A. Jakobovits

发表

Functional transplant of megabase human immunoglobulin loci recapitulates human antibody response in mice

Larry L. Green, Atsushi Fukushima, K. Zsebo, 1997, Nature Genetics.

Germ-line transmission and expression of a human-derived yeast artificial chromosome

L. Green, C. E. Maynard-Currie, A. Jakobovits, 1993, Nature.

A discrete element 3' of human immunodeficiency virus 1 (HIV-1) and HIV-2 mRNA initiation sites mediates transcriptional activation by an HIV trans activator

D. Capon, A. Jakobovits, D. H. Smith, 1988 .

Two proto-oncogenes implicated in mammary carcinogenesis, int-1 and int-2, are independently regulated during mouse development.

H. Varmus, G. Shackleford, G. Martin, 1986, Proceedings of the National Academy of Sciences of the United States of America.

Anti-PSCA mAbs inhibit tumor growth and metastasis formation and prolong the survival of mice bearing human prostate cancer xenografts

R. Hubert, O. Witte, A. Raitano, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Target Antigens for Prostate Cancer Immunotherapy

O. Witte, R. Reiter, D. Saffran, 2004, Cancer and Metastasis Reviews.

Monoclonal antibodies to six-transmembrane epithelial antigen of the prostate-1 inhibit intercellular communication in vitro and growth of human tumor xenografts in vivo.

S. Kanner, A. Raitano, Z. An, 2007, Cancer research.

Cancer Epithelia Protease Results in Its Secretion by Prostate and Prostate Catalytic Cleavage of the Androgen-regulated TMPRSS 2 Updated Version

R. Hubert, I. Vivanco, A. Raitano, 2001 .

Production of fully human antibodies by transgenic mice.

A. Jakobovits, 1995, Current opinion in biotechnology.

Tools of the Trade YAC Vectors: Humanizing the mouse genome

A. Jakobovits, 1994, Current Biology.

Acquisition of mitogenic responsiveness by nonresponding lymphocytes upon insertion of appropriate membrane components

N. Sharon, A. Jakobovits, I. Zan‐Bar, 1982, The Journal of experimental medicine.

The Expression of Growth Factors and Growth Factor Receptors During Mouse Embryogenesis

A. Jakobovits, 1986 .

The long-awaited magic bullets: therapeutic human monoclonal antibodies from transgenic mice.

A. Jakobovits, 1998, Expert opinion on investigational drugs.

Human B lymphocytes form rosettes after insertion of T lymphocyte membrane constituents

N. Sharon, A. Jakobovits, M. Rosenberg, 1981, European journal of immunology.

Expression of N-myc in teratocarcinoma stem cells and mouse embryos

M. Schwab, J. Bishop, G. Martin, 1985, Nature.

Catalytic cleavage of the androgen-regulated TMPRSS2 protease results in its secretion by prostate and prostate cancer epithelia.

R. Hubert, E. Chen, I. Vivanco, 2001, Cancer research.

STEAP: a prostate-specific cell-surface antigen highly expressed in human prostate tumors.

R. Hubert, I. Vivanco, A. Raitano, 1999, Proceedings of the National Academy of Sciences of the United States of America.

Monoclonal antibody therapy for prostate cancer.

A. Jakobovits, 2008, Handbook of experimental pharmacology.

Recombinant Antibodies for Immunotherapy: Therapeutic Antibodies from XenoMouse Transgenic Mice

A. Jakobovits, 2009 .

From XenoMouse technology to panitumumab, the first fully human antibody product from transgenic mice

R. Amado, L. Roskos, Xiao-Dong Yang, 2007, Nature Biotechnology.

A discrete element 3' of human immunodeficiency virus 1 (HIV-1) and HIV-2 mRNA initiation sites mediates transcriptional activation by an HIV trans activator

D. Capon, A. Jakobovits, D. H. Smith, 1988, Molecular and cellular biology.

A monoclonal antibody to the human epidermal growth factor receptor

P. Goodfellow, M. Waterfield, B. Ozanne, 1982, Journal of cellular biochemistry.

Eradication of established tumors by a fully human monoclonal antibody to the epidermal growth factor receptor without concomitant chemotherapy.

C. Davis, X. Jia, J. Corvalan, 1999, Cancer research.

Production of transgenic mice with yeast artificial chromosomes.

B. Lamb, K. Peterson, A. Jakobovits, 1997, Methods in molecular biology.

Antigen–specific human monoclonal antibodies from mice engineered with human Ig heavy and light chain YACs

H. Abderrahim, D. Capon, R. McGuinness, 1994, Nature Genetics.

Inactivation of the mouse HPRT locus by a 203-bp retroposon insertion and a 55-kb gene-targeted deletion: establishment of new HPRT-deficient mouse embryonic stem cell lines.

L. Reid, K. Edamura, T. Yoshida, 1997, Genomics.

Inserted H–2 gene membrane products mediate immune response phenotype of antigen-presenting cell

I. Cohen, N. Sharon, A. Jakobovits, 1981, Nature.

Transfer of Membrane Constituents between Cells

N. Sharon, A. Jakobovits, 1982 .

Use of AGS-16M8F as a novel antibody drug conjugate (ADC) for treating renal cancers.

S. Kanner, Z. An, M. Vincent, 2010 .

The human immunoglobulin loci introduced into mice: V (D) and J gene segment usage similar to that of adult humans

M. Gallo, A. Jakobovits, V. Ivanov, 2000, European Journal of Immunology.

Analysis of homozygous mutant chimeric mice: deletion of the immunoglobulin heavy-chain joining region blocks B-cell development and antibody production.

G. Otten, R. McGuinness, J. F. Hales, 1993, Proceedings of the National Academy of Sciences of the United States of America.

Trans‐activation of HIV‐1 LTR‐directed gene expression by tat requires protein kinase C.

D. Capon, A. Rosenthal, A. Jakobovits, 1990, The EMBO journal.

Plucking of lectin receptors from erythrocytes: isolation of cell surface components without the use of detergents.

N. Sharon, A. Jakobovits, Y. Eshdat, 1981, Biochemical and biophysical research communications.

Abstract 4393: ASG-5ME is a novel antibody drug conjugate (ADC) for treating prostate cancers

A. Raitano, Z. An, Leia M. Smith, 2010 .

YAC vectors. Humanizing the mouse genome.

A. Jakobovits, 1994, Current biology : CB.