C. Kristensen

发表

Glycoengineering design options for IgG1 in CHO cells using precise gene editing

S. Vakhrushev, H. Clausen, Yang Mao, 2018, Glycobiology.

N-glycosylation increases the circulatory half-life of human growth hormone.

H. Rahbek-Nielsen, H. Clausen, P. Thygesen, 2010, Endocrinology.

Posttranslational N-glycosylation takes place during the normal processing of human coagulation factor VII.

C. Kristensen, G. Bolt, T. Steenstrup, 2005, Glycobiology.

Insulin Interaction with Minimized Receptors and Binding Proteins

A. S. Andersen, C. Kristensen, 2002 .

Expression and Characterization of a 70-kDa Fragment of the Insulin Receptor That Binds Insulin

L. Schäffer, A. S. Andersen, C. Kristensen, 1998, The Journal of Biological Chemistry.

More than one intracellular processing bottleneck delays the secretion of coagulation factor VII

C. Kristensen, G. Bolt, T. Steenstrup, 2008, Thrombosis and Haemostasis.

Protein network reconstruction of CHO cell secretory pathway

M. Andersen, H. F. Kildegaard, A. Lund, 2014 .

Full transcriptome analysis of Chinese Hamster Ovary cell lines producing a dynamic range of Coagulation Factor VIII

M. Andersen, J. Hansen, C. Kaas, 2013, BMC Proceedings.

Specificity of Insulin and Insulin-like Growth Factor I Receptors Investigated using Chimeric Mini-Receptors

A. S. Andersen, C. Kristensen, F. Wiberg, 1999, The Journal of Biological Chemistry.

Role of Insulin Receptor Dimerization Domains in Ligand Binding, Cooperativity, and Modulation by Anti-receptor Antibodies*

K. Siddle, M. Soos, C. Kristensen, 2002, The Journal of Biological Chemistry.

A single-chain insulin-like growth factor I/insulin hybrid binds with high affinity to the insulin receptor.

L. Schäffer, A. S. Andersen, C. Kristensen, 1995, The Biochemical journal.

Functional Reconstitution of Insulin Receptor Binding Site from Non-binding Receptor Fragments*

P. H. Hansen, S. Østergaard, A. S. Andersen, 2002, The Journal of Biological Chemistry.

Structures of insect Imp-L2 suggest an alternative strategy for regulating the bioavailability of insulin-like hormones

J. Wade, A. Brzozowski, J. Turkenburg, 2018, Nature Communications.

Structural Basis of the Aberrant Receptor Binding Properties of Hagfish and Lamprey Insulins

V. Kiselyov, P. Holst, P. De Meyts, 2009, Biochemistry.

Alanine Scanning Mutagenesis of Insulin*

Claus Kristensen, Svend Havelund, D. Steiner, 1997, The Journal of Biological Chemistry.

Correlations of receptor binding and metabolic and mitogenic potencies of insulin analogs designed for clinical use.

L. Schäffer, C. Schmid, C. Kristensen, 2000, Diabetes.

A New Secreted Insect Protein Belonging to the Immunoglobulin Superfamily Binds Insulin and Related Peptides and Inhibits Their Activities*

L. Schäffer, C. Kristensen, Asser Sloth Andersen, 2000, The Journal of Biological Chemistry.

A universal GlycoDesign for lysosomal replacement enzymes to improve circulation time and biodistribution

A. Heck, L. Johannes, R. Desnick, 2023, Frontiers in Bioengineering and Biotechnology.

All post-translational modifications except propeptide cleavage are required for optimal secretion of coagulation factor VII

C. Kristensen, G. Bolt, T. Steenstrup, 2007, Thrombosis and Haemostasis.

Engineered CHO cells for production of diverse, homogeneous glycoproteins

Claus Kristensen, Shamim H Rahman, Carsten Behrens, 2015, Nature Biotechnology.

Network reconstruction of the mouse secretory pathway applied on CHO cell transcriptome data

Christian Schrøder Kaas, Claus Kristensen, Julian Brandl, 2017, BMC Systems Biology.

Toward genome-scale models of the Chinese hamster ovary cells: incentives, status and perspectives

Christian Schrøder Kaas, Claus Kristensen, Mikael Rørdam Andersen, 2014 .

Ligand-induced conformational change in the minimized insulin receptor.

S. Havelund, M. Dunn, N. Kaarsholm, 2000, Journal of molecular biology.

The glycosylation design space for recombinant lysosomal replacement enzymes produced in CHO cells

R. Schiffmann, Yoshiki Narimatsu, E. Bennett, 2019, Nature Communications.

Dimeric Fragment of the Insulin Receptor α-Subunit Binds Insulin with Full Holoreceptor Affinity*

A. S. Andersen, C. Kristensen, Jakob Brandt, 2001, The Journal of Biological Chemistry.

RNA-seq based expression analysis of the CHO cell protein secretion pathway

M. Andersen, H. F. Kildegaard, A. Lund, 2013 .

Sequencing the CHO DXB11 genome reveals regional variations in genomic stability and haploidy

Christian Schrøder Kaas, Claus Kristensen, Mikael Rørdam Andersen, 2015, BMC Genomics.

Deep sequencing reveals different compositions of mRNA transcribed from the F8 gene in a panel of FVIII-producing CHO cell lines.

M. Andersen, J. Hansen, C. Kaas, 2015, Biotechnology journal.

The glycosylation design space for recombinant lysosomal replacement enzymes produced in CHO cells

R. Schiffmann, Yoshiki Narimatsu, E. Bennett, 2019, Nature Communications.

Characterization of Chinese Hamster Ovary Cells Producing Coagulation Factor VIII Using Multi-omics Tools

M. Andersen, C. Kaas, C. Kristensen, 2015 .

Network reconstruction of the mouse secretory pathway applied on CHO cell transcriptome data

M. Andersen, L. Pedersen, H. F. Kildegaard, 2017, BMC Systems Biology.