E. Mai

发表

Targeting HER2-positive breast cancer with trastuzumab-DM1, an antibody-cytotoxic drug conjugate.

John M Lambert, Wai Lee T Wong, Guangmin Li, 2008, Cancer research.

Conjugation site modulates the in vivo stability and therapeutic activity of antibody-drug conjugates

M. Sliwkowski, R. Scheller, L. Khawli, 2012, Nature Biotechnology.

Onartuzumab (MetMAb): Using Nonclinical Pharmacokinetic and Concentration–Effect Data to Support Clinical Development

M. Merchant, N. Jumbe, I. Nijem, 2013, Clinical Cancer Research.

Mechanistic pharmacokinetic/pharmacodynamic modeling of in vivo tumor uptake, catabolism, and tumor response of trastuzumab maytansinoid conjugates

H. Erickson, J. Tibbitts, G. L. Lewis Phillips, 2014, Cancer Chemotherapy and Pharmacology.

Inhibition of cMet activation by a one-armed antibody

R. Schwall, D. Yansura, D. Reilly, 2004 .

Clinical Cancer esearch cer Therapy : Preclinical ineered Thio-Trastuzumab-DM 1 Conjugate with an roved Therapeutic Index to Target Human Epidermal R wth Factor Receptor 2 – Positive Breast Cancer

S. Spencer, P. Polakis, K. Parsons, 2010 .

HER2-Targeted Therapy Reduces Incidence and Progression of Midlife Mammary Tumors in Female Murine Mammary Tumor Virus huHER2-Transgenic Mice

H. Koeppen, R. Schwall, W. Wong, 2004, Clinical Cancer Research.

Mechanism-Based Pharmacokinetic/Pharmacodynamic Model for THIOMAB™ Drug Conjugates

K. Gadkar, S. Ramanujan, S. Sukumaran, 2014, Pharmaceutical Research.

Function of CSF1 and IL34 in Macrophage Homeostasis, Inflammation, and Cancer

D. Danilenko, J. DeVoss, A. Zarrin, 2019, Front. Immunol..

Trastuzumab uptake and its relation to efficacy in an animal model of HER2-positive breast cancer brain metastasis

H. Phillips, S. Kharbanda, Simon-Peter Williams, 2017, Breast Cancer Research and Treatment.

Antibody targeting of E3 ubiquitin ligases for receptor degradation

Dhara N. Amin, D. Seshasayee, B. Biehs, 2022, Nature.

MetMAb, the one-armed 5D5 anti-c-Met antibody, inhibits orthotopic pancreatic tumor growth and improves survival.

I. Kasman, J. Zha, Zemin Zhang, 2007, Cancer research.

A novel method to produce synthetic murine CXCL10 for efficient screening of functional variants.

B. Vollmar, J. Payandeh, M. Albert, 2021, Bioorganic chemistry.

Anti-CD20/CD3 T cell–dependent bispecific antibody for the treatment of B cell malignancies

Diego Ellerman, Peiyin Wang, Yu-Waye Chu, 2015, Science Translational Medicine.

Nucleic acid capture assay, a new method for direct quantitation of nucleic acids.

P. Jhurani, M. Vasser, M. Jakobsen, 2003, Nucleic acids research.