C. Ochsenbauer

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Potent In Vivo NK Cell-Mediated Elimination of HIV-1-Infected Cells Mobilized by a gp120-Bispecific and Hexavalent Broadly Neutralizing Fusion Protein

J. Kappes, Wei Li, D. Dimitrov, 2017, Journal of Virology.

Complement activation by HIV-1-infected cells: the role of transmembrane glycoprotein gp41.

U. Krüger, M. Dierich, J. Patsch, 1997, Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association.

Bispecific antibodies directed to CD4 domain 2 and HIV envelope exhibit exceptional breadth and picomolar potency against HIV-1

D. Ho, J. Yu, D. Oren, 2013, Proceedings of the National Academy of Sciences.

Multispecific anti-HIV duoCAR-T cells display broad in vitro antiviral activity and potent in vivo elimination of HIV-infected cells in a humanized mouse model

J. Kappes, D. Dimitrov, R. Orentas, 2019, Science Translational Medicine.

Buprenorphine Increases HIV-1 Infection In Vitro but Does Not Reactivate HIV-1 from Latency

Yeseul Kim, Lucia Vojtech, C. Ochsenbauer, 2021, Viruses.

Deficient synthesis of class-switched, HIV-neutralizing antibodies to the CD4 binding site and correction by electrophilic gp120 immunogen

Y. Nishiyama, R. Massey, S. Gorantla, 2014, AIDS.

Association of HIV-1 Envelope-Specific Breast Milk IgA Responses with Reduced Risk of Postnatal Mother-to-Child Transmission of HIV-1

H. Liao, G. Ferrari, Gerald Tegha, 2015, Journal of Virology.

Characterization of immune cells and infection by HIV in human ovarian tissues

C. Wira, M. Rodriguez-Garcia, C. Ochsenbauer, 2017, American journal of reproductive immunology.

Impact of HIV-1 Backbone on Neutralization Sensitivity: Neutralization Profiles of Heterologous Envelope Glycoproteins Expressed in Native Subtype C and CRF01_AE Backbone

Jerome H. Kim, J. Kappes, D. Montefiori, 2013, PloS one.

The transcriptome of HIV-1 infected intestinal CD4+ T cells exposed to enteric bacteria

J. Kappes, M. McCarter, T. Phang, 2017, PLoS pathogens.

Innate immune regulation in HIV latency models

Leanne S. Whitmore, M. Gale, Jennifer Tisoncik-Go, 2022, Retrovirology.

Estradiol Reduces Susceptibility of CD4+ T Cells and Macrophages to HIV-Infection

Sarah G. Crist, J. Fahey, C. Wira, 2013, PloS one.

EpitheliumRectal Mucosa and Model Colonic HIV Type 1 Transcytosis through Human GP41-Specific Antibody Blocks Cell-Free

J. Kappes, M. Bomsel, Ernesto R. Drelichman, 2010 .

The Rous Sarcoma Virus Env Glycoprotein Contains a Highly Conserved Motif Homologous to Tyrosine-Based Endocytosis Signals and Displays an Unusual Internalization Phenotype

C. Ochsenbauer, E. Hunter, S. R. Dubay, 2000, Molecular and Cellular Biology.

Supplemental Information Mass Cytometric Analysis of HIV Entry , Replication , and Remodeling in Tissue CD 4 + T Cells

Gourab Mukherjee, W. Greene, J. McCune, 2022 .

Neutrophil extracellular traps prevent HIV infection in the female genital tract

C. Wira, M. Rodriguez-Garcia, C. Ochsenbauer, 2018, Mucosal Immunology.

Incomplete Downregulation of CD4 Expression Affects HIV-1 Env Conformation and Antibody-Dependent Cellular Cytotoxicity Responses

J. Kappes, J. Richard, J. Prévost, 2018, Journal of Virology.

Analysis of vif-defective human immunodeficiency virus type 1 (HIV-1) virions synthesized in 'non-permissive' T lymphoid cells stably infected with selectable HIV-1.

