Maruja Lira

发表

Comprehensive analysis of RET and ROS1 rearrangement in lung adenocarcinoma

Boram Lee, Yoon-La Choi, Joungho Han, 2015, Modern Pathology.

Correction: A Novel SND1-BRAF Fusion Confers Resistance to c-Met Inhibitor PF-04217903 in GTL16 Cells though MAPK Activation

Yongjun Zhao, S. Aparicio, P. Rejto, 2012, PLoS ONE.

Molecular Predictors of Sensitivity to the Insulin-like Growth Factor 1 Receptor Inhibitor Figitumumab (CP-751,871)

P. Rejto, K. Ching, A. Pavlícek, 2013, Molecular Cancer Therapeutics.

Comprehensive Characterization of Oncogenic Drivers in Asian Lung Adenocarcinoma

Hancheng Zheng, Xiao Liu, Zhuolin Gong, 2016, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

TNER: A Novel Bayesian Background Error Suppression Method for Mutation Detection in Circulating Tumor DNA

Tao Xie, J. Bienkowska, Shibing Deng, 2017, bioRxiv.

Biomarker and Pharmacologic Evaluation of the γ-Secretase Inhibitor PF-03084014 in Breast Cancer Models

P. Rejto, A. Pavlícek, J. Christensen, 2012, Clinical Cancer Research.

Cholesteryl Ester Transfer Protein Variants Have Differential Stability but Uniform Inhibition by Torcetrapib*

Johnf . Thompson, P. Milos, A. Lanzetti, 2005, Journal of Biological Chemistry.

A Novel Fusion of TPR and ALK in Lung Adenocarcinoma

H. Peckham, Zongli Zheng, Joungho Han, 2014, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

CETP polymorphisms associated with HDL cholesterol may differ from those associated with cardiovascular disease.

Johnf . Thompson, C. Shear, P. Milos, 2005, Atherosclerosis.

Genetic Association of the CCR5 Region With Lipid Levels in At-Risk Cardiovascular Patients

Diederik F Van Wijk, R. Mazzarella, Johnf . Thompson, 2010, Circulation. Cardiovascular genetics.

Novel variants in human and monkey CETP.

D. Knight, L. Wood, Maruja Lira, 2005, Biochimica et biophysica acta.

Polymorphisms in the CETP gene and association with CETP mass and HDL levels.

Johnf . Thompson, P. Milos, L. Durham, 2003, Atherosclerosis.

Cholesterol 7α hydroxylase promoter separated from cyclophilin pseudogene by Alu sequence

Johnf . Thompson, Maruja Lira, L. Hayes, 1993 .

Cancer Therapy : Preclinical Biomarker and Pharmacologic Evaluation of the g-Secretase Inhibitor PF-03084014 in Breast Cancer Models

P. Rejto, A. Pavlícek, J. Christensen, 2012 .

Droplet digital polymerase chain reaction detection of HER2 amplification in formalin fixed paraffin embedded breast and gastric carcinoma samples.

H. Chung, Dan Lu, Maruja Lira, 2016, Experimental and molecular pathology.

Highly polymorphic repeat region in the CETP promoter induces unusual DNA structure.

Johnf . Thompson, P. Milos, Maruja Lira, 2004, Biochimica et biophysica acta.

[18F]FLT–PET Imaging Does Not Always “Light Up” Proliferating Tumor Cells

J. Christensen, K. Zasadny, M. Spilker, 2011, Clinical Cancer Research.

Noninvasive saliva-based EGFR gene mutation detection in patients with lung cancer.

Chung-Liang Ho, D. Chia, Ziding Feng, 2014, American journal of respiratory and critical care medicine.

A single-tube multiplexed assay for detecting ALK, ROS1, and RET fusions in lung cancer.

Shibing Deng, M. Ahn, Joungho Han, 2014, The Journal of molecular diagnostics : JMD.

Crystal structure of cholesteryl ester transfer protein reveals a long tunnel and four bound lipid molecules

Ing-Kae Wang, Xiayang Qiu, Dennis E Danley, 2007, Nature Structural &Molecular Biology.

