Chunyang Jin

发表

Structural and functional characterization of MBS301, an afucosylated bispecific anti-HER2 antibody

Jian-nan Feng, B. Shen, Xia-Lu Fan, 2018, mAbs.

Selective fluorescence detection of divalent and trivalent metal ions with functionalized lipid membranes.

D. Sasaki, J. Shelnutt, Yujiang Song, 2005 .

Stereospecific Inhibition of Ethanol Potentiation on Glycine Receptor by M554 Stereoisomers

Pilar A. Vásquez, Felipe Vidal, F. Cayuman, 2020, J. Chem. Inf. Model..

Evaluation of Amide Bioisosteres Leading to 1,2,3-Triazole Containing Compounds as GPR88 Agonists: Design, Synthesis, and Structure-Activity Relationship Studies.

Lucas T. Laudermilk, B. Kieffer, E. Darcq, 2021, Journal of medicinal chemistry.

Effect of Substitution on the Aniline Moiety of the GPR88 Agonist 2-PCCA: Synthesis, Structure-Activity Relationships, and Molecular Modeling Studies.

B. Blough, Chunyang Jin, D. Harris, 2016, ACS chemical neuroscience.

Synthesis and receptor binding properties of 2beta-alkynyl and 2beta-(1,2,3-triazol)substituted 3beta-(substituted phenyl)tropane derivatives.

H. Navarro, F. Carroll, Chunyang Jin, 2008, Bioorganic & medicinal chemistry.

Synthesis and Receptor Binding Properties of 2 β -Alkynyl and 2 β -(1,2,3-Triazol)substituted 3 β -(substituted phenyl)tropane Derivatives

H. Navarro, F. Carroll, Chunyang Jin, 2008 .

Discovery of a Potent, Selective, and Brain-Penetrant Small Molecule that Activates the Orphan Receptor GPR88 and Reduces Alcohol Intake.

B. Kieffer, E. Darcq, J. Besheer, 2018, Journal of medicinal chemistry.

Synthesis, pharmacological characterization, and structure-activity relationship studies of small molecular agonists for the orphan GPR88 receptor.

Xi-Ping Huang, B. Roth, X. Zhang, 2014, ACS chemical neuroscience.

Discovery of N-{4-[(3-hydroxyphenyl)-3-methylpiperazin-1-yl]methyl-2-methylpropyl}-4-phenoxybenzamide analogues as selective kappa opioid receptor antagonists.

I. Carroll, James B. Thomas, S. Runyon, 2013, Journal of medicinal chemistry.

Synthesis of ether-linked fluorocarbon surfactants and their aggregational properties in organic solvents.

D. Derzon, D. Sasaki, M. Dugger, 2004, Journal of colloid and interface science.

Development of 3-phenyltropane analogues with high affinity for the dopamine and serotonin transporters and low affinity for the norepinephrine transporter.

H. Navarro, F. Carroll, Chunyang Jin, 2008, Journal of medicinal chemistry.

Synthesis of Carnosine-d7 and Anserine-d4 for Use as Internal Standards in Liquid Chromatography–Mass Spectrometry

Chunyang Jin, K. Rehder, M. Gopinathan, 2009 .

Reversal of Ethanol-induced Intoxication by a Novel Modulator of Gβγ Protein Potentiation of the Glycine Receptor*

J. Fuentealba, L. Aguayo, Gonzalo Yevenes, 2016, The Journal of Biological Chemistry.

Synthesis of N6-[endo-2'-(endo-5'-Hydroxy)norbornyl]-8-(N-methylisopropylamino)-9-methyladenine (WRC-0571): A potent and selective adenosine A1 receptor antagonist

Chunyang Jin, G. Brine, J. Burgess, 2007 .

Intramolecular cyclization reactions of carbonyl derivatives of hydroxysulfones

Chunyang Jin, H. Jacobs, A. Gopalan, 2002 .

Convenient Synthesis of Tolcapone, a Selective Catechol‐O‐methyltransferase Inhibitor

G. Manikumar, Chunyang Jin, K. Rehder, 2008 .

Design, Synthesis, and Structure-Activity Relationship Studies of (4-Alkoxyphenyl)glycinamides and Bioisosteric 1,3,4-Oxadiazoles as GPR88 Agonists.

Lucas T. Laudermilk, B. Kieffer, E. Darcq, 2020, Journal of medicinal chemistry.

Synthesis and structure-activity relationship of 3beta-(4-alkylthio, -methylsulfinyl, and -methylsulfonylphenyl)tropane and 3beta-(4-alkylthiophenyl)nortropane derivatives for monoamine transporters.

