Shuai Tang

发表

One-pot N-glycosylation remodeling of IgG with non-natural sialylglycopeptides enables glycosite-specific and dual-payload antibody-drug conjugates.

Wei Huang, Yang Yang, Min Huang, 2016, Organic & biomolecular chemistry.

Crassins A-H, Diterpenoids from the Roots of Croton crassifolius.

Min Huang, Wen-qiong Wang, Shuai Tang, 2017, Journal of natural products.

Discovery of Novel IDH1 Inhibitor Through Comparative Structure-Based Virtual Screening

Yuping Tang, Xu Long, Yu-wei Wang, 2020, Frontiers in Pharmacology.

EPHA2 feedback activation limits the response to PDEδ inhibition in KRAS-dependent cancer cells

Min Huang, Jian Ding, M. Geng, 2019, Acta Pharmacologica Sinica.

Jatrophanes as promising multidrug resistance modulators: Advances of structure-activity relationships.

Jun Li, Wen-qiong Wang, Shuai Tang, 2018, Fitoterapia.

Fungal Mycotoxin Penisuloxazin A, A Novel C-terminal Hsp90 Inhibitor and Characteristics of Its Analogues on Hsp90 Function Related to Binding Sites.

Ming Liu, Meilin Zhu, Dehai Li, 2020, Biochemical pharmacology.

Design, synthesis and biological evaluation of tetrahydronaphthyridine derivatives as bioavailable CDK4/6 inhibitors for cancer therapy.

M. Huang, Min Huang, Yi Chen, 2018, European journal of medicinal chemistry.

Discovery of Novel Drug-like PHGDH Inhibitors to Disrupt Serine Biosynthesis for Cancer Therapy.

Min Huang, Dingding Gao, Guo-qiang Lin, 2023, Journal of medicinal chemistry.

Discovery of a class of diheteroaromatic amines as orally bioavailable CDK1/4/6 inhibitors.

Min Huang, Yi Chen, Jian Ding, 2017, Bioorganic & medicinal chemistry letters.

Development of the First Generation of Disulfide-Based Subtype-Selective and Potent Covalent Pyruvate Dehydrogenase Kinase 1 (PDK1) Inhibitors.

Min Huang, C. Luo, M. Geng, 2017, Journal of medicinal chemistry.

Discovery and structure-activity-relationship study of novel imidazole cyclopropyl amine analogues for mutant isocitric dehydrogenase 1 (IDH1) inhibitors.

Min Huang, Jian Ding, M. Geng, 2018, Bioorganic & Medicinal Chemistry Letters.

Discovery and structure-activity-relationship study of novel conformationally restricted indane analogues for mutant isocitric dehydrogenase 1 (IDH1) inhibitors.

Min Huang, Jian Ding, M. Geng, 2017, Bioorganic & medicinal chemistry letters.

SLC1A1-mediated cellular and mitochondrial influx of R-2-hydroxyglutarate in vascular endothelial cells promotes tumor angiogenesis in IDH1-mutant solid tumors

Leping Li, Min Huang, Lin-jiang Tong, 2022, Cell Research.

Discovery of PHGDH inhibitors by virtual screening and preliminary structure-activity relationship study.

Min Huang, Dingding Gao, G. Lin, 2022, Bioorganic chemistry.

Identification of metabolic vulnerabilities of receptor tyrosine kinases-driven cancer

Min Huang, Jian Ding, Hanlin Zeng, 2019, Nature Communications.

Discovery of Novel Janus Kinase (JAK) and Histone Deacetylase (HDAC) Dual Inhibitors for the Treatment of Hematological Malignancies.

Min Huang, M. Geng, Hong Liu, 2019, Journal of medicinal chemistry.

Feedback Activation of Leukemia Inhibitory Factor Receptor Limits Response to Histone Deacetylase Inhibitors in Breast Cancer.

