T. Tolbert

发表

High-throughput biophysical analysis and data visualization of conformational stability of an IgG1 monoclonal antibody after deglycosylation.

C Russell Middaugh, David D Weis, Sangeeta B Joshi, 2013, Journal of pharmaceutical sciences.

3D C(CC)H TOCSY experiment for assigning protons and carbons in uniformly 13C- and selectively 2H-labeled RNA.

J. Williamson, T. Tolbert, K. Dayie, 1998, Journal of magnetic resonance.

Impact of Glycosylation on the Local Backbone Flexibility of Well-Defined IgG1-Fc Glycoforms Using Hydrogen Exchange-Mass Spectrometry.

S. Joshi, D. Volkin, D. Weis, 2018, Journal of pharmaceutical sciences.

A Multidimensional Analytical Comparison of Remicade and the Biosimilar Remsima.

B. Ruotolo, M. Urh, S. Schwendeman, 2017, Analytical chemistry.

Versatile on-resin synthesis of high mannose glycosylated asparagine with functional handles.

R. Chen, T. Tolbert, Mark A. Pawlicki, 2014, Carbohydrate research.

Study of on-resin convergent synthesis of N-linked glycopeptides containing a large high mannose N-linked oligosaccharide.

R. Chen, T. Tolbert, 2010, Journal of the American Chemical Society.

Preparation of Specifically Deuterated and 13C-Labeled RNA for NMR Studies Using Enzymatic Synthesis†

J. Williamson, T. Tolbert, 1997 .

Targeting a homogeneously glycosylated antibody Fc to bind cancer cells using a synthetic receptor ligand.

Rui-Hong Chen, T. Tolbert, Junpeng Xiao, 2009, Journal of the American Chemical Society.

Conjugation of glycopeptide thioesters to expressed protein fragments: semisynthesis of glycosylated interleukin-2.

Chi‐Huey Wong, T. Tolbert, 2004, Methods in molecular biology.

A new strategy for glycoprotein synthesis: ligation of synthetic glycopeptides with truncated proteins expressed in E. coli as TEV protease cleavable fusion protein.

Chi‐Huey Wong, D. Franke, T. Tolbert, 2005, Bioorganic & medicinal chemistry.

Photoinduced Tyrosine Side Chain Fragmentation in IgG4-Fc: Mechanisms and Solvent Isotope Effects.

Huan Kang, C. Schöneich, T. Tolbert, 2018, Molecular pharmaceutics.

Corrigendum: Human gut Bacteroidetes can utilize yeast mannan through a selfish mechanism

Spencer J. Williams, A. Thompson, H. Gilbert, 2015, Nature.

Design of Small Molecules That Recognize RNA: Development of Aminoglycosides as Potential Antitumor Agents That Target Oncogenic RNA Sequences

Chi‐Huey Wong, S. J. Sucheck, T. Tolbert, 2000 .

Site-specific chemical modification of a glycoprotein fragment expressed in yeast.

T. Tolbert, Junpeng Xiao, 2011, Methods in molecular biology.

Designing inhibitors of dehydroquinate synthase. Structural simplicity versus inhibitory potency

J. W. Frost, L. Piehler, J. Montchamp, 1993 .

Effects of glycan structure on the stability and receptor binding of an IgG4-Fc.

Huan Kang, C. Schöneich, T. Tolbert, 2019, Journal of pharmaceutical sciences.

Comparative Evaluation of the Chemical Stability of 4 Well-Defined Immunoglobulin G1-Fc Glycoforms.

D. Volkin, C. Schöneich, Olivier Mozziconacci, 2016, Journal of pharmaceutical sciences.

Subtilisin-catalyzed glycopeptide condensation.

Chi‐Huey Wong, T. Tolbert, 2004, Methods in molecular biology.

Human gut Bacteroidetes can utilize yeast mannan through a selfish mechanism

Eric C. Martens, Harry J. Gilbert, Andrew J. Thompson, 2015, Nature.

Enzyme-Catalyzed Synthesis of a Hybrid N-Linked Oligosaccharide using N-Acetylglucosaminyltransferase I

R. Chen, B. S. Hamilton, T. Tolbert, 2008 .

Carbohydrates | Carbohydrate Chains: Enzymatic and Chemical Synthesis

Chi‐Huey Wong, T. Tolbert, 2021, Encyclopedia of Biological Chemistry III.

On-resin convergent synthesis of a glycopeptide from HIV gp120 containing a high mannose type N-linked oligosaccharide.

R. Chen, T. Tolbert, 2011, Methods in molecular biology.

Carbohydrate Chains: Enzymatic and Chemical Synthesis

Chi‐Huey Wong, T. Tolbert, 2005 .