F. Ivy Carroll, H. Navarro, Chunyang Jin, 2009, Bioorganic & medicinal chemistry.

Topoisomerase I (Top1): a major target of FL118 for its antitumor efficacy or mainly involved in its side effects of hematopoietic toxicity?

B. Xu, Fengzhi Li, D. Westover, 2017, American journal of cancer research.

FL118, a novel camptothecin derivative, is insensitive to ABCG2 expression and shows improved efficacy in comparison with irinotecan in colon and lung cancer models with ABCG2-induced resistance

M. Del Rio, C. Gongora, Fengzhi Li, 2015, Molecular Cancer.

Copper-catalyzed cyclization of steroidal acylaminoacetylenes: syntheses of novel 11beta-aryl-17,17- spiro[(4'H,5'-methylene)oxazol]-substituted steroids.

C. Cook, Chunyang Jin, J. Kepler, 2007, Organic letters.

Synthesis and identification of novel 11beta-aryl-4',5'-dihydrospiro[estra-4,9-diene-17beta,4'-oxazole] analogs with dissociated antiprogesterone activities.

G. Allan, S. Lundeen, Z. Sui, 2007, Bioorganic & medicinal chemistry letters.

Synthesis and antihormonal properties of novel 11β-benzoxazole-substituted steroids.

S. Fix, C. Cook, Chunyang Jin, 2012, Bioorganic & medicinal chemistry letters.

Discovery and Characterization of the First Nonpeptide Antagonists for the Relaxin-3/RXFP3 System.

J. Besheer, Chunyang Jin, E. Gay, 2022, Journal of medicinal chemistry.

New intramolecular alkylation and Michael addition reactions of hydroxysulfone derivatives—stereoselective preparation of functionalized cyclic ethers

Chunyang Jin, H. Jacobs, A. Gopalan, 2000 .

Indole-Containing Amidinohydrazones as Nonpeptide, Dual RXFP3/4 Agonists: Synthesis, Structure-Activity Relationship, and Molecular Modeling Studies.

C. Zhan, Chunyang Jin, A. Decker, 2021, Journal of medicinal chemistry.

Design, synthesis, and estrogenic activity of a novel estrogen receptor modulator--a hybrid structure of 17beta-estradiol and vitamin E in hippocampal neurons.

R. Brinton, Zisu Mao, Liqin Zhao, 2007, Journal of medicinal chemistry.

Chiral non-racemic dihydroxysulfones via hydrolytic kinetic resolutions—synthesis of oxacyclic ring systems using intramolecular acylation strategies

Chunyang Jin, A. Gopalan, R. D. Ramirez, 2001 .

Synthesis and monoamine transporter binding properties of 2beta-[3'-(substituted benzyl)isoxazol-5-yl]- and 2beta-[3'-methyl-4'-(substituted phenyl)isoxazol-5-yl]-3beta-(substituted phenyl)tropanes.

H. Navarro, F. Carroll, Chunyang Jin, 2008, Bioorganic & medicinal chemistry.

FL118, a novel camptothecin derivative, is insensitive to ABCG2 expression and shows improved efficacy in comparison with irinotecan in colon and lung cancer models with ABCG2-induced resistance

M. Del Rio, C. Gongora, Fengzhi Li, 2015, Molecular Cancer.

The GPR88 agonist RTI‐13951‐33 reduces alcohol drinking and seeking in mice

B. Kieffer, E. Darcq, S. Ben Hamida, 2022, Addiction biology.

Improvement of the Metabolic Stability of GPR88 Agonist RTI-13951-33: Design, Synthesis, and Biological Evaluation.

E. Darcq, S. Ben Hamida, R. Maitra, 2023, Journal of medicinal chemistry.

Synthesis and pharmacological validation of a novel radioligand for the orphan GPR88 receptor.

E. Darcq, C. Kormos, Chunyang Jin, 2022, Bioorganic & medicinal chemistry letters.

The GPR88 receptor agonist 2-PCCA does not alter the behavioral effects of methamphetamine in rats.

Chunyang Jin, Jun-Xu Li, D. Thorn, 2013, European journal of pharmacology.

Practical Synthesis of p‐Aminophenethylspiperone (NAPS), a High‐Affinity, Selective D2‐Dopamine Receptor Antagonist

A. Lewin, Chunyang Jin, G. Brine, 2008 .

Chemical synthesis and structural elucidation of a new serotonin metabolite: (4R)-2-[(5′-hydroxy-1′H-indol-3′-yl)methyl]thiazolidine-4-carboxylic acid

Chunyang Jin, G. Brine, J. Burgess, 2006 .