W. van den Berg

发表

Role of Fc receptor gamma chain in inflammation and cartilage damage during experimental antigen-induced arthritis.

L. van de Putte, J. V. D. van de Winkel, P. van Lent, 2000, Arthritis and rheumatism.

OP0152 Synovial Macrophages Promote TGF-β Signaling After Intra-Articular Injections of Oxidized LDL in Naïve Murine Knee Joints, Preventing Production of Pro-Inflammatory Factors S100A8/9, Chemokines and Aggrecanase-Induced Neo-Epitopes

T. Vogl, J. Roth, P. M. van der Kraan, 2015 .

Cleavage of aggrecan at the Asn341-Phe342 site coincides with the initiation of collagen damage in murine antigen-induced arthritis: a pivotal role for stromelysin 1 in matrix metalloproteinase activity.

J. V. van Meurs, J. Mudgett, P. Buma, 1999, Arthritis and rheumatism.

Toll-like receptor 4 induced FcγR expression potentiates early onset of joint inflammation and cartilage destruction during immune complex arthritis: Toll-like receptor 4 largely regulates FcγR expression by interleukin 10

A. Blom, P. V. van Lent, A. Sloetjes, 2006, Annals of the rheumatic diseases.

Interleukin-1 is essential for systemic inflammatory bone loss

J. Smolen, J. Zwerina, G. Schett, 2009, Annals of the rheumatic diseases.

Inducible chondrocyte-specific overexpression of BMP2 in young mice results in severe aggravation of osteophyte formation in experimental OA without altering cartilage damage

F. van de Loo, A. V. van Caam, E. Vitters, 2013, Annals of the rheumatic diseases.

Prophylactic treatment with S100A9 inhibitor paquinimod reduces pathology in experimental collagenase-induced osteoarthritis

T. Leanderson, T. Vogl, J. Roth, 2015, Annals of the rheumatic diseases.

Adenoviral overexpression of Smad-7 and Smad-6 differentially regulates TGF-beta-mediated chondrocyte proliferation and proteoglycan synthesis.

P. M. van der Kraan, E. Vitters, H. V. Beuningen, 2003, Osteoarthritis and cartilage.

Coordinate expression of activating Fc gamma receptors I and III and inhibiting Fc gamma receptor type II in the determination of joint inflammation and cartilage destruction during immune complex-mediated arthritis.

S. Verbeek, J. Roth, A. Blom, 2003, Arthritis and rheumatism.

Dendritic cells from patients with rheumatoid arthritis lack the interleukin 13 mediated increase of FcγRII expression, which has clear functional consequences

T. Radstake, P. Barrera, T. Radstake, 2005, Annals of the rheumatic diseases.

FcγRI Up-Regulation Induced by Local Adenoviral-Mediated Interferon-γ Production Aggravates Chondrocyte Death during Immune Complex-Mediated Arthritis

K. Nabbe, S. Verbeek, J. Kolls, 2003 .

Skewed balance in basal expression and regulation of activating v inhibitory Fcγ receptors in macrophages of collagen induced arthritis sensitive mice

A. Blom, C. Jacobs, P. van Lent, 2003, Annals of the rheumatic diseases.

Liposomal targeting of glucocorticoids to synovial lining cells strongly increases therapeutic benefit in collagen type II arthritis

M. Wauben, G. Storm, J. Metselaar, 2004, Annals of the rheumatic diseases.

Cytosolic phospholipase A2α gene silencing in the myeloid lineage alters development of Th1 responses and reduces disease severity in collagen-induced arthritis.

D. Scherman, C. Jorgensen, V. Escriou, 2011, Arthritis and rheumatism.

Cytosolic phospholipase A2α gene silencing in monocytes alters development of Th1 responses and reduces autoimmune arthritis

D. Scherman, C. Jorgensen, V. Escriou, 2010, Journal of Translational Medicine.

IL-4 gene therapy for collagen arthritis suppresses synovial IL-17 and osteoprotegerin ligand and prevents bone erosion.

L. Joosten, L. Joosten, P. Miossec, 2000, The Journal of clinical investigation.

High production of proinflammatory and Th1 cytokines by dendritic cells from patients with rheumatoid arthritis, and down regulation upon FcγR triggering

G. Adema, T. Radstake, P. Barrera, 2004 .

Biphasic decline/increase for anticitrulline and monophasic decline in anti-type II collagen antibody levels in recently diagnosed RA patients

L. Joosten, J. Lampa, Lars Klareskog, 2003, Arthritis Research & Therapy.

W. Nacken, T. Vogl, J. Roth, 2007, Annals of the rheumatic diseases.

Role of activatory Fc gamma RI and Fc gamma RIII and inhibitory Fc gamma RII in inflammation and cartilage destruction during experimental antigen-induced arthritis.

S. Verbeek, L. van de Putte, P. van Lent, 2001, The American journal of pathology.

Local overexpression of adeno-viral IL-4 protects cartilage from metallo proteinase-induced destruction during immune complex-mediated arthritis by preventing activation of pro-MMPs.

E. Lubberts, P. V. van Lent, A. Holthuysen, 2002, Osteoarthritis and cartilage.

Active matrix metalloproteinases are present in cartilage during immune complex-mediated arthritis: a pivotal role for stromelysin-1 in cartilage destruction.

