H. van der Linde

发表

Do in vitro assays in rat primary neurons predict drug‐induced seizure liability in humans?

H. R. Lu, A. de Bondt, M. Kreir, 2018, Toxicology and applied pharmacology.

The fentanyl/etomidate-anaesthetised beagle (FEAB) dog: a versatile in vivo model in cardiovascular safety research.

F. Cools, D. Gallacher, K. van Ammel, 2009, Journal of pharmacological and toxicological methods.

Electromechanical reciprocity and arrhythmogenesis in long-QT syndrome and beyond

M. Ackerman, P. Volders, K. Odening, 2022, European heart journal.

The Fentanyl/Etomidate‐Anesthetized Beagle (FEAB) Model in Safety Pharmacology Assessment

D. Gallacher, A. Teisman, B. V. Deuren, 2011, Current protocols in pharmacology.

IKs inhibitor JNJ303 prolongs the QT interval and perpetuates arrhythmia when combined with enhanced inotropy in the CAVB dog.

M. Vos, M. A. van der Heyden, H. Beekman, 2022, European journal of pharmacology.

Torcetrapib Produces Endothelial Dysfunction Independent of Cholesteryl Ester Transfer Protein Inhibition

M. Connelly, F. Cools, D. Gallacher, 2009, Journal of cardiovascular pharmacology.

Seizure-induced Torsades de pointes:In a canine drug-induced long-QT1 model.

M. Kreir, D. Gallacher, A. Teisman, 2021, Journal of pharmacological and toxicological methods.

Blockade of the I(Ks) potassium channel: an overlooked cardiovascular liability in drug safety screening?

Ard Teisman, J. Linders, J. Rohrbacher, 2009, Journal of pharmacological and toxicological methods.

Interventricular Differences in β‐Adrenergic Responses in the Canine Heart: Role of Phosphodiesterases

P. Volders, R. Fischmeister, G. Vandecasteele, 2014, Journal of the American Heart Association.

Diastolic Spontaneous Calcium Release From the Sarcoplasmic Reticulum Increases Beat-to-Beat Variability of Repolarization in Canine Ventricular Myocytes After &bgr;-Adrenergic Stimulation

Najah Abi-Gerges, Paul G A Volders, Jordi Heijman, 2013, Circulation research.

Variability of non-clinical behavioral CNS safety assessment: An intercompany comparison.

M. Deurinck, M. Traebert, A. Delaunois, 2019, Journal of pharmacological and toxicological methods.

Characterization of an anesthetized dog model of transient cardiac ischemia and rapid pacing: a pilot study for preclinical assessment of the potential for proarrhythmic risk of novel drug candidates.

D. Gallacher, B. Damiano, M. Lubomirski, 2015, Journal of pharmacological and toxicological methods.

In vivo mechanisms precipitating torsades de pointes in a canine model of drug-induced long-QT1 syndrome.

Paul G A Volders, P. Volders, Hua-rong Lu, 2007, Cardiovascular research.

The Potential Mechanisms behind Loperamide-Induced Cardiac Arrhythmias Associated with Human Abuse and Extreme Overdose

M. Kreir, Hua-rong Lu, J. Rohrbacher, 2023, Biomolecules.

Diastolic Spontaneous Calcium Release From the Sarcoplasmic Reticulum Increases Beat-to-Beat Variability of Repolarization in Canine Ventricular Myocytes After &bgr;-Adrenergic Stimulation

P. Volders, J. Heijman, A. Trafford, 2013, Circulation research.