A. Smolenski

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Glycoprotein Ibα and FcγRIIa play key roles in platelet activation by the colonizing bacterium, Streptococcus oralis

S. Watson, D. Cox, C. Douglas, 2013, Journal of thrombosis and haemostasis : JTH.

Regulation of Human Endothelial Cell Focal Adhesion Sites and Migration by cGMP-dependent Protein Kinase I*

U. Walter, S. Lohmann, W. Poller, 2000, The Journal of Biological Chemistry.

Phosphodiesterases link the aryl hydrocarbon receptor complex to cyclic nucleotide signaling.

A. Smolenski, Simone Kobe de Oliveira, 2009, Biochemical pharmacology.

Lighting up kinase action in platelets

A. Smolenski, 2017, Journal of thrombosis and haemostasis : JTH.

1 Lighting up kinase action in platelets

A. Smolenski, 2017 .

Thrombin and Collagen Induce a Feedback Inhibitory Signaling Pathway in Platelets Involving Dissociation of the Catalytic Subunit of Protein Kinase A from an NFκB-IκB Complex*

U. Walter, S. Lohmann, S. Gambaryan, 2010, The Journal of Biological Chemistry.

Effects of the NO/soluble guanylate cyclase/cGMP system on the functions of human platelets.

U. Walter, R. Zahedi, A. Sickmann, 2018, Nitric oxide : biology and chemistry.

Endothelium-dependent and -independent relaxation and VASP serines 157/239 phosphorylation by cyclic nucleotide-elevating vasodilators in rat aorta.

U. Walter, T. Münzel, J. Bauersachs, 2003, Biochemical pharmacology.

Cyclic nucleotide‐dependent inhibitory signaling interweaves with activating pathways to determine platelet responses

Z. Nagy, A. Smolenski, 2018, Research and practice in thrombosis and haemostasis.

Rap1GAP2 is a new GTPase-activating protein of Rap1 expressed in human platelets.

A. Smolenski, J. Schultess, Oliver Danielewski, 2005, Blood.

Vasodilator-Stimulated Phosphoprotein Serine 239 Phosphorylation as a Sensitive Monitor of Defective Nitric Oxide/cGMP Signaling and Endothelial Dysfunction

T. Meinertz, T. Münzel, M. Oelze, 2000, Circulation research.

Analysis and Regulation of Vasodilator-stimulated Phosphoprotein Serine 239 Phosphorylation in Vitro and in Intact Cells Using a Phosphospecific Monoclonal Antibody*

U. Walter, T. Jarchau, A. Smolenski, 1998, The Journal of Biological Chemistry.

Phosphodiesterase 2A Forms a Complex with the Co-chaperone XAP2 and Regulates Nuclear Translocation of the Aryl Hydrocarbon Receptor*

S. Gambaryan, W. Müller-Esterl, J. A. Guimarães, 2007, Journal of Biological Chemistry.

Overexpression of protein kinase G using adenovirus inhibits cyclin E transcription and mesangial cell cycle.

S. Lohmann, F. Marumo, Y. Terada, 2001, American journal of physiology. Renal physiology.

cGMP-dependent Protein Kinase Type II Regulates Basal Level of Aldosterone Production by Zona Glomerulosa Cells without Increasing Expression of the Steroidogenic Acute Regulatory Protein Gene*

M. Glazova, G. Guillon, S. Gambaryan, 2003, Journal of Biological Chemistry.

Endogenous or overexpressed cGMP-dependent protein kinases inhibit cAMP-dependent renin release from rat isolated perfused kidney, microdissected glomeruli, and isolated juxtaglomerular cells.

U. Walter, S. Lohmann, S. Gambaryan, 1998, Proceedings of the National Academy of Sciences of the United States of America.

cGMP Inhibition of Na+/H+ Antiporter 3 (NHE3) Requires PDZ Domain Adapter NHERF2, a Broad Specificity Protein Kinase G-anchoring Protein*

S. Lohmann, M. Cavet, M. Donowitz, 2005, Journal of Biological Chemistry.

Mechanical stretch up-regulates the B-type natriuretic peptide system in human cardiac fibroblasts: a possible defense against transforming growth factor-β mediated fibrosis

D. Phelan, P. Collier, C. Watson, 2012, Fibrogenesis & tissue repair.

Synaptotagmin-like protein 1 interacts with the GTPase-activating protein Rap1GAP2 and regulates dense granule secretion in platelets.

A. Smolenski, C. Prelle, Jan Babica, 2009, Blood.

Gene Transfer of cGMP-Dependent Protein Kinase I Enhances the Antihypertrophic Effects of Nitric Oxide in Cardiomyocytes

C. Trautwein, H. Drexler, S. Lohmann, 2002, Hypertension.

Synaptotagmin‐like protein 4 and Rab8 interact and increase dense granule release in platelets

A. O’Connor, A. Smolenski, A. Hampson, 2013, Journal of thrombosis and haemostasis : JTH.

KT5823 differentially modulates sodium iodide symporter expression, activity, and glycosylation between thyroid and breast cancer cells.