T. Wilk, V. Bosch, C. Ochsenbauer, 1997, The Journal of general virology.

1 of 40 Characterization of anatomically compartmentalized plasma and milk simian 1 immunodeficiency virus variants in chronically infected African green monkeys.

S. Chow, Joshua D. Amos, G. Fouda, 2016 .

Dendritic Cells from the Human Female Reproductive Tract Rapidly Capture and respond to HIV

J. Kappes, M. Ackerman, Austin W Boesch, 2016, Mucosal Immunology.

Changes in concentrations of cervicovaginal immune mediators across the menstrual cycle: a systematic review and meta-analysis of individual patient data

Hugo A. Wefer, Melis N. Anahtar, R. J. Hayes, 2020, BMC Medicine.

Innate Immunity in the Vagina (Part II): Anti‐HIV Activity and Antiviral Content of Human Vaginal Secretions

J. Fahey, C. Wira, M. Ghosh, 2014, American journal of reproductive immunology.

Optimization and validation of a neutralizing antibody assay for HIV-1 in A3R5 cells.

X. Daniell, J. Kappes, D. Montefiori, 2014, Journal of immunological methods.

Initial HIV-1 Antigen-Speciﬁc CD8 (cid:1) T Cells in Acute HIV-1 Infection Inhibit Transmitted/Founder Virus Replication

H. Ding, J. Kappes, J. Crump, 2012 .

Female genital tract shedding of HIV-1 is rare in women with suppressed HIV-1 in plasma.

A. Adimora, K. Anastos, R. Swanstrom, 2020, AIDS.

Short-Chain Fatty Acids Impair Neutrophil Antiviral Function in an Age-Dependent Manner

A. Panda, F. Carrillo-Salinas, M. Rodriguez-Garcia, 2022, Cells.

Dynamic Antibody Specificities and Virion Concentrations in Circulating Immune Complexes in Acute to Chronic HIV-1 Infection

Feng Gao, David C Montefiori, Frederik Graw, 2011, Journal of Virology.

In Vivo Activation of Human NK Cells by Treatment with an Interleukin-15 Superagonist Potently Inhibits Acute In Vivo HIV-1 Infection in Humanized Mice

J. Kappes, H. Wong, C. Church, 2015, Journal of Virology.

Rectal and vaginal tissue from intravenous VRC01 recipients show protection against ex vivo HIV-1 challenge.

S. Hammer, M. McElrath, I. Frank, 2021, The Journal of clinical investigation.

Rectal tissue and vaginal tissue from intravenous VRC01 recipients show protection against ex vivo HIV-1 challenge

S. Hammer, M. McElrath, I. Frank, 2021 .

Casp8p41 generated by HIV protease kills CD4 T cells through direct Bak activation

J. Kappes, Y. Pang, S. Kaufmann, 2014, Journal of Cell Biology.

Detection of the HIV-1 Accessory Proteins Nef and Vpu by Flow Cytometry Represents a New Tool to Study Their Functional Interplay within a Single Infected CD4+ T Cell

J. Kappes, F. Kirchhoff, B. Hahn, 2021, bioRxiv.

Phenotypic properties of transmitted founder HIV-1

Feng Gao, Bette Korber, Hui Li, 2013, Proceedings of the National Academy of Sciences.

Tetherin-driven adaptation of Vpu and Nef function and the evolution of pandemic and nonpandemic HIV-1 strains.

G. Learn, J. Kappes, P. Sharp, 2009, Cell host & microbe.

High‐throughput quantitative analysis of HIV‐1 and SIV‐specific ADCC‐mediating antibody responses

J. Kappes, B. Haynes, J. Hoxie, 2011, Cytometry. Part A : the journal of the International Society for Analytical Cytology.

