Erik Pong

发表

Potent in vitro and in vivo activity of an Fc-engineered humanized anti-HM1.24 antibody against multiple myeloma via augmented effector function.

G. A. Lazar, K. Anderson, N. Munshi, 2012, Blood.

hematologic malignancies and exhibits potent in vitro and in vivo antitumor activity against Fc-engineered anti-CD40 antibody enhances multiple effector functions

J. Desjarlais, E. Zhukovsky, H. Horton, 2012 .

Fc-engineered anti-CD40 antibody enhances multiple effector functions and exhibits potent in vitro and in vivo antitumor activity against hematologic malignancies.

J. Desjarlais, E. Zhukovsky, H. Horton, 2010, Blood.

A robust heterodimeric Fc platform engineered for efficient development of bispecific antibodies of multiple formats.

J. Desjarlais, Alex Nisthal, R. Rashid, 2019, Methods.

Suppression of Rheumatoid Arthritis B Cells by XmAb5871, an Anti‐CD19 Antibody That Coengages B Cell Antigen Receptor Complex and Fcγ Receptor IIb Inhibitory Receptor

J. Desjarlais, D. Szymkowski, I. Leung, 2013, Arthritis & rheumatology.

Promoter methylation inhibits APC gene expression by causing changes in chromatin conformation and interfering with the binding of transcription factor CCAAT-binding factor.

G. Deng, M. Sleisenger, Y. S. Kim, 2004, Cancer research.

Suppresses Humoral Immunity in Systemic RIIb and B Cell Receptor Complex g Antibody-Mediated Coengagement of Fc

J. Desjarlais, D. Szymkowski, J. Zalevsky, 2011 .

Accelerated Clearance and Degradation of Cell-Free HIV by Neutralizing Antibodies Occurs via FcγRIIb on Liver Sinusoidal Endothelial Cells by Endocytosis

Murugesan V. S. Rajaram, D. Burton, Jonghan Kim, 2021, The Journal of Immunology.

Reduction of total IgE by targeted coengagement of IgE B-cell receptor and FcγRIIb with Fc-engineered antibody.

J. Desjarlais, D. Szymkowski, H. Horton, 2012, The Journal of allergy and clinical immunology.

Immunotherapy with Long-Lived Anti-CD123 × Anti-CD3 Bispecific Antibodies Stimulates Potent T Cell-Mediated Killing of Human AML Cell Lines and of CD123+ Cells in Monkeys: A Potential Therapy for Acute Myelogenous Leukemia

J. Desjarlais, D. Szymkowski, R. Rashid, 2014 .

Antibody-Mediated Coengagement of FcγRIIb and B Cell Receptor Complex Suppresses Humoral Immunity in Systemic Lupus Erythematosus

J. Desjarlais, D. Szymkowski, J. Zalevsky, 2011, The Journal of Immunology.

Methylation in hMLH1 promoter interferes with its binding to transcription factor CBF and inhibits gene expression

G. Deng, Erik Pong, Ada Chen, 2001, Oncogene.

Potent in vitro and in vivo activity of an Fc-engineered anti-CD19 monoclonal antibody against lymphoma and leukemia.

Holly M Horton, Eugene A Zhukovsky, John R Desjarlais, 2008, Cancer research.

CCAAT-Binding Factor Interfering with the Binding of Transcription Factor Causing Changes in Chromatin Conformation and Gene Expression by APC Promoter Methylation Inhibits

G. Deng, M. Sleisenger, G. Song, 2004 .

A novel bispecific antibody format enables simultaneous bivalent and monovalent co-engagement of distinct target antigens

G. A. Lazar, G. Lazar, S. Karki, 2011, mAbs.

Engineering fully human monoclonal antibodies from murine variable regions.

John R Desjarlais, Greg A Lazar, J. Desjarlais, 2010, Journal of molecular biology.

Inhibition of B cell receptor-mediated activation of primary human B cells by coengagement of CD19 and FcgammaRIIb with Fc-engineered antibodies.

G. A. Lazar, John R Desjarlais, Igor Vostiar, 2008, Molecular immunology.

Tuning T Cell Affinity Improves Efficacy and Safety of Anti-CD38 × Anti-CD3 Bispecific Antibodies in Monkeys - a Potential Therapy for Multiple Myeloma

J. Desjarlais, Suzanne Schubbert, D. Szymkowski, 2015 .

Inhibition of B cell activation following in vivo co-engagement of B cell antigen receptor and Fcγ receptor IIb in non-autoimmune-prone and SLE-prone mice

C. Putterman, C. Jacob, D. Szymkowski, 2020, Journal of translational autoimmunity.

Immunotherapy with Long-Lived Anti-CD38 × Anti-CD3 Bispecific Antibodies Stimulates Potent T Cell-Mediated Killing of Human Myeloma Cell Lines and CD38+ Cells in Monkeys: A Potential Therapy for Multiple Myeloma

J. Desjarlais, D. Szymkowski, R. Rashid, 2014 .

Immune suppression in cynomolgus monkeys by XPro9523

J. Desjarlais, G. Lazar, D. Szymkowski, 2013, mAbs.