I. Campbell

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Topical application of human-derived Ig isotypes for the control of acute respiratory infection evaluated in a human CD89-expressing mouse model

A. Zuercher, M. Ng, S. Koernig, 2019, Mucosal Immunology.

Treating murine inflammatory diseases with an anti-erythrocyte antibody

A. Zuercher, S. Koernig, F. Käsermann, 2019, Science Translational Medicine.

Differing roles for urokinase and tissue-type plasminogen activator in collagen-induced arthritis.

J. Hamilton, I. Campbell, A. Cook, 2002, The American journal of pathology.

Cytokine modulation of plasminogen activator inhibitor-1 (PAI-1) production by human articular cartilage and chondrocytes. Down-regulation by tumor necrosis factor alpha and up-regulation by transforming growth factor-B basic fibroblast growth factor.

U. Novak, J. Hamilton, J. Wojta, 1994, Biochimica et biophysica acta.

Recombinant human interleukin-1 inhibits plasminogen activator inhibitor-1 (PAI-1) production by human articular cartilage and chondrocytes.

L. Lund, U. Novak, J. Hamilton, 1991, Biochemical and biophysical research communications.

Distinct roles for the NF-kappaB1 (p50) and c-Rel transcription factors in inflammatory arthritis.

I. Wicks, S. Gerondakis, I. Campbell, 2000, The Journal of clinical investigation.

Molecular targets in immune‐mediated diseases: the case of tumour necrosis factor and rheumatoid arthritis

I. Wicks, I. Campbell, L. Roberts, 2003, Immunology and cell biology.

vaccine enhancement The dendritic cell subtype-restricted C-type lectin Clec9A is a target for

M. Wright, A. Lew, J. Lo, 2013 .

The dendritic cell subtype-restricted C-type lectin Clec9A is a target for vaccine enhancement.

M. Wright, Li Wu, A. Lew, 2008, Blood.

Interleukin-6 modulates production of T lymphocyte-derived cytokines in antigen-induced arthritis and drives inflammation-induced osteoclastogenesis.

I. Wicks, A. van Nieuwenhuijze, N. Sims, 2006, Arthritis and rheumatism.

Generation and Novel Distribution of Matrix Metalloproteinase-derived Aggrecan Fragments in Porcine Cartilage Explants*

T. Hardingham, R. Hembry, A. Fosang, 2000, The Journal of Biological Chemistry.

ADAMTS-1-knockout mice do not exhibit abnormalities in aggrecan turnover in vitro or in vivo.

C. Little, M. Pritchard, D. Belluoccio, 2005, Arthritis and rheumatism.

Key Role of Suppressor of Cytokine Signaling 3 in Regulating gp130 Cytokine–Induced Signaling and Limiting Chondrocyte Responses During Murine Inflammatory Arthritis

W. Alexander, I. Wicks, B. Croker, 2014, Arthritis & rheumatology.

The role of the interleukin-6 family of cytokines in inflammatory arthritis and bone turnover.

I. Wicks, M. Ernst, P. Egan, 2003, Arthritis and rheumatism.

Production of macrophage colony-stimulating factor (M-CSF) by human articular cartilage and chondrocytes. Modulation by interleukin-1 and tumor necrosis factor alpha.

J. Hamilton, I. Campbell, G. Ianches, 1993, Biochimica et biophysica acta.

Effects of tumor necrosis factor α and β on resorption of human articular cartilage and production of plasminogen activator by human articular chondrocytes

J. Hamilton, M. J. Roberts, K. Muirden, 1990 .

G-CSF and Neutrophils Are Nonredundant Mediators of Murine Experimental Autoimmune Uveoretinitis.

I. Wicks, P. McMenamin, B. McKenzie, 2016, The American journal of pathology.

Therapeutic Effect of IVIG on Inflammatory Arthritis in Mice Is Dependent on the Fc Portion and Independent of Sialylation or Basophils

A. Zuercher, S. Miescher, F. Käsermann, 2014, The Journal of Immunology.

A key role for G-CSF-induced neutrophil production and trafficking during inflammatory arthritis.

M. Norman, M. Hickey, A. Roberts, 2008, Blood.

Therapeutic Targeting of the G-CSF Receptor Reduces Neutrophil Trafficking and Joint Inflammation in Antibody-Mediated Inflammatory Arthritis

Michael J. Wilson, M. Ng, Adriana Baz Morelli, 2016, The Journal of Immunology.

Protection from collagen-induced arthritis in granulocyte-macrophage colony-stimulating factor-deficient mice.