Synthesis of polymerizable protein monomers for protein-acrylamide hydrogel formation.

T. Tolbert, Junpeng Xiao, 2009, Biomacromolecules.

Preparation of Specifically Deuterated RNA for NMR Studies Using a Combination of Chemical and Enzymatic Synthesis

J. Williamson, T. Tolbert, 1996 .

Preparation of specifically 2H- and 13C-labeled ribonucleotides.

L. Scott, J. Williamson, T. Tolbert, 2000, Methods in enzymology.

Synthesis of RNA with selective isotopic labels for NMR structural studies

T. Tolbert, 1998 .

Synthesis of a Bifunctional Peptide Inhibitor-IgG1 Fc Fusion That Suppresses Experimental Autoimmune Encephalomyelitis.

T. Siahaan, T. Tolbert, P. Kiptoo, 2017, Bioconjugate chemistry.

Structural characterization of the Man5 glycoform of human IgG3 Fc

Ishan S. Shah, K. Battaile, S. Lovell, 2017, Molecular immunology.

Production, Characterization, and Biological Evaluation of Well-Defined IgG1 Fc Glycoforms as a Model System for Biosimilarity Analysis.

Ishan S. Shah, S. Joshi, D. Volkin, 2016, Journal of pharmaceutical sciences.

New methods for proteomic research: preparation of proteins with N-terminal cysteines for labeling and conjugation.

Chi‐Huey Wong, T. Tolbert, 2002, Angewandte Chemie.

Disulfide Bond Characterization of Endogenous IgG3 Monoclonal Antibodies Using LC-MS: An Investigation of IgG3 Disulfide-mediated Isoforms.

Ishan S. Shah, J. Lakbub, Zhikai Zhu, 2016, Analytical methods : advancing methods and applications.

Multifaceted assessment of rituximab biosimilarity: The impact of glycan microheterogeneity on Fc function.

B. Ruotolo, D. Weis, S. Schwendeman, 2019, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Expression and characterization of human glycosylated interleukin-1 receptor antagonist in Pichia pastoris.

B. S. Hamilton, T. Tolbert, Y. Brede, 2008, Protein expression and purification.

Correlating the Impact of Well-Defined Oligosaccharide Structures on Physical Stability Profiles of IgG1-Fc Glycoforms.

S. Joshi, D. Volkin, J. H. Kim, 2016, Journal of pharmaceutical sciences.

Physical stability comparisons of IgG1-Fc variants: effects of N-glycosylation site occupancy and Asp/Gln residues at site Asn 297.

S. Joshi, D. Volkin, J. H. Kim, 2014, Journal of pharmaceutical sciences.

Synthesis of N-terminally linked protein dimers and trimers by a combined native chemical ligation-CuAAC click chemistry strategy.

Thomas J Tolbert, Junpeng Xiao, T. Tolbert, 2009, Organic letters.

Conjugation site heterogeneity causes variable electrostatic properties in Fc conjugates.

J. Laurence, W. Zhou, Nicholas J. Boylan, 2013, Bioconjugate chemistry.

Biosimilarity under stress: A forced degradation study of Remicade® and Remsima™

B. Ruotolo, S. Schwendeman, S. Saveliev, 2017, mAbs.

Increasing solubility of proteins and peptides by site-specific modification with betaine.

T. Tolbert, Junpeng Xiao, A. Burn, 2008, Bioconjugate chemistry.

Modular assembly of dimeric HIV fusion inhibitor peptides with enhanced antiviral potency.

T. Tolbert, Junpeng Xiao, 2013, Bioorganic & medicinal chemistry letters.

New Methods for Proteomic Research: Preparation of Proteins with N-Terminal Cysteines for Labeling and Conjugation This research was supported by the NIH (R37 GM44154).

Chi-Huey Wong, Chi‐Huey Wong, T. Tolbert, 2002 .

Conjugation site heterogeneity causes variable electrostatic properties in Fc conjugates.

J. Laurence, W. Zhou, Nicholas J. Boylan, 2013, Bioconjugate chemistry.

Synthesis of N-terminally linked protein and peptide dimers by native chemical ligation.

B. S. Hamilton, T. Tolbert, Junpeng Xiao, 2010, Bioconjugate chemistry.

Disulfide Bond Characterization of Endogenous IgG3 Monoclonal Antibodies Using LC-MS: An Investigation of IgG3 Disulfide-mediated Isoforms.

Ishan S. Shah, J. Lakbub, Zhikai Zhu, 2016, Analytical methods : advancing methods and applications.