Min Huang, Yi Chen, Jian Ding, 2016, Cancer cell.

Hedgehog pathway orchestrates the interplay of histone modifications and tailors combination epigenetic therapies in breast cancer

Min Huang, Hanlin Zeng, Shuai Tang, 2023, Acta pharmaceutica Sinica. B.

6‐Methoxyethylamino‐numonafide inhibits hepatocellular carcinoma xenograft growth as a single agent and in combination with sorafenib

Min Huang, A. Mazar, Yanning Liu, 2017, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Identification of epipolythiodioxopiperazines HDN-1 and chaetocin as novel inhibitor of heat shock protein 90

Ming Liu, T. Zhu, Q. Gu, 2015, Oncotarget.

Discovery of Novel Imidazo[4,5-c]quinoline Derivatives to Treat Inflammatory Bowel Disease (IBD) by Inhibiting Multiple Proinflammatory Signaling Pathways and Restoring Intestinal Homeostasis.

Yu Zhou, Min Huang, M. Geng, 2022, Journal of medicinal chemistry.

JX06 Selectively Inhibits Pyruvate Dehydrogenase Kinase PDK1 by a Covalent Cysteine Modification.

Hualiang Jiang, Zhixiang Wu, Min Huang, 2015, Cancer research.

Identification of metabolic vulnerabilities of receptor tyrosine kinases-driven cancer

Min Huang, Jian Ding, Hanlin Zeng, 2019, Nature Communications.

Pentasaccharide resin glycosides with multidrug resistance reversal activities from the seeds of Pharbitis nil

Min Huang, Jun Li, Wen-qiong Wang, 2017 .

Discovery of Novel Pyrrolo[2,3-d]pyrimidine-based Derivatives as Potent JAK/HDAC Dual Inhibitors for the Treatment of Refractory Solid Tumors.

Yu Zhou, Min Huang, M. Geng, 2021, Journal of medicinal chemistry.

α2,6-hyposialylation of c-Met abolishes cell motility of ST6Gal-I-knockdown HCT116 cells

Jian Ding, M. Geng, J. Qian, 2009, Acta Pharmacologica Sinica.

Cyanobacterial peptides as a prototype for the design of cathepsin D inhibitors

Wei Zhang, Keting Bao, Shuai Tang, 2017, Journal of peptide science : an official publication of the European Peptide Society.

Identification of Epigallocatechin-3- Gallate as an Inhibitor of Phosphoglycerate Mutase 1

Min Huang, Jian Ding, M. Geng, 2017, Front. Pharmacol..

Phosphoglycerate mutase 1 promotes cancer cell migration independent of its metabolic activity

Min Huang, Jian Ding, M. Geng, 2017, Oncogene.

Discovery and structure activity relationship study of novel indazole amide inhibitors for extracellular signal-regulated kinase1/2 (ERK1/2).

Min Huang, Jian Ding, M. Geng, 2016, Bioorganic & medicinal chemistry letters.

Tetrahydroisoquinolines as novel histone deacetylase inhibitors for treatment of cancer

M. Geng, B. Xiong, Hongchun Liu, 2016, Acta pharmaceutica Sinica. B.

Tetrandrine synergizes with MAPK inhibitors in treating KRAS-mutant pancreatic ductal adenocarcinoma via collaboratively modulating the TRAIL-death receptor axis.

Min Huang, Shuai Tang, T. Yuan, 2023, Pharmacological research.

Identification of benzo[b]thiophene-1,1-dioxide derivatives as novel PHGDH covalent inhibitors.

Dingding Gao, Shuai Tang, Xinglu Cao, 2024, Bioorganic chemistry.

Low‐Dose Chemotherapy Preferentially Shapes the Ileal Microbiome and Augments the Response to Immune Checkpoint Blockade by Activating AIM2 Inflammasome in Ileal Epithelial Cells

Shuai Tang, Congying Pu, Jun Xu, 2024, Advanced science.