S. Jhiang, I. Wapnir, Aparna Lakshmanan, 2011, Endocrinology.

Invasive Streptococcus pneumoniae trigger platelet activation via Toll‐like receptor 2

A. Kadioglu, D. Cox, H. Jenkinson, 2010, Journal of thrombosis and haemostasis : JTH.

The NO/cGMP pathway inhibits Rap1 activation in human platelets via cGMP-dependent protein kinase I

A. Smolenski, J. Schultess, Oliver Danielewski, 2005, Thrombosis and Haemostasis.

Phosphorylation of vasodilator-stimulated phosphoprotein: a consequence of nitric oxide- and cGMP-mediated signal transduction in brain capillary endothelial cells and astrocytes.

A. Sporbert, U. Walter, I. Blasig, 1999, Brain research. Molecular brain research.

Functional analysis of cGMP-dependent protein kinases I and II as mediators of NO/cGMP effects

U. Walter, S. Lohmann, S. Gambaryan, 1998, Naunyn-Schmiedeberg's Archives of Pharmacology.

YC-1 potentiates nitric oxide- and carbon monoxide-induced cyclic GMP effects in human platelets.

G. Schultz, U. Walter, A. Friebe, 1998, Molecular pharmacology.

Analysis of Protein Phosphorylation Using Phos‐Tag Gels

Z. Nagy, A. Smolenski, S. Comer, 2018, Current protocols in protein science.

Membrane targeting of cGMP-dependent protein kinase is required for cystic fibrosis transmembrane conductance regulator Cl- channel activation.

A. Houtsmuller, S. Lohmann, E. Ehlert, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Inhibition of calcineurin-NFAT hypertrophy signaling by cGMP-dependent protein kinase type I in cardiac myocytes

H. Drexler, S. Lohmann, B. Pieske, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Changes in milk composition during lactation in the eastern barred bandicoot (Perameles gunnii) (Marsupialia: Peramelidae)

M. Ikonomopoulou, A. Smolenski, R. Rose, 2005 .

Distinct and specific functions of cGMP-dependent protein kinases.

U. Walter, S. Lohmann, A. Vaandrager, 1997, Trends in biochemical sciences.

Analysis of SAGE data in human platelets: Features of the transcriptome in an anucleate cell

T. Dandekar, U. Walter, M. Dittrich, 2006, Thrombosis and Haemostasis.

Regulation of aldosterone production from zona glomerulosa cells by ANG II and cAMP: evidence for PKA-independent activation of CaMK by cAMP.

U. Walter, S. Gambaryan, B. Allolio, 2006, American journal of physiology. Endocrinology and metabolism.

Effects of In Vivo Nitroglycerin Treatment on Activity and Expression of the Guanylyl Cyclase and cGMP-Dependent Protein Kinase and Their Downstream Target Vasodilator-Stimulated Phosphoprotein in Aorta

J. Stasch, U. Walter, T. Meinertz, 2001, Circulation.

WNT‐3a modulates platelet function by regulating small GTPase activity

A. Poole, P. Maguire, A. Smolenski, 2012, FEBS letters.

The Cell Cycle Checkpoint System MAST(L)-ENSA/ARPP19-PP2A is Targeted by cAMP/PKA and cGMP/PKG in Anucleate Human Platelets

U. Walter, R. Zahedi, S. Gambaryan, 2020, Cells.

Inhibition of cGMP-dependent protein kinase II by its own splice isoform.

S. Lohmann, M. Glazova, S. Gambaryan, 2002, Biochemical and biophysical research communications.

cGMP-dependent Protein Kinase Type I Inhibits TAB1-p38 Mitogen-activated Protein Kinase Apoptosis Signaling in Cardiac Myocytes*

Franz Hofmann, Robert Feil, F. Hofmann, 2006, Journal of Biological Chemistry.

Calcium-dependent membrane association sensitizes soluble guanylyl cyclase to nitric oxide

U. Zabel, U. Walter, H. Schmidt, 2002, Nature Cell Biology.

Cyclic GMP-dependent Protein Kinase Signaling Pathway Inhibits RhoA-induced Ca2+ Sensitization of Contraction in Vascular Smooth Muscle*

S. Lohmann, J. Bertoglio, P. Pacaud, 2000, The Journal of Biological Chemistry.

Endothelial Nitric-oxide Synthase (Type III) Is Activated and Becomes Calcium Independent upon Phosphorylation by Cyclic Nucleotide-dependent Protein Kinases*

H. Schmidt, S. Lohmann, A. Sickmann, 2000, The Journal of Biological Chemistry.

Active Rho Kinase (ROK-α) Associates with Insulin Receptor Substrate-1 and Inhibits Insulin Signaling in Vascular Smooth Muscle Cells*