Macrophage Infection via Selective Capture of HIV-1-Infected CD4+ T Cells

J. Kappes, Q. Sattentau, D. Kaufmann, 2014, Cell host & microbe.

GP41-Specific Antibody Blocks Cell-Free HIV Type 1 Transcytosis through Human Rectal Mucosa and Model Colonic Epithelium

J. Kappes, M. Bomsel, Ernesto R. Drelichman, 2010, The Journal of Immunology.

HIV-1 Expressing the Envelopes of Transmitted/Founder or Control/Reference Viruses Have Similar Infection Patterns of CD4 T-Cells in Human Cervical Tissue Ex Vivo

J. Kappes, J. Grivel, L. Margolis, 2012, PloS one.

Mucosal stromal fibroblasts markedly enhance HIV infection of CD4+ T cells

L. Giudice, R. Greenblatt, W. Greene, 2017, PLoS pathogens.

The Vaginal Acquisition and Dissemination of HIV-1 Infection in a Novel Transgenic Mouse Model Is Facilitated by Coinfection with Herpes Simplex Virus 2 and Is Inhibited by Microbicide Treatment

J. Kappes, B. Herold, P. Kiser, 2015, Journal of Virology.

Potent Functional Antibody Responses Elicited by HIV-I DNA Priming and Boosting with Heterologous HIV-1 Recombinant MVA in Healthy Tanzanian Adults

P. Earl, B. Moss, M. Robb, 2015, PloS one.

Uterine Epithelial Cell Regulation of DC-SIGN Expression Inhibits Transmitted/Founder HIV-1 Trans Infection by Immature Dendritic Cells

J. Kappes, J. Fahey, C. Wira, 2010, PloS one.

Antibody-Dependent Cellular Cytotoxicity (ADCC)-Mediating Antibodies Constrain Neutralizing Antibody Escape Pathway

J. Kappes, D. Montefiori, L. Morris, 2019, Front. Immunol..

ADCC-mediating non-neutralizing antibodies can exert immune pressure in early HIV-1 infection

D. Montefiori, L. Morris, G. Ferrari, 2021, PLoS pathogens.

Elevated HIV Infection of CD4 T Cells in MRKAd5 Vaccine Recipients Due to CD8 T Cells Targeting Adapted Epitopes

J. Carlson, A. Fiore-Gartland, P. Goepfert, 2021, Journal of virology.

Generation of Transmitted/Founder HIV-1 Infectious Molecular Clones and Characterization of Their Replication Capacity in CD4 T Lymphocytes and Monocyte-Derived Macrophages

H. Ding, J. Kappes, B. Haynes, 2011, Journal of Virology.

Replication competent molecular clones of HIV-1 expressing Renilla luciferase facilitate the analysis of antibody inhibition in PBMC.

H. Ding, J. Kappes, D. Montefiori, 2010, Virology.

Sensitization of T cells to CD95-mediated apoptosis by HIV-1 Tat and gp120

P. Krammer, H. Walczak, C. Ochsenbauer, 1995, Nature.

Analysis of protein expression and virus-like particle formation in mammalian cell lines stably expressing HIV-1 gag and env gene products with or without active HIV proteinase.

K. Mergener, H. Kräusslich, H. Gelderblom, 1993, Virology.

High-Throughput Humanized Mouse Models for Evaluation of HIV-1 Therapeutics and Pathogenesis.

J. Kappes, C. Ochsenbauer, H. Goldstein, 2016, Methods in molecular biology.

Mice Transgenic for CD4-Specific Human CD4, CCR5 and Cyclin T1 Expression: A New Model for Investigating HIV-1 Transmission and Treatment Efficacy

J. Kappes, D. Littman, C. Ochsenbauer, 2013, PloS one.

In vivo killing of primary HIV-infected cells by peripheral-injected early memory–enriched anti-HIV duoCAR T cells

J. Kappes, D. Dimitrov, J. Berman, 2022, JCI insight.

Characterization of Near Full-Length Transmitted/Founder HIV-1 Subtype D and A/D Recombinant Genomes in a Heterosexual Ugandan Population (2006–2011)

A. Kamali, P. Kaleebu, J. Salazar-Gonzalez, 2022, Viruses.

Accumulated mutations by 6 months of infection collectively render transmitted/founder HIV-1 significantly less fit.