CYP2D6 Genotyping as an alternative to phenotyping for determination of metabolic status in a clinical trial setting

J. Brockmöller, P. Milos, I. Roots, 2000, AAPS PharmSci.

Combined gemcitabine and CHK1 inhibitor treatment induces apoptosis resistance in cancer stem cell-like cells enriched with tumor spheroids from a non-small cell lung cancer cell line

Zhou Zhu, A. Blasina, T. Vanarsdale, 2013, Frontiers of Medicine.

An Integrated Genomic Approach to Identify Predictive Biomarkers of Response to the Aurora Kinase Inhibitor PF-03814735

Paul A. Rejto, Jing Yuan, Keith A. Ching, 2012, Molecular Cancer Therapeutics.

Multiplexed transcriptome analysis to detect ALK, ROS1 and RET rearrangements in lung cancer

Gisela Mir Arnau, S. Fox, Toni-Maree Rogers, 2017, Scientific Reports.

HIP1–ALK, A Novel ALK Fusion Variant that Responds to Crizotinib

J. Christensen, Q. Gu, Bin Zhang, 2014, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

PIK3CA mutation detection in metastatic biliary cancer using cell-free DNA

Joon-Oh Park, Shibing Deng, W. Kwon, 2015, Oncotarget.

A Novel SND1-BRAF Fusion Confers Resistance to c-Met Inhibitor PF-04217903 in GTL16 Cells though MAPK Activation

Yongjun Zhao, S. Aparicio, P. Rejto, 2012, PloS one.

HIP1–ALK, a Novel Fusion Protein Identified in Lung Adenocarcinoma

Joungho Han, Jhingook Kim, M. Hong, 2014, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

Multiplexed gene expression and fusion transcript analysis to detect ALK fusions in lung cancer.

Shibing Deng, J. Ahn, M. Ahn, 2013, The Journal of molecular diagnostics : JMD.

Initial clinical sensitivity and acquired resistance to MET inhibition in MET-mutated papillary renal cell carcinoma.

Jeffrey W. Clark, K. Ching, J. Christensen, 2013, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Lung cancer in never-smoker Asian females is driven by oncogenic mutations, most often involving EGFR

Y. Shim, Xinyu Liu, Jhingook Kim, 2015, Oncotarget.

Expression of CETP and of splice variants induces the same level of ER stress despite secretion efficiency differences Published, JLR Papers in Press, May 28, 2008.

S. Paciga, A. Loomis, Maruja Lira, 2008, Journal of Lipid Research.

Synergistic Effect of the γ‐Secretase Inhibitor PF‐03084014 and Docetaxel in Breast Cancer Models

J. Christensen, C. Painter, Maruja Lira, 2013, Stem cells translational medicine.

SEC31A-ALK Fusion Gene in Lung Adenocarcinoma

Joungho Han, Jhingook Kim, Mi-Sook Lee, 2015, Cancer research and treatment : official journal of Korean Cancer Association.

Identification of a novel partner gene, KIAA1217, fused to RET: Functional characterization and inhibitor sensitivity of two isoforms in lung adenocarcinoma

Joungho Han, Jhingook Kim, Yoon-La Choi, 2016, Oncotarget.

Abstract 4504: PF-04449913, a small molecule inhibitor of Hedgehog signaling, is effective in inhibiting tumor growth in preclinical models

Zhou Zhu, R. Schwab, M. Munchhof, 2011 .

TNER: a novel background error suppression method for mutation detection in circulating tumor DNA

Tao Xie, Kai Wang, Shibing Deng, 2018, BMC Bioinformatics.

Clinical characteristics associated with ALK rearrangements in never-smokers with pulmonary adenocarcinoma.

J. Ahn, M. Ahn, Keunchil Park, 2014, Lung cancer.

TNER: a novel background error suppression method for mutation detection in circulating tumor DNA

J. Bienkowska, Shibing Deng, P. Rejto, 2018, BMC Bioinformatics.

Abstract 2615: Amplification and/or high expression of Myc family genes sensitizes tumor cells to aurora kinase inhibitors

K. Ching, A. Pavlícek, J. Christensen, 2010 .

Noninvasive saliva-based EGFR gene mutation detection in patients with lung cancer.

Chung-Liang Ho, D. Chia, Ziding Feng, 2014, American journal of respiratory and critical care medicine.