J. Steven

发表

Improving the pharmacokinetic properties of biologics by fusion to an anti-HSA shark VNAR domain

Y. Vugmeyster, T. Hickling, C. Barelle, 2012, mAbs.

Modeling acute lesion volume and topography for genetic analysis ( MRI-GENIE study )

M. Fornage, J. Broderick, O. Wu, 2022 .

An Anti-hTNF-α Variable New Antigen Receptor Format Demonstrates Superior in vivo Preclinical Efficacy to Humira® in a Transgenic Mouse Autoimmune Polyarthritis Disease Model

Obinna C Ubah, C. Barelle, A. Porter, 2019, Front. Immunol..

Novel, Anti-hTNF-α Variable New Antigen Receptor Formats with Enhanced Neutralizing Potency and Multifunctionality, Generated for Therapeutic Development

Obinna C Ubah, C. Barelle, J. Steven, 2017, Front. Immunol..

Anti-DLL4 VNAR targeted nanoparticles for targeting of both tumour and tumour associated vasculature.

C. Barelle, C. Scott, M. Greene, 2020, Nanoscale.

Microenvironment Function Due to Disturbance of Subretinal Loss of Caveolin-1 Impairs Retinal Neurobiology :

Fain, D. Birch, M. Woodruff, 2012 .

Uveitis Therapy With Shark Variable Novel Antigen Receptor Domains Targeting Tumor Necrosis Factor Alpha or Inducible T-Cell Costimulatory Ligand

Obinna C Ubah, Kathryn L. Pepple, R. V. Van Gelder, 2019, Translational vision science & technology.

Anti-ICOSL New Antigen Receptor Domains Inhibit T Cell Proliferation and Reduce the Development of Inflammation in the Collagen-Induced Mouse Model of Rheumatoid Arthritis

D. Luxenberg, M. Whitters, C. Barelle, 2018, Journal of immunology research.

Relative Biological Effectiveness of 12 C and 28 Si radiation in C 57 BL / 6 J mice

A. Fornace, S. Suman, K. Datta, 2014 .

In Vitro Maturation of a Humanized Shark VNAR Domain to Improve Its Biophysical Properties.

Obinna C Ubah, Magdalena J Buschhaus, C. Barelle, 2020, Methods in molecular biology.

A humanised murine monoclonal antibody with broad serogroup specificity protects mice from challenge with Venezuelan equine encephalitis virus.

C. Logue, S. Perkins, L. O’Brien, 2011, Antiviral research.

CDR-restricted engineering of native human scFvs creates highly stable and soluble bifunctional antibodies for subcutaneous delivery

Jason M. Edmonds, W. Somers, Janet E. Paulsen, 2013, mAbs.

likelihood for a history of acute myocardial infarction by race and ethnicity: Results from the Third National Health and Nutrition Examination Survey

E. Ford, K. Greenlund, J. Croft, 2000 .

Oriented attachment of VNAR proteins, via site-selective modification, on PLGA–PEG nanoparticles enhances nanoconjugate performance† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c9cc02655j

Daniel A. Richards, V. Chudasama, C. Barelle, 2019, Chemical communications.

Impact of manipulations of myogenesis in utero on the performance of adult skeletal muscle.

C. Maltin, A. Sneddon, M. Delday, 2001, Reproduction.

University of Groningen β3-Adrenoceptor detection and signal transduction: focus on antibody validation and urinary bladder

M. Dowling, Martina Schmidt, H. Černecká, 2014 .

Shark variable new antigen receptor biologics – a novel technology platform for therapeutic drug development

C. Barelle, A. Porter, J. Steven, 2014, Expert opinion on biological therapy.

Elevated IGF-II mRNA and phosphorylation of 4E-BP1 and p70(S6k) in muscle showing clenbuterol-induced anabolism.

C. Maltin, A. Sneddon, M. Delday, 2001, American journal of physiology. Endocrinology and metabolism.

Therapeutic Potential of Shark Anti-ICOSL VNAR Domains is Exemplified in a Murine Model of Autoimmune Non-Infectious Uveitis

C. Barelle, A. Porter, J. Steven, 2017, Front. Immunol..

Characterization of the immunoglobulin repertoire of the spiny dogfish (Squalus acanthias).

M. Flajnik, H. Shih, Janet E. Paulsen, 2012, Developmental and comparative immunology.

In Vitro Maturation of a Humanized Shark VNAR Domain to Improve Its Biophysical Properties to Facilitate Clinical Development

Obinna C Ubah, C. Barelle, A. Porter, 2017, Front. Immunol..

Next-generation flexible formats of VNAR domains expand the drug platform's utility and developability.

John Steven, Obinna C Ubah, Magdalena J Buschhaus, 2018, Biochemical Society transactions.