I. Stone

发表

Macrophages and Fc-receptor interactions contribute to the antitumour activities of the anti-CD40 antibody SGN-40

N. Van Rooijen, H. Gerber, C. Law, 2008, British Journal of Cancer.

Potent antitumor activity of the anti-CD19 auristatin antibody drug conjugate hBU12-vcMMAE against rituximab-sensitive and -resistant lymphomas.

P. Carter, F. Hernandez-Ilizaliturri, H. Gerber, 2009, Blood.

SGN-30 Macrophages contribute to the antitumor activity of the anti-CD30 antibody

N. Rooijen, H. Gerber, C. Law, 2013 .

Macrophages contribute to the antitumor activity of the anti-CD30 antibody SGN-30.

N. Van Rooijen, H. Gerber, C. Law, 2007, Blood.

A potent anti-CD70 antibody-drug conjugate combining a dimeric pyrrolobenzodiazepine drug with site-specific conjugation technology.

P. Burke, P. Senter, D. Sussman, 2013, Bioconjugate chemistry.

Tumor-Associated Macrophages Can Contribute to Antitumor Activity through FcγR-Mediated Processing of Antibody–Drug Conjugates

D. Benjamin, M. Jonas, C. Law, 2017, Molecular Cancer Therapeutics.

Characterization of SGN-CD123A, A Potent CD123-Directed Antibody–Drug Conjugate for Acute Myeloid Leukemia

John F. Valliere-Douglass, T. Lewis, Sa A. Wang, 2017, Molecular Cancer Therapeutics.

Engineered anti-CD70 antibody with multiple effector functions exhibits in vitro and in vivo antitumor activities.

P. Carter, A. Wahl, N. Van Rooijen, 2007, Blood.

Development and properties of beta-glucuronide linkers for monoclonal antibody-drug conjugates.

P. Senter, S. Jeffrey, N. Okeley, 2006, Bioconjugate chemistry.

Metabolism of poly-l-glutamic acid (PG) paclitaxel (CT-2103); characterization of metabolites generated through proteolysis by lysosomal cathepsin B

S. Shaffer, J. Singer, Anil Kumar, 2002 .

Effects of Dehydroepiandrosterone Sulfate and Progesterone on Spatial Learning and Memory in Young and Aged Mice

I. Stone, Loraina L. Ghiraldi, K. J. Bodensteiner, 2008, The Journal of general psychology.

271-286 Ghiraldi July 08.indd

I. Stone, Loraina L. Ghiraldi, K. J. Bodensteiner, 2008 .

PAN-TAU ANTIBODY BIIB076 EXHIBITS PROMISING SAFETY AND BIOMARKER PROFILE IN CYNOMOLGUS MONKEY TOXICITY STUDY

G. Cantone, C. Wager, C. Stebbins, 2017, Alzheimer's & Dementia.

Engineered antibody-drug conjugates with defined sites and stoichiometries of drug attachment.

Jennifer B. Webster, Stephen C Alley, P. Carter, 2006, Protein engineering, design & selection : PEDS.

SGN-CD123A, a Pyrrolobenzodiazepine Dimer Linked Anti-CD123 Antibody Drug Conjugate, Demonstrates Effective Anti-Leukemic Activity in Multiple Preclinical Models of AML

John F. Valliere-Douglass, R. Walter, D. Benjamin, 2015 .

SGN-CD33A: a novel CD33-targeting antibody-drug conjugate using a pyrrolobenzodiazepine dimer is active in models of drug-resistant AML.

I. Bernstein, P. Burke, R. Walter, 2013, Blood.

Anti-CD30 diabody-drug conjugates with potent antitumor activity

P. Carter, H. Gerber, S. Alley, 2008, Molecular Cancer Therapeutics.

A coiled-coil masking domain for selective activation of therapeutic antibodies

Matthew R. Levengood, Vivian H. Trang, P. Senter, 2019, Nature Biotechnology.

Dimethyl fumarate increases fetal hemoglobin, provides heme detoxification, and corrects anemia in sickle cell disease.