A. Perelson, H. Ding, J. Kappes, 2019, The Journal of infection.

Relative resistance of HIV-1 founder viruses to control by interferon-alpha

H. Ding, J. Kappes, I. Williams, 2013, Retrovirology.

Accumulated Mutations Cause Significant Fitness Losses and are Associated with Decreased Viral Loads During Early HIV-1 Infection

A. Perelson, H. Ding, J. Kappes, 2019, SSRN Electronic Journal.

Selection of HIV Envelope Strains for Standardized Assessments of Vaccine-Elicited Antibody-Dependent Cellular Cytotoxicity-Mediating Antibodies

Allan C. deCamp, B. Haynes, D. Montefiori, 2021, Journal of virology.

Mucosal Tissue Tropism and Dissemination of HIV-1 Subtype B Acute Envelope-Expressing Chimeric Virus

J. Kappes, Yong Gao, E. Arts, 2012, Journal of Virology.

Sex-specific innate immune selection of HIV-1 in utero is associated with increased female susceptibility to infection

M. Altfeld, J. Kappes, T. Ndung’u, 2020, Nature Communications.

Assessment of a diverse panel of transmitted/founder HIV-1 infectious molecular clones in a luciferase based CD8 T-cell mediated viral inhibition assay

E. Nduati, E. Hunter, L. Yue, 2022, Frontiers in Immunology.

Development of a luciferase based viral inhibition assay to evaluate vaccine induced CD8 T-cell responses.

J. Kappes, O. Anzala, T. Hanke, 2014, Journal of immunological methods.

Primary HIV-1 Strains Use Nef To Downmodulate HLA-E Surface Expression

M. Altfeld, J. Kappes, F. Kirchhoff, 2019, Journal of Virology.

Transmitted/Founder and Chronic Subtype C HIV-1 Use CD4 and CCR5 Receptors with Equal Efficiency and Are Not Inhibited by Blocking the Integrin α4β7

H. Ding, J. Kappes, B. Haynes, 2012, PLoS pathogens.

Initial HIV-1 Antigen-Specific CD8+ T Cells in Acute HIV-1 Infection Inhibit Transmitted/Founder Virus Replication

H. Ding, J. Kappes, B. Haynes, 2012, Journal of Virology.

Dynamic Antibody Speciﬁcities and Virion Concentrations in Circulating Immune Complexes in Acute to Chronic HIV-1 Infection (cid:1) †

A. Perelson, J. Kappes, B. Haynes, 2011 .

Antibody-Dependent Cellular Cytotoxicity against Primary HIV-Infected CD4+ T Cells Is Directly Associated with the Magnitude of Surface IgG Binding

J. Kappes, J. Mascola, C. Hallahan, 2012, Journal of Virology.

Postnatally-transmitted HIV-1 Envelope variants have similar neutralization-sensitivity and function to that of nontransmitted breast milk variants

G. Learn, B. Haynes, D. Montefiori, 2013, Retrovirology.

CD4 regulatory T cells augment HIV-1 expression of polarized M1 and M2 monocyte derived macrophages.

L. Smythies, Mingce Zhang, C. Ochsenbauer, 2017, Virology.

Detection of HIV-1 Neutralizing Antibodies in a Human CD4+/CXCR4+/CCR5+ T-Lymphoblastoid Cell Assay System

Jerome H. Kim, J. Kappes, D. Montefiori, 2013, PloS one.

Infectious Virion Capture by HIV-1 gp120-Specific IgG from RV144 Vaccinees

Jerome H. Kim, H. Liao, J. Kappes, 2013, Journal of Virology.

Virion Capture by HIV-1 gp 120-Specific IgG from RV 144 Vaccinees

Jerome H. Kim, H. Liao, J. Kappes, 2013 .

Differential inhibition of human immunodeficiency virus type 1 in peripheral blood mononuclear cells and TZM-bl cells by endotoxin-mediated chemokine and gamma interferon production.