J. Hamilton, A. Dunn, R. Bischof, 1998, Journal of immunology.

Will sialylation change intravenous immunoglobulin therapy in the future?

F. Käsermann, I. Campbell, 2014, Clinical and experimental immunology.

Acute CD4+ T lymphocyte-dependent interleukin-1-driven arthritis selectively requires interleukin-2 and interleukin-4, joint macrophages, granulocyte-macrophage colony-stimulating factor, interleukin-6, and leukemia inhibitory factor.

I. Wicks, N. Van Rooijen, K. E. Lawlor, 2005, Arthritis and rheumatism.

Topical application of nebulized human IgG, IgA and IgAM in the lungs of rats and non-human primates

A. Zuercher, S. Miescher, D. Metzger, 2019, Respiratory Research.

The mouse mast cell-restricted tetramer-forming tryptases mouse mast cell protease 6 and mouse mast cell protease 7 are critical mediators in inflammatory arthritis.

I. Wicks, David M. Lee, R. Stevens, 2008, Arthritis and rheumatism.

Molecular and cellular mediators of interleukin-1-dependent acute inflammatory arthritis.

Li Wu, I. Wicks, K. E. Lawlor, 2001, Arthritis and rheumatism.

Granulocyte-macrophage colony stimulating factor exacerbates collagen induced arthritis in mice

J. Hamilton, A. Bendele, I. Campbell, 1997, Annals of the rheumatic diseases.

ADAMTS5 is the major aggrecanase in mouse cartilage in vivo and in vitro

A. Fourie, C. Little, A. Fosang, 2005, Nature.

Critical role for granulocyte colony-stimulating factor in inflammatory arthritis.

A. Roberts, I. Wicks, A. van Nieuwenhuijze, 2004, Proceedings of the National Academy of Sciences of the United States of America.

The colony‐stimulating factors and collagen‐induced arthritis: exacerbation of disease by M‐CSF and G‐CSF and requirement for endogenous M‐CSF

J. Hamilton, R. Bischof, I. Campbell, 2000, Journal of leukocyte biology.

Collagen‐induced arthritis in C57BL/6 (H‐2b) mice: new insights into an important disease model of rheumatoid arthritis

I. Wicks, J. Hamilton, I. Campbell, 2000, European journal of immunology.

Human articular cartilage and chondrocytes produce hemopoietic colony-stimulating factors in culture in response to IL-1.

U. Novak, J. Hamilton, J. Cebon, 1991, Journal of immunology.

Vascular cell adhesion molecule‐1 (VCAM‐1) blockade in collagen‐induced arthritis reduces joint involvement and alters B cell trafficking

I. Campbell, I. Wicks, R. Carter, 2002, Clinical and experimental immunology.

Stimulation of human chondrocyte prostaglandin E2 production by recombinant human interleukin-1 and tumour necrosis factor.

J. Hamilton, I. Campbell, D. S. Piccoli, 1990, Biochimica et biophysica acta.

Characterization of latent and active forms of cartilage proteinases produced by normal immature rabbit articular cartilage in tissue culture.

M. Britz, J. Sandy, I. Campbell, 1983, Arthritis and rheumatism.

Factor-Deficient Mice Colony-Stimulating Granulocyte-Macrophage Protection from Collagen-Induced Arthritis in

J. Hamilton, R. Dunn, R. Bischof, 2013 .

Blockade of collagen-induced arthritis post-onset by antibody to granulocyte-macrophage colony-stimulating factor (GM-CSF): requirement for GM-CSF in the effector phase of disease

J. Hamilton, I. Campbell, A. Cook, 2001, Arthritis research.

Recombinant human interleukin-1 stimulates human articular cartilage to undergo resorption and human chondrocytes to produce both tissue- and urokinase-type plasminogen activator.

J. Hamilton, D. Butler, I. Campbell, 1988, Biochimica et biophysica acta.

Regulation of plasminogen activator activity in arthritic joints.

P. Hart, J. Hamilton, I. Campbell, 1991, The Journal of rheumatology. Supplement.

The action of human articular-cartilage metalloproteinase on proteoglycan and link protein. Similarities between products of degradation in situ and in vitro.