B. Pace, Biaoru Li, Levi H C Makala, 2017, JCI insight.

Engineered anti-CD70 antibody-drug conjugate with increased therapeutic index

Robert Lyon, Charlotte F. McDonagh, Martha Anderson, 2008, Molecular Cancer Therapeutics.

A coiled-coil masking domain for selective activation of therapeutic antibodies

Matthew R. Levengood, Vivian H. Trang, P. Senter, 2019, Nature Biotechnology.

Proapoptotic signaling activity of the anti-CD40 monoclonal antibody dacetuzumab circumvents multiple oncogenic transformation events and chemosensitizes NHL cells

T. Lewis, J. Drachman, C. Law, 2011, Leukemia.

Potent Anticarcinoma Activity of the Humanized Anti-CD70 Antibody h1F6 Conjugated to the Tubulin Inhibitor Auristatin via an Uncleavable Linker

C. Wood, E. Repasky, H. Gerber, 2008, Clinical Cancer Research.

The Humanized Anti-CD40 Monoclonal Antibody, SGN-40, Potentiates Chemotherapy Regimens in NHL Xenograft Models Via Pro-Apoptotic Signaling.

T. Lewis, H. Gerber, J. Drachman, 2007 .

Optimization of a PEGylated Glucuronide-Monomethylauristatin E Linker for Antibody–Drug Conjugates

P. Burke, P. Senter, Joseph Z. Hamilton, 2016, Molecular Cancer Therapeutics.

SGN-CD33A: A Novel CD33-Directed Antibody-Drug Conjugate, Utilizing Pyrrolobenzodiazepine Dimers, Demonstrates Preclinical Antitumor Activity Against Multi-Drug Resistant Human AML

I. Bernstein, P. Burke, R. Walter, 2012 .

Preclinical Analysis of the Combined Activity of SGN-40, Anti-CD40 Monoclonal Antibody, with Rituximab in Non-Hodgkin Lymphoma.

T. Lewis, H. Gerber, J. Drachman, 2008 .

SGN-CD228A Is an Investigational CD228-Directed Antibody–Drug Conjugate with Potent Antitumor Activity across a Wide Spectrum of Preclinical Solid Tumor Models

A. Nesterova, T. Lewis, N. Okeley, 2023, Molecular cancer therapeutics.

Abstract 4631: Anti-CD70 antibody-drug conjugates containing pyrrolobenzodiazepine dimers demonstrate robust antitumor activity

P. Burke, P. Senter, S. Jeffrey, 2012 .

507 POSTER Potent antitumor activity of the anti-CD19 auristatin antibody-drug conjugate hBU12-vcMMAE in rituximab sensitive and resistant lymphomas

H. Gerber, P. Senter, S. Alley, 2008 .

Development of Novel Quaternary Ammonium Linkers for Antibody–Drug Conjugates

Kim K. Emmerton, A. Waight, P. Burke, 2016, Molecular Cancer Therapeutics.

Abstract 2647: SGN-CD70A, a novel and highly potent anti-CD70 ADC, induces double-strand DNA breaks and is active in models of MDR+ renal cell carcinoma (RCC) and non-Hodgkin lymphoma (NHL)

A. Nesterova, T. Lewis, Martha E. Anderson, 2014 .

SGN-35, an Anti-CD30 Antibody-Drug Conjugate, Exhibits Potent Antitumor Activity for the Treatment of CD30+ Malignancies.

A. Wahl, Michael M C Sun, C. Cerveny, 2005 .

Dimethyl fumarate increases fetal hemoglobin, provides heme detoxification, and corrects anemia in sickle cell disease.

B. Pace, Biaoru Li, Levi H C Makala, 2017, JCI insight.

A potent anti-CD70 antibody-drug conjugate combining a dimeric pyrrolobenzodiazepine drug with site-specific conjugation technology.

P. Burke, P. Senter, D. Sussman, 2013, Bioconjugate chemistry.

Humanized anti-CD19 auristatin antibody-drug conjugates display potent antitumor activity in preclinical models of B-cell malignancies

Damon L. Meyer, P. Carter, H. Gerber, 2007 .