S. Lohmann, O. Sandu, Masa-aki Ito, 2002, The Journal of Biological Chemistry.

Novel roles of cAMP/cGMP‐dependent signaling in platelets

A. Smolenski, A Smolenski, 2012, Journal of thrombosis and haemostasis : JTH.

Cyclic GMP-dependent Protein Kinase Iα Attenuates Necrosis and Apoptosis Following Ischemia/Reoxygenation in Adult Cardiomyocyte*

S. Lohmann, Anindita Das, A. Smolenski, 2006, Journal of Biological Chemistry.

Abstracts from the 8th International Conference on cGMP Generators, Effectors and Therapeutic Implications

Jordi Villà-Freixa, Peter Sandner, Bernd J. Pichler, 2017, BMC Pharmacology and Toxicology.

Quantitative analysis of the cardiac fibroblast transcriptome-implications for NO/cGMP signaling.

U. Walter, S. Lohmann, S. Kneitz, 2004, Genomics.

The RhoA regulators Myo9b and GEF‐H1 are targets of cyclic nucleotide‐dependent kinases in platelets

A. von Kriegsheim, U. Walter, R. Zahedi, 2020, Journal of thrombosis and haemostasis : JTH.

Regulator of G-protein signaling 18 integrates activating and inhibitory signaling in platelets.

G. Elia, A. Smolenski, Kristina Gegenbauer, 2012, Blood.

Cyclic Nucleotide-dependent Protein Kinases Inhibit Binding of 14-3-3 to the GTPase-activating Protein Rap1GAP2 in Platelets*

P. Říha, A. Smolenski, J. Schultess, 2008, Journal of Biological Chemistry.

MKP-1 expression and stabilization and cGK Ialpha prevent diabetes- associated abnormalities in VSMC migration.

S. Lohmann, A. Jacob, N. Begum, 2004, American journal of physiology. Cell physiology.

Insulin inhibits PDGF-directed VSMC migration via NO/ cGMP increase of MKP-1 and its inactivation of MAPKs.

S. Lohmann, J. Molkentin, A. Jacob, 2002, American journal of physiology. Cell physiology.

Cyclic Nucleotide-dependent Protein Kinases Target ARHGAP17 and ARHGEF6 Complexes in Platelets*

A. von Kriegsheim, S. Gambaryan, Z. Nagy, 2015, The Journal of Biological Chemistry.

VASP-dependent regulation of actin cytoskeleton rigidity, cell adhesion, and detachment

W. Baumgartner, A. Simm, M. Reinhard, 2006, Histochemistry and Cell Biology.

Atrial natriuretic peptide-stimulated Ca2+ reabsorption in rabbit kidney requires membrane-targeted, cGMP-dependent protein kinase type II.

S. Lohmann, S. Gambaryan, J. Hoenderop, 1999, Proceedings of the National Academy of Sciences of the United States of America.

cGMP Stimulation of Cystic Fibrosis Transmembrane Conductance Regulator Cl− Channels Co-expressed with cGMP-dependent Protein Kinase Type II but Not Type Iβ*

S. Lohmann, T. Jarchau, B. Scholte, 1997, The Journal of Biological Chemistry.

Cyclic GMP Dependent Protein Kinase (cGK, PKG)

S. Lohmann, A. Smolenski, 2002 .

Cyclic Nucleotide Dependent Dephosphorylation of Regulator of G-Protein Signaling 18 in Human Platelets

Z. Nagy, A. Smolenski, Kristina Gegenbauer, 2013, PloS one.

131001 pS RGS18 clean-revised

Z. Nagy, A. Smolenski, Kristina Gegenbauer, 2014 .

Title Regulator of G-protein signaling protein 18 integratesactivating and inhibitory signaling in platelets

G. Elia, A. Smolenski, Kristina Gegenbauer, 2017 .

signaling in platelets Regulator of G-protein signaling 18 integrates activating and inhibitory

G. Elia, A. Smolenski, Kristina Gegenbauer, 2012 .

Abstracts from the 8th International Conference on cGMP Generators, Effectors and Therapeutic Implications

James C. Campbell, Dong I. Lee, M. Zaccolo, 2017, BMC Pharmacology and Toxicology.

Novel roles of cAMP/cGMP‐dependent signaling in platelets

A. Smolenski, 2012, Journal of thrombosis and haemostasis : JTH.

The NO/cGMP pathway inhibits Rap1 activation in human platelets via cGMP-dependent protein kinase I

A. Smolenski, J. Schultess, Oliver Danielewski, 2005, Thrombosis and Haemostasis.

Analysis of protein phosphorylation using Phos-tag gels.

A. Smolenski, Lorna O'Donoghue, 2022, Journal of proteomics.

Phosphodiesterases link the aryl hydrocarbon receptor complex to cyclic nucleotide signaling.

A. Smolenski, Simone Kobe de Oliveira, 2009, Biochemical pharmacology.