H. Liao, J. Kappes, B. Haynes, 2010, AIDS research and human retroviruses.

New virologic reagents for neutralizing antibody assays

J. Kappes, C. Ochsenbauer, 2009, Current opinion in HIV and AIDS.

High-Multiplicity HIV-1 Infection and Neutralizing Antibody Evasion Mediated by the Macrophage-T Cell Virological Synapse

J. Kappes, Q. Sattentau, R. Russell, 2013, Journal of Virology.

HIV-1 Neutralizing Antibody Signatures and Application to Epitope-Targeted Vaccine Design

James Theiler, Karina Yusim, S. Gnanakaran, 2019, Cell host & microbe.

An HIV-1 gp120 Envelope Human Monoclonal Antibody That Recognizes a C1 Conformational Epitope Mediates Potent Antibody-Dependent Cellular Cytotoxicity (ADCC) Activity and Defines a Common ADCC Epitope in Human HIV-1 Serum

J. Kappes, B. Haynes, J. Hoxie, 2011, Journal of Virology.

Conformational Epitope Mediates Potent ADCC Activity and Defines a Common 2

J. Kappes, B. Haynes, J. Hoxie, 2011 .

The Role of Natural Killer (NK) Cells and NK Cell Receptor Polymorphisms in the Assessment of HIV-1 Neutralization

J. Kappes, D. Montefiori, N. Michael, 2012, PloS one.

Phenotypic and Functional Profile of HIV-Inhibitory CD8 T Cells Elicited by Natural Infection and Heterologous Prime/Boost Vaccination

J. Kappes, B. Haynes, R. Koup, 2010, Journal of Virology.

Anti-HIV Activity in Cervical-Vaginal Secretions from HIV-Positive and -Negative Women Correlate with Innate Antimicrobial Levels and IgG Antibodies

J. Kappes, Zhijin Wu, K. Mayer, 2010, PloS one.

Dual-Affinity Re-Targeting proteins direct T cell-mediated cytolysis of latently HIV-infected cells.

H. Liao, B. Haynes, D. Montefiori, 2015, The Journal of clinical investigation.

Mass Cytometric Analysis of HIV Entry, Replication, and Remodeling in Tissue CD4+ T Cells.

Gourab Mukherjee, W. Greene, J. McCune, 2017, Cell reports.

Stromal Down-Regulation of Macrophage CD4/CCR5 Expression and NF-κB Activation Mediates HIV-1 Non-Permissiveness in Intestinal Macrophages

J. Kappes, G. Meng, P. Clapham, 2011, PLoS pathogens.

Magnitude and Breadth of the Neutralizing Antibody Response in the RV144 and Vax003 HIV-1 Vaccine Efficacy Trials

Hasan Ahmed, Hongmei Gao, Jaranit Kaewkungwal, 2012, The Journal of infectious diseases.

Global Panel of HIV-1 Env Reference Strains for Standardized Assessments of Vaccine-Elicited Neutralizing Antibodies

Raphael Gottardo, Hongmei Gao, Bette T. Korber, 2013, Journal of Virology.

Unimpaired function of a naturally occurring C terminally truncated vif gene product of human immunodeficiency virus type 1.

V. Bosch, U. Wieland, I. Oelze, 1996, The Journal of general virology.

Superior Efficacy of a Human Immunodeficiency Virus Vaccine Combined with Antiretroviral Prevention in Simian-Human Immunodeficiency Virus-Challenged Nonhuman Primates

Xiaoying Shen, G. Tomaras, R. Shattock, 2016, Journal of Virology.

Neutrophil extracellular traps prevent HIV infection in the female genital tract

C. Wira, M. Rodriguez-Garcia, C. Ochsenbauer, 2018, Mucosal Immunology.

Breadth of CD8 T-cell mediated inhibition of replication of diverse HIV-1 transmitted-founder isolates correlates with the breadth of recognition within a comprehensive HIV-1 Gag, Nef, Env and Pol potential T-cell epitope (PTE) peptide set

E. Hunter, P. Hayes, J. Gilmour, 2021, PloS one.

Synergy in monoclonal antibody neutralization of HIV-1 pseudoviruses and infectious molecular clones

L. Lopalco, A. Venuti, C. Pastori, 2014, Journal of Translational Medicine.

Selective Impact of HIV Disease Progression on the Innate Immune System in the Human Female Reproductive Tract

J. Kappes, K. Mayer, P. Wright, 2012, PloS one.

Optimized Replicating Renilla Luciferase Reporter HIV-1 Utilizing Novel Internal Ribosome Entry Site Elements for Native Nef Expression and Function.

