R. Tanimura

发表

Determinants of protein side‐chain packing

A. Kidera, H. Nakamura, A Kidera, 1994, Protein science : a publication of the Protein Society.

Interaction between the Amino-terminal SH3 Domain of CRK and Its Natural Target Proteins*

Haruki Nakamura, T. Takenawa, M. Matsuda, 1996, The Journal of Biological Chemistry.

Discovery of attenuation effect of orexin 1 receptor to aversion of nalfurafine: Synthesis and evaluation of D-nor-nalfurafine derivatives and analyses of the three active conformations of nalfurafine.

M. Yanagisawa, Y. Nagumo, Y. Irukayama-Tomobe, 2020, Bioorganic & medicinal chemistry letters.

Essential structure of orexin 1 receptor antagonist YNT-707: Conversion of the 16-cyclopropylmethyl group to the 16-sulfonamide group in D-nor-nalfurafine derivatives

M. Yanagisawa, Y. Nagumo, Y. Irukayama-Tomobe, 2022, Bioorganic & Medicinal Chemistry Letters.

Relaxing Substrate Specificity in Antibody-Catalyzed Reactions: Enantioselective Hydrolysis of N-Cbz-Amino Acid Esters

F. Tanaka, I. Fujii, R. Tanimura, 1996 .

Site-directed mutagenesis of active site contact residues in a hydrolytic abzyme: evidence for an essential histidine involved in transition state stabilization.

C. Cagnon, H. Miyashita, S. Fukuyama, 1997, Journal of molecular biology.

Discovery of highly selective κ-opioid receptor agonists: 10α-Hydroxy TRK-820 derivatives.

R. Tanimura, Yuji Sugawara, K. Kawai, 2017, Bioorganic & medicinal chemistry letters.

Discovery of novel orexin receptor antagonists using a 1,3,5-trioxazatriquinane bearing multiple effective residues (TriMER) library.

T. Sakurai, M. Yanagisawa, H. Gouda, 2021, European journal of medicinal chemistry.

(cid:1) 1 -Selective Agonist ( (cid:1) )-1-(3,4-Dimethoxyphenetylamino)-3-(3,4-dihydroxy)-2-propanol [( (cid:1) )-RO363] Differentially Interacts with Key Amino Acids Responsible for (cid:1) 1 -Selective Binding in Resting and Active States

G. Tsujimoto, T. Nagao, H. Kurose, 2002 .

Essential structure of orexin 1 receptor antagonist YNT-707, Part IV: The role of D-ring in 4,5-epoxymorphinan on the orexin 1 receptor antagonistic activity.

M. Yanagisawa, Y. Nagumo, Y. Irukayama-Tomobe, 2019, Bioorganic & medicinal chemistry letters.

A NOVEL ABNORMAL REARRANGEMENT IN THE FISCHER INDOLE SYNTHESIS

H. Nagase, R. Tanimura, H. Fujii, 1997 .

Correlation between Antigen-Combining-Site Structures and Functions within a Panel of Catalytic Antibodies Generated against a Single Transition State Analog

Ikuo Fujii, Hideaki Miyashita, Ryuji Tanimura, 1995 .

Evolving catalytic antibodies in a phage-displayed combinatorial library

S. Fukuyama, I. Fujii, Y. Iwabuchi, 1998, Nature Biotechnology.

Structural basis for platelet antiaggregation by angiotensin II type 1 receptor antagonist losartan (DuP-753) via glycoprotein VI.

K. Ono, I. Shimada, Hideo Takahashi, 2010, Journal of medicinal chemistry.

Structural and Interaction Analysis of Glycoprotein VI-binding Peptide Selected from a Phage Display Library*

K. Ono, I. Shimada, Hideo Takahashi, 2009, Journal of Biological Chemistry.

Binding pockets of the beta(1)- and beta(2)-adrenergic receptors for subtype-selective agonists.

H. Kikkawa, T. Nagao, H. Kurose, 1999, Molecular pharmacology.

Solution structure of ferredoxin from the thermophilic cyanobacterium Synechococcus elongatus and its thermostability.

F. Inagaki, H. Hatanaka, S. Katoh, 1997, Journal of molecular biology.

Discovery of Orexin 2 Receptor Selective and Dual Orexin Receptor Agonists based on the Tetralin Structure: Switching of Receptor Selectivity by Chirality on the Tetralin Ring.

M. Yanagisawa, Y. Nagumo, H. Nagase, 2022, Bioorganic & Medicinal Chemistry Letters.

Design and Synthesis of Orexin 1 Receptor-Selective Agonists.

A. Inoue, K. Takeuchi, Y. Nagumo, 2023, Journal of medicinal chemistry.

Unexpected Rearrangement Reactions of the 14-Aminonaltrexone Skeleton.

Y. Nagumo, H. Nagase, Tsuyoshi Saitoh, 2023, Organic letters.

Comparative analysis of electronic states of saturated dioxa and dithia heterocycles and their radical cations

T. Momose, K. Ushida, R. Tanimura, 1987 .

Multiple binding modes of a small molecule to human Keap1 revealed by X-ray crystallography and molecular dynamics simulation

H. Naitow, N. Kunishima, Y. Matsuura, 2015, FEBS open bio.

Beta(1)-selective agonist (-)-1-(3,4-dimethoxyphenetylamino)-3-(3,4-dihydroxy)-2-propanol [(-)-RO363] differentially interacts with key amino acids responsible for beta(1)-selective binding in resting and active states.

G. Tsujimoto, T. Nagao, H. Kurose, 2002, The Journal of pharmacology and experimental therapeutics.

Design and synthesis of novel orexin 2 receptor agonists based on naphthalene skeleton.

M. Yanagisawa, Y. Nagumo, H. Nagase, 2021, Bioorganic & medicinal chemistry letters.

Effect of removal of the 14-hydroxy group on the affinity of the 4,5-epoxymorphinan derivatives for orexin and opioid receptors.

M. Yanagisawa, Y. Nagumo, H. Nagase, 2022, Bioorganic & medicinal chemistry letters.

Structure-based approach to improve a small-molecule inhibitor by the use of a competitive peptide ligand.

K. Ono, I. Shimada, Hideo Takahashi, 2014, Angewandte Chemie.

Side-chain Conformations Cooperatively Restricted in Protein Secondary Structure

Haruki Nakamura, A. Kidera, R. Tanimura, 1996 .

Side-chain Conformations Cooperatively Restricted in Protein Secondary Structure. II. Side-chain Configurational Entropies of .ALPHA.-helices in the Folding Nuclei.

Haruki Nakamura, A. Kidera, R. Tanimura, 1996 .