Xinqun Li

发表

Epidermal growth factor receptor (EGFR) ubiquitination as a mechanism of acquired resistance escaping treatment by the anti-EGFR monoclonal antibody cetuximab.

G. Mills, J. Mendelsohn, Z. Siddik, 2007, Cancer research.

Differential Roles of Phosphoinositide-Dependent Protein Kinase-1 and Akt1 Expression and Phosphorylation in Breast Cancer Cell Resistance to Paclitaxel, Doxorubicin, and Gemcitabine

G. Mills, R. Glazer, K. Liang, 2006, Molecular Pharmacology.

ASCT2 (SLC1A5) is an EGFR-associated protein that can be co-targeted by cetuximab to sensitize cancer cells to ROS-induced apoptosis.

Z. Fan, Yang Lu, Haiquan Lu, 2016, Cancer letters.

Immunoproteomic analysis of the antibody response obtained in mouse following vaccination with a T‐cell vaccine

Xinqun Li, Wen Xu, 2011, Proteomics.

Lumican, a Small Leucine-Rich Proteoglycan, and Its Biological Function in Tumor Progression

J. Fleming, Ya'an Kang, Xinqun Li, 2017 .

Autophosphorylation of Akt at Threonine 72 and Serine 246

G. Mills, K. Liang, Z. Fan, 2006, Journal of Biological Chemistry.

Antineoplastic effects of auranofin in human pancreatic adenocarcinoma preclinical models

J. Fleming, B. Dai, W. Priebe, 2019, Surgery open science.

Requirement of hypoxia-inducible factor-1α down-regulation in mediating the antitumor activity of the anti–epidermal growth factor receptor monoclonal antibody cetuximab

J. Mendelsohn, K. Liang, Z. Fan, 2008, Molecular Cancer Therapeutics.

Neuroprotection by Orexin-A via HIF-1α induction in a cellular model of Parkinson's disease

J. Jankovic, Ye Liu, Xiao-ying Zhu, 2014, Neuroscience Letters.

The epidermal growth factor receptor antibody cetuximab induces autophagy in cancer cells by downregulating HIF-1alpha and Bcl-2 and activating the beclin 1/hVps34 complex.

Z. Fan, Xinqun Li, 2010, Cancer research.

Polysaccharide purified from Polyporus umbellatus (Per) Fr induces the activation and maturation of murine bone-derived dendritic cells via toll-like receptor 4.

Xinqun Li, Jun Chen, Wen Xu, 2010, Cellular immunology.

Oncogenic KRAS recruits an expansive transcriptional network through mutant p53 to drive pancreatic cancer metastasis.

A. Maitra, C. Bristow, M. Barton, 2021, Cancer discovery.

Differential responses to doxorubicin-induced phosphorylation and activation of Akt in human breast cancer cells

K. Liang, Z. Fan, Bolin Liu, 2005, Breast Cancer Research.

Differential Roles of PDK1 and Akt1 Expression and Phosphorylation in Breast Cancer Cell Resistance to Paclitaxel, Doxorubicin, and Gemcitabine Molecular

G. Mills, R. Glazer, K. Liang, 2006 .

3D imaging analysis on an organoid-based platform guides personalized treatment in pancreatic ductal adenocarcinoma

Jeffrey E. Lee, R. DePinho, A. Maitra, 2022, The Journal of clinical investigation.

The association between Parkinson's disease and melanoma

Tianhong Pan, Joseph Jankovic, J. Jankovic, 2011, International journal of cancer.

Genistein potentiates the antitumor effect of 5-Fluorouracil by inducing apoptosis and autophagy in human pancreatic cancer cells.

J. Fleming, Ya'an Kang, R. Suzuki, 2014, Anticancer research.

Neuroprotection of deferoxamine on rotenone-induced injury via accumulation of HIF-1α and induction of autophagy in SH-SY5Y cells

J. Jankovic, W. Le, T. Pan, 2010, Neurochemistry International.

Recombinant human erythropoietin antagonizes trastuzumab treatment of breast cancer cells via Jak2-mediated Src activation and PTEN inactivation.

G. Mills, G. Hortobagyi, M. Hung, 2010, Cancer cell.

Resveratrol-Activated AMPK/SIRT1/Autophagy in Cellular Models of Parkinson's Disease

J. Jankovic, Z. Fan, W. Le, 2011, Neurosignals.

Constitutively active Harvey Ras confers resistance to epidermal growth factor receptor-targeted therapy with cetuximab and gefitinib.