H. Ding, J. Kappes, C. Ochsenbauer, 2015, AIDS research and human retroviruses.

Casp8p41 generated by HIV protease kills CD4 T cells through direct Bak activation

J. Kappes, Y. Pang, S. Kaufmann, 2014, The Journal of cell biology.

Neutralization Takes Precedence Over IgG or IgA Isotype-related Functions in Mucosal HIV-1 Antibody-mediated Protection

H. Liao, Laura L. Sutherland, B. Haynes, 2016, EBioMedicine.

Longitudinal bioluminescent imaging of HIV-1 infection during antiretroviral therapy and treatment interruption in humanized mice

T. Hope, P. Uchil, W. Mothes, 2019, bioRxiv.

Antigenicity and immunogenicity of a novel, acute HIV-1 Tanzanian subtype C gp145 envelope protein for clinical development

S. Zolla-Pazner, E. Sanders-Buell, S. Tovanabutra, 2012, Retrovirology.

Characterization of Simian Immunodeficiency Virus Variants Anatomically Compartmentalized in Plasma and Milk in Chronically Infected African Green Monkeys

S. Chow, Joshua D. Amos, G. Fouda, 2016, Journal of Virology.

Sex-specific innate immune selection of HIV-1 in utero is associated with increased female susceptibility to infection

M. Altfeld, J. Kappes, T. Ndung’u, 2020, Nature Communications.

Antibody-mediated inhibition of HIV-1 elicited by HIV-I DNA priming and boosting with heterologous HIV-1 recombinant MVA in healthy Tanzanian adults

M. Robb, G. Ferrari, A. Joachim, 2012, Retrovirology.

HIV-1 Neutralizing Antibody Signatures and Application to Epitope-Targeted Vaccine Design

G. Learn, P. Hraber, B. Haynes, 2019, Cell host & microbe.

Rectal and vaginal tissue from intravenous VRC01 recipients show protection against ex vivo HIV-1 challenge

M. McElrath, A. McDermott, J. Ledgerwood, 2021 .

In Vivo Activation of Human NK Cells by Treatment with an Interleukin-15 Superagonist Potently Inhibits Acute In Vivo HIV-1 Infection in Humanized Mice

J. Kappes, H. Wong, C. Church, 2015, Journal of Virology.

Dual-Affinity Re-Targeting proteins direct T cell-mediated cytolysis of latently HIV-infected cells.

D. Montefiori, P. Moore, N. Archin, 2015, The Journal of clinical investigation.

High-Multiplicity HIV-1 Infection and Neutralizing Antibody Evasion Mediated by the Macrophage-T Cell Virological Synapse

J. Kappes, Q. Sattentau, R. Russell, 2013, Journal of Virology.

Changes in concentrations of cervicovaginal immune mediators across the menstrual cycle: a systematic review and meta-analysis of individual patient data

Hugo A. Wefer, Melis N. Anahtar, R. J. Hayes, 2022, BMC Medicine.

Detection of the HIV-1 accessory proteins Nef and Vpu by flow cytometry represents a new 1 tool to study their functional interplay within a single infected CD 4 + T cell 2 3

J. Prévost, H. Medjahed, C. Ochsenbauer, 2021 .

High‐throughput quantitative analysis of HIV‐1 and SIV‐specific ADCC‐mediating antibody responses

J. Kappes, B. Haynes, J. Hoxie, 2011, Cytometry. Part A : the journal of the International Society for Analytical Cytology.

J. Kappes, B. Haynes, J. Hoxie, 2011, Journal of Virology.

Association of HIV-1 Envelope-Specific Breast Milk IgA Responses with Reduced Risk of Postnatal Mother-to-Child Transmission of HIV-1

G. Fouda, G. Tomaras, D. Jamieson, 2015, Journal of Virology.