperative Behavior of the Enzyme*

A. Plaitakis, I. Zaganas, 2002, The Journal of Biological Chemistry.

Frequency and risk factors associated with depression in elderly visiting Primary Health Care (PHC) settings: Findings from the Cretan Aging Cohort

P. Simos, A. Vgontzas, C. Lionis, 2021, Journal of Affective Disorders Reports.

Differential expression of glutamate dehydrogenase in cultured neurons and astrocytes from mouse cerebellum and cerebral cortex

A. Schousboe, U. Sonnewald, A Plaitakis, 2001, Journal of neuroscience research.

Transgenic Mice Carrying GLUD2 as a Tool for Studying the Expressional and the Functional Adaptation of this Positive Selected Gene in Human Brain Evolution

E. Douni, K. Sidiropoulou, A. Plaitakis, 2018, Neurochemical Research.

The effect of pH and ADP on ammonia affinity for human glutamate dehydrogenases

A. Schousboe, H. Waagepetersen, A. Plaitakis, 2013, Metabolic Brain Disease.

Association between insomnia symptoms and cognitive impairment in the Cretan Aging Cohort

P. Simos, A. Vgontzas, C. Lionis, 2018, European Geriatric Medicine.

Cognitive screening tools for primary care settings: examining the ‘Test Your Memory’ and ‘General Practitioner assessment of Cognition’ tools in a rural aging population in Greece

P. Simos, A. Vgontzas, C. Tziraki, 2017, The European journal of general practice.

Dent-2 disease with a Bartter-like phenotype caused by the Asp631Glu mutation in the OCRL gene

K. Stylianou, I. Petrakis, I. Zaganas, 2022, BMC Nephrology.

Apolipoprotein E ɛ4 (APOE ɛ4) Allele is Associated with Long Sleep Duration Among Elderly with Cognitive Impairment.

P. Simos, A. Vgontzas, M. Basta, 2020, Journal of Alzheimer's disease : JAD.

IL-6 Enhances the Negative Impact of Cortisol on Cognition among Community-Dwelling Older People without Dementia

A. Vgontzas, M. Basta, I. Zaganas, 2023, Healthcare.

Evidence of Age-Related Hemodynamic and Functional Connectivity Impairment: A Resting State fMRI Study

E. Papadaki, E. Kavroulakis, T. Maris, 2021, Frontiers in Neurology.

Cerebrospinal Fluid TAR DNA-Binding Protein 43 Combined with Tau Proteins as a Candidate Biomarker for Amyotrophic Lateral Sclerosis and Frontotemporal Dementia Spectrum Disorders

I. Evdokimidis, E. Kapaki, G. Paraskevas, 2017, Dementia and Geriatric Cognitive Disorders.

The emerging TDP-43 proteinopathy

E. Kapaki, G. Paraskevas, I. Zaganas, 2018 .

Myelin content changes in probable Alzheimer's disease and mild cognitive impairment: Associations with age and severity of neuropsychiatric impairment

Efrosini Papadaki, Maria Basta, Eleftherios Kavroulakis, 2018, Journal of magnetic resonance imaging : JMRI.

Glutamate Dehydrogenase Isoforms with N-Terminal (His)6- or FLAG-Tag Retain Their Kinetic Properties and Cellular Localization

A. Schousboe, L. K. Bak, H. Waagepetersen, 2013, Neurochemical Research.

Variant transthyretin amyloidosis (ATTRv) polyneuropathy in Greece: a broad overview with a focus on non-endemic unexplored regions of the country

M. Dimopoulos, E. Oikonomou, K. Kleopa, 2021, Neuromuscular Disorders.

Predictors of laterality of motor block during epidural analgesia in a mixed surgical population

N. Tzanakis, D. Korda, I. Zaganas, 2013, Acta anaesthesiologica Scandinavica.

Twist exome capture allows for lower average sequence coverage in clinical exome sequencing

Pieter B. T. Neerincx, Spencer J. Gibson, Farid Yavari Dizjikan, 2023, Human Genomics.

Self-reported fatigue as a risk index for dementia diagnosis

N. Fountoulakis, P. Simos, A. Vgontzas, 2018, European Geriatric Medicine.

Liver Transplantation for Familial Amyloid Polyneuropathy (Val30Met): Long-Term Follow-up Prospective Study in a Nontransplant Center.

M. Tsilimbaris, K. Stylianou, A. Patrianakos, 2019, Transplantation proceedings.

Long-term evaluation of neurological impairment scales after ischemic stroke in type 2 diabetic Caucasians

N. Iacovidou, A. Chalkias, T. Xanthos, 2017 .

Cultural Adaptation, Standardization and Clinical Validity of the Test Your Memory Dementia Screening Instrument in Greek

P. Simos, C. Tziraki, C. Lionis, 2013, Dementia and Geriatric Cognitive Disorders.

Estrogen Modification of Human Glutamate Dehydrogenases Is Linked to Enzyme Activation State*

A. Plaitakis, V. Mastorodemos, I. Zaganas, 2010, The Journal of Biological Chemistry.

Structural Evolution of Primate Glutamate Dehydrogenase 2 as Revealed by In Silico Predictions and Experimentally Determined Structures

M. Kokkinidis, V. E. Fadouloglou, A. Plaitakis, 2023, Biomolecules.

Long-term associations between objective sleep quality and quantity and verbal memory performance in normal cognition and mild cognitive impairment

I. Zaganas, P. Simos, E. Koutentaki, 2023, Frontiers in neuroscience.

Temporal Trends and Associated Factors for Pre-Hospital and In-Hospital Delays of Stroke Patients over a 16-Year Period: The Athens Study

K. Vemmos, N. Iacovidou, T. Xanthos, 2010, Cerebrovascular Diseases.