P. Roughley, J. Mort, I. Campbell, 1986, The Biochemical journal.

Defective Gp130-Mediated Signal Transducer and Activator of Transcription (Stat) Signaling Results in Degenerative Joint Disease, Gastrointestinal Ulceration, and Failure of Uterine Implantation

W. Alexander, I. Wicks, D. Tarlinton, 2001, The Journal of experimental medicine.

G-CSF and GM-CSF as therapeutic targets in rheumatoid arthritis

I. Wicks, B. McKenzie, I. Campbell, 2009, Nature Reviews Rheumatology.

Differentiation of Inflammatory Dendritic Cells Is Mediated by NF-κB1–Dependent GM-CSF Production in CD4 T Cells

I. Wicks, S. Gerondakis, A. van Nieuwenhuijze, 2011, The Journal of Immunology.

Autoimmune regulator controls T cell help for pathogenetic autoantibody production in collagen-induced arthritis.

I. Wicks, H. Scott, D. Tarlinton, 2009, Arthritis and rheumatism.

Endogenous IL-11 is pro-inflammatory in acute methylated bovine serum albumin/interleukin-1-induced (mBSA/IL-1)arthritis.

I. Wicks, L. Robb, I. Campbell, 2005, Cytokine.

Severe inflammatory arthritis and lymphadenopathy in the absence of TNF.

I. Wicks, I. Campbell, K. O’Donnell, 2001, The Journal of clinical investigation.

rIgG1 Fc Hexamer Inhibits Antibody-Mediated Autoimmune Disease via Effects on Complement and FcγRs

A. Zuercher, S. Koernig, Adriana Baz Morelli, 2018, The Journal of Immunology.

Human articular cartilage secretes characteristic metal dependent proteinases upon stimulation by mononuclear cell factor.

P. Roughley, J. Mort, I. Campbell, 1986, The Journal of rheumatology.

GM-CSF Production in CD4 T CellsDependent - B1 k Cells Is Mediated by NF-Differentiation of Inflammatory Dendritic

I. Wicks, S. Gerondakis, J. Villadangos, 2011 .

Production of leukemia inhibitory factor by human articular chondrocytes and cartilage in response to interleukin-1 and tumor necrosis factor alpha.

U. Novak, J. Hamilton, P. Waring, 1993, Arthritis and rheumatism.

Plasminogen Activators and Their Inhibitors in Arthritic Disease

J. Hamilton, J. Wojta, I. Campbell, 1992, Annals of the New York Academy of Sciences.

Bcl‐2 overexpression ameliorates immune complex‐mediated arthritis by altering FcγRIIb expression and monocyte homeostasis

A. Strasser, I. Wicks, J. Vince, 2013, Journal of leukocyte biology.

Topical application of human-derived Ig isotypes for the control of acute respiratory infection evaluated in a human CD89-expressing mouse model

A. Zuercher, M. Ng, S. Koernig, 2019, Mucosal Immunology.

Development of spontaneous multisystem autoimmune disease and hypersensitivity to antibody-induced inflammation in Fcgamma receptor IIa-transgenic mice.

I. Wicks, P. Hogarth, R. Slocombe, 2005, Arthritis and rheumatism.

Modulation of Neutrophil Function by Recombinant Human IgG1 Fc Hexamer in the Endogenous K/BxN Mouse Model of Rheumatoid Arthritis

F. Käsermann, H. Whetstone, B. Lewis, 2023, Pharmacology.

Immunodetection and characterization of the degradation of cartilage proteoglycans in vitro and in vivo.

P. Roughley, A. Poole, I. Campbell, 1987, Journal of Rheumatology.

Promotion of the local differentiation of murine Th17 cells by synovial macrophages during acute inflammatory arthritis.

I. Wicks, A. van Nieuwenhuijze, P. Egan, 2008, Arthritis and rheumatism.

Effects of tumor necrosis factor alpha and beta on resorption of human articular cartilage and production of plasminogen activator by human articular chondrocytes.

J. Hamilton, M. J. Roberts, K. Muirden, 1990, Arthritis & Rheumatism.

Portion and Independent of Sialylation or Arthritis in Mice Is Dependent on the Fc Therapeutic Effect of IVIG on Inflammatory

A. Zuercher, S. Miescher, F. Käsermann, 2014 .

Exacerbation of acute inflammatory arthritis by the colony‐stimulating factors CSF‐1 and granulocyte macrophage (GM)‐CSF: evidence of macrophage infiltration and local proliferation

J. Hamilton, R. Bischof, Hamilton, 2000, Clinical and experimental immunology.

Recombinant human interleukin-1 inhibits plasminogen activator inhibitor-1 (PAI-1) production by human articular cartilage and chondrocytes.

L. Lund, U. Novak, J. Hamilton, 1991, Biochemical and biophysical research communications.

Mononuclear cell factor modulates the concomitant release of proteoglycan and latent proteinase by human articular cartilage in organ culture.

P. Roughley, J. Mort, I. Campbell, 1986, Agents and actions. Supplements.