K. Liang, Z. Fan, Yang Lu, 2011, Cancer letters.

Roles of autophagy in cetuximab-mediated cancer therapy against EGFR

Z. Fan, Yang Lu, T. Pan, 2010, Autophagy.

Responses of cancer cells with wild-type or tyrosine kinase domain-mutated epidermal growth factor receptor (EGFR) to EGFR-targeted therapy are linked to downregulation of hypoxia-inducible factor-1α

K. Liang, Z. Fan, Yang Lu, 2007, Molecular Cancer.

DDR1-induced neutrophil extracellular traps drive pancreatic cancer metastasis

M. Katz, J. Fleming, B. Dai, 2020, bioRxiv.

The antiepidermal growth factor receptor monoclonal antibody cetuximab/C225 reduces hypoxia-inducible factor-1 alpha, leading to transcriptional inhibition of vascular endothelial growth factor expression

J. Mendelsohn, Z. Fan, Yang Lu, 2005, Oncogene.

1, 9-Pyrazoloanthrones Downregulate HIF-1α and Sensitize Cancer Cells to Cetuximab-Mediated Anti-EGFR Therapy

Yang Lu, Haiquan Lu, Xinqun Li, 2010, PloS one.

Transforming Growth Factor-β Limits Secretion of Lumican by Activated Stellate Cells within Primary Pancreatic Adenocarcinoma Tumors

Huamin Wang, D. Chatterjee, M. Katz, 2016, Clinical Cancer Research.

Ex Vivo Testing of Patient-Derived Xenografts Mirrors the Clinical Outcome of Patients with Pancreatic Ductal Adenocarcinoma

J. Fleming, B. Dai, Ya'an Kang, 2016, Clinical Cancer Research.

Preclinical Evaluation of Sequential Combination of Oncolytic Adenovirus Delta-24-RGD and Phosphatidylserine-Targeting Antibody in Pancreatic Ductal Adenocarcinoma

J. Gumin, F. Lang, J. Fleming, 2017, Molecular Cancer Therapeutics.

Hypoxia-induced autophagy of stellate cells inhibits expression and secretion of lumican into microenvironment of pancreatic ductal adenocarcinoma

J. Fleming, B. Dai, R. Brekken, 2018, Cell Death & Differentiation.

Rational combination with PDK1 inhibition overcomes cetuximab resistance in head and neck squamous cell carcinoma.

Z. Fan, Yang Lu, Haiquan Lu, 2019, JCI insight.

Compound NSC84167 selectively targets NRF2-activated pancreatic cancer by inhibiting asparagine synthesis pathway

J. Weinstein, J. Fleming, B. Dai, 2021, Cell Death & Disease.

Cetuximab Reverses the Warburg Effect by Inhibiting HIF-1–Regulated LDH-A

Z. Fan, Haiquan Lu, Zhongguang Luo, 2013, Molecular Cancer Therapeutics.

Extracellular Lumican Inhibits Pancreatic Cancer Cell Growth and Is Associated with Prolonged Survival after Surgery

Huamin Wang, D. Chatterjee, M. Katz, 2014, Clinical Cancer Research.

Valproic acid‐mediated Hsp70 induction and anti‐apoptotic neuroprotection in SH‐SY5Y cells

Tianhong Pan, Joseph Jankovic, J. Jankovic, 2005, FEBS letters.

AMPK-mediated energy homeostasis and associated metabolic effects on cancer cell response and resistance to cetuximab

Yang Lu, Z. Fan, Yang Lu, 2015, Oncotarget.

Hypoxia-Induced Autophagy Degrades Stromal Lumican into Tumor Microenvironment of Pancreatic Ductal Adenocarcinoma: A Mini-Review

J. Fleming, Xinqun Li, Bhaswati Sarcar, 2019, Journal of cancer treatment & diagnosis.

Differential responses to doxorubicin-induced phosphorylation and activation of Akt in human breast cancer cells.

K. Liang, Z. Fan, Bolin Liu, 2005, Breast cancer research : BCR.

The epidermal growth factor receptor antibody cetuximab induces autophagy in cancer cells by downregulating HIF-1alpha and Bcl-2 and activating the beclin 1/hVps34 complex.

Z. Fan, Xinqun Li, 2010, Cancer research.

AMPK-mediated energy homeostasis and associated metabolic effects on cancer cell response and resistance to cetuximab

Z. Fan, Yang Lu, Haiquan Lu, 2015, OncoTarget.

The association between Parkinson's disease and melanoma

J. Jankovic, T. Pan, Xinqun Li, 2011, International journal of cancer.

Enhancement of antitumor activity of the anti-EGF receptor monoclonal antibody cetuximab/C225 by perifosine in PTEN-deficient cancer cells

Yiling Lu, K. Liang, Z. Fan, 2006, Oncogene.

Hypoxia-induced autophagy of stellate cells inhibits expression and secretion of lumican into microenvironment of pancreatic ductal adenocarcinoma

J. Fleming, B. Dai, R. Brekken, 2018, Cell Death & Differentiation.