J. V. van Meurs, I. Singer, P. V. van Lent, 1999, Journal of immunology.

Stimulation of chondrocyte-mediated cartilage destruction by S100A8 in experimental murine arthritis.

W. Nacken, H. Freeze, T. Vogl, 2008, Arthritis and rheumatism.

Adenoviral vector-mediated overexpression of IL-4 in the knee joint of mice with collagen-induced arthritis prevents cartilage destruction.

J. V. van Meurs, L. Joosten, F. Graham, 1999, Journal of immunology.

P086 Systemic overexpression of interleukin-22 induces expression of the negative immune-regulator SOCS3 and potently reduces collagen-induced arthritis in mice

B. Walgreen, P. V. van Lent, F. V. D. van de Loo, 2019, Abstracts.

A4.1 Synovial macrophages promote TGF-β signalling after intra-articular injections of oxidised LDL in naÏve murine knee joints, preventing production of pro-inflammatory factors S100A8/9, chemokines and aggrecanase-induced neo-epitopes

T. Vogl, J. Roth, P. van Lent, 2015 .

TGF-β is a potent inducer of Nerve Growth Factor in articular cartilage via the ALK5-Smad2/3 pathway. Potential role in OA related pain?

M. Koenders, F. V. D. van de Loo, P. M. van der Kraan, 2015, Osteoarthritis and cartilage.

Expression and localisation of the new metalloproteinase inhibitor RECK (reversion inducing cysteine-rich protein with Kazal motifs) in inflamed synovial membranes of patients with rheumatoid arthritis

C. Sweep, P. Span, J. Heuvel, 2004, Annals of the rheumatic diseases.

Differential effect of transforming growth factor beta on freshly isolated and cultured articular chondrocytes.

P. M. van der Kraan, E. Vitters, W. van den Berg, 1992, The Journal of rheumatology.

Reduced transforming growth factor-beta signaling in cartilage of old mice: role in impaired repair capacity

E. Vitters, W. van den Berg, A. Scharstuhl, 2005, Arthritis research & therapy.

The expression of toll-like receptors 3 and 7 in rheumatoid arthritis synovium is increased and costimulation of toll-like receptors 3, 4, and 7/8 results in synergistic cytokine production by dendritic cells.

L. Joosten, F. V. D. van den Hoogen, L. Joosten, 2005, Arthritis and rheumatism.

The natural soluble form of IL-18 receptor β exacerbates collagen-induced arthritis via modulation of T-cell immune responses

L. Joosten, R. Smeets, F. van de Loo, 2009, Annals of the rheumatic diseases.

Synovial macrophages promote TGF-β signaling and protect against influx of S100A8/S100A9-producing cells after intra-articular injections of oxidized low-density lipoproteins.

T. Vogl, L. Joosten, J. Roth, 2016, Osteoarthritis and cartilage.

A novel role for suppressor of cytokine signaling 3 in cartilage destruction via induction of chondrocyte desensitization toward insulin-like growth factor.

R. Smeets, F. V. D. van de Loo, S. Veenbergen, 2006, Arthritis and rheumatism.

Alarmins S100A8/S100A9 aggravate osteophyte formation in experimental osteoarthritis and predict osteophyte progression in early human symptomatic osteoarthritis

F. Lafeber, T. Vogl, J. Roth, 2014, Annals of the rheumatic diseases.

Association between serum levels of the proinflammatory protein S100A8/A9 and clinical and structural characteristics of patients with established knee, hip, and hand osteoarthritis

T. Vogl, J. Bijlsma, J. Roth, 2015, Scandinavian journal of rheumatology.

Increased FcγRII expression and aberrant tumour necrosis factor α production by mature dendritic cells from patients with active rheumatoid arthritis

C. Figdor, G. Adema, P. Barrera, 2004, Annals of the rheumatic diseases.

High LDL levels lead to increased synovial inflammation and accelerated ectopic bone formation during experimental osteoarthritis.

K. Croce, T. Vogl, J. Roth, 2016, Osteoarthritis and cartilage.

AB0101 Viral Expression of TSG-6 Can Stimulate Osteophyte Formation in Experimental Osteoarthritis

A. Blom, F. V. D. van de Loo, M. Bennink, 2015 .

Expression of Toll-like receptor (TLR) 2, TLR3, TLR4 and TLR7 is increased in rheumatoid arthritis synovium and regulates cytokine production by dendritic cells upon stimulation of TLR specific pathways

L. Joosten, T. Radstake, S. Abdollahi-Roodsaz, 2005, Arthritis Research & Therapy.

Combined blockade of granulocyte-macrophage colony stimulating factor and interleukin 17 pathways potently suppresses chronic destructive arthritis in a tumour necrosis factor α-independent mouse model

P. Baeuerle, W. B. van den Berg, L. Joosten, 2008, Annals of the rheumatic diseases.

Requirement of local synovial IL-17 receptor signaling in the progression of chronic synovitis and bone erosion in arthritis

J. Peschon, P. Schwarzenberger, E. Lubberts, 2004 .

Potential new targets in arthritis therapy: interleukin (IL)-17 and its relation to tumour necrosis factor and IL-1 in experimental arthritis

W. B. van den Berg, M. Koenders, L. Joosten, 2006, Annals of the rheumatic diseases.