Y. Akamatsu

发表

Epitope and Fc-Mediated Cross-linking, but Not High Affinity, Are Critical for Antitumor Activity of CD137 Agonist Antibody with Reduced Liver Toxicity

A. Thakur, D. Chao, E. DiGiammarino, 2020, Molecular Cancer Therapeutics.

Whole IgG surface display on mammalian cells: Application to isolation of neutralizing chicken monoclonal anti-IL-12 antibodies.

N. Tsurushita, Zhenghai Xu, Y. Akamatsu, 2007, Journal of immunological methods.

A single-chain immunotoxin against carcinoembryonic antigen that suppresses growth of colorectal carcinoma cells.

J. C. Murphy, K. F. Nolan, R. Kreitman, 1998, Clinical cancer research : an official journal of the American Association for Cancer Research.

Functional Dissection of the α and β Subunits of Transcription Factor PEBP2 and the Redox Susceptibility of Its DNA Binding Activity*

Yoshiaki Ito, K. Shigesada, H. Kagoshima, 1996, The Journal of Biological Chemistry.

Design, creation and in vitro testing of a reduced immunogenicity humanized anti-CD25 monoclonal antibody that retains functional activity.

F. Harding, A. Reddy, P. Hinton, 2019, Protein engineering, design & selection : PEDS.

CTLA4-Ig–Based Bifunctional Costimulation Inhibitor Blocks CD28 and ICOS Signaling to Prevent T Cell Priming and Effector Function

Xiaoqing Lu, J. Samayoa, R. Goenka, 2021, The Journal of Immunology.

Increased frequency of aberrant V(D)J recombination products in core RAG-expressing mice.

F. Alt, D. Dudley, Y. Takahama, 2004, Nucleic acids research.

Synthesis and structural characterization of triple-helical peptides which mimic the ligand binding site of the human macrophage scavenger receptor

K. Yamauchi, H. Hojo, Y. Akamatsu, 1997 .

A Bispecific Molecule Targeting CD40 and Tumor Antigen Mesothelin Enhances Tumor-Specific Immunity

D. Song, A. Wahl, D. Chao, 2019, Cancer Immunology Research.

Bypassing immunization: optimized design of "designer T cells" against carcinoembryonic antigen (CEA)-expressing tumors, and lack of suppression by soluble CEA.

C. Yun, J. C. Murphy, E. Beecham, 1999, Clinical cancer research : an official journal of the American Association for Cancer Research.

Deep mutational scanning of an antibody against epidermal growth factor receptor using mammalian cell display and massively parallel pyrosequencing

R. Dubridge, Verónica Juan, Minhtam Doan, 2013, mAbs.

Distinct Roles of RAG1 and RAG2 in Binding the V(D)J Recombination Signal Sequences

Marjorie A. Oettinger, M. Oettinger, Y. Akamatsu, 1998, Molecular and Cellular Biology.

Redox Regulation of the DNA Binding Activity in Transcription Factor PEBP2

J. Yodoi, K. Hirota, K. Shigesada, 1997, The Journal of Biological Chemistry.

Effect of CpG methylation on RAG1/RAG2 reactivity: implications of direct and indirect mechanisms for controlling V(D)J cleavage

Y. Takahama, H. Nakase, Y. Akamatsu, 2003, EMBO reports.

An anti-PD-1–GITR-L bispecific agonist induces GITR clustering-mediated T cell activation for cancer immunotherapy

W. Liu, Z. Dezső, L. Bigelow, 2022, Nature Cancer.

Deletion of the RAG2 C terminus leads to impaired lymphoid development in mice

Sheryl K Elkin, F. Alt, D. Dudley, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Murinization and H Chain Isotype Matching of the Anti-GITR Antibody DTA-1 Reduces Immunogenicity-Mediated Anaphylaxis in C57BL/6 Mice

D. Hollenbaugh, F. Harding, J. Samayoa, 2017, The Journal of Immunology.

Synthesis and structural characterization of the ligand binding site of macrophage scavenger receptor

H. Hojo, Y. Akamatsu, Yu Nakamura, 2002 .