W. Jia

发表

Hierarchical protein folding: asymmetric unfolding of an insulin analogue lacking the A7-B7 interchain disulfide bridge.

M. Weiss, P. Katsoyannis, Q. Hua, 2001, Biochemistry.

A cavity-forming mutation in insulin induces segmental unfolding of a surrounding alpha-helix.

M. Weiss, P. Katsoyannis, Q. Hua, 2002, Protein science : a publication of the Protein Society.

Activities of Insulin Analogues at Position A8 are Uncorrelated with Thermodynamic Stability

M. Weiss, P. Katsoyannis, Q. Hua, 2002 .

Non-standard insulin design: structure-activity relationships at the periphery of the insulin receptor.

M. Weiss, P. Katsoyannis, S. Nakagawa, 2002, Journal of molecular biology.

Chiral Mutagenesis of Insulin

M. Weiss, P. Katsoyannis, Q. Hua, 2006, Journal of Biological Chemistry.

Chiral mutagenesis of insulin. Foldability and function are inversely regulated by a stereospecific switch in the B chain.

M. Weiss, Q. Hua, S. Nakagawa, 2005, Biochemistry.

Design of an Active Ultrastable Single-chain Insulin Analog

Kun Huang, Wenhua Jia, Satoe H. Nakagawa, 2008, Journal of Biological Chemistry.

Chiral mutagenesis of insulin's hidden receptor-binding surface: structure of an allo-isoleucine(A2) analogue.

M. Weiss, P. Katsoyannis, Q. Hua, 2002, Journal of molecular biology.

Mini-proinsulin and mini-IGF-I: homologous protein sequences encoding non-homologous structures.

M. Weiss, S. H. Wang, R. Y. Wang, 1998, Journal of molecular biology.

A protein caught in a kinetic trap: structures and stabilities of insulin disulfide isomers.

M. Weiss, B. Frank, Q. Hua, 2002, Biochemistry.

Mapping the functional surface of insulin by design: structure and function of a novel A-chain analogue.

M. Weiss, S. H. Wang, B. Frank, 1996, Journal of molecular biology.

Diabetes mellitus due to misfolding of a β-cell transcription factor : Stereospecific frustration of a schellman motif in HNF-1α

Wenhua Jia, M. Weiss, N. Phillips, 2006 .

Diabetes-associated mutations in a beta-cell transcription factor destabilize an antiparallel "mini-zipper" in a dimerization interface.

M. Weiss, Q. Hua, S. Nakagawa, 2000, Proceedings of the National Academy of Sciences of the United States of America.

The A-chain of Insulin Contacts the Insert Domain of the Insulin Receptor

D. Steiner, M. Weiss, P. De Meyts, 2007, Journal of Biological Chemistry.

Protein structure and the spandrels of San Marco: insulin's receptor-binding surface is buttressed by an invariant leucine essential for its stability.

M. Weiss, P. Katsoyannis, Q. Hua, 2002, Biochemistry.

Native and non-native structure in a protein-folding intermediate: spectroscopic studies of partially reduced IGF-I and an engineered alanine model.

R Rosenfeld, J A Miller, J. Miller, 1996, Journal of molecular biology.

Enhancing the Activity of a Protein by Stereospecific Unfolding

M. Weiss, J. Whittaker, P. Katsoyannis, 2009, Journal of Biological Chemistry.

A divergent INS protein in Caenorhabditis elegans structurally resembles human insulin and activates the human insulin receptor.

M. Weiss, J. Bass, J. Wilken, 2003, Genes & development.

The Folding Nucleus of the Insulin Superfamily

J. Mayer, M. Weiss, Q. Hua, 2006, Journal of Biological Chemistry.

Deciphering the Hidden Informational Content of Protein Sequences

P. Arvan, M. Weiss, Ming Liu, 2010, The Journal of Biological Chemistry.

Toward the Active Conformation of Insulin

M. Weiss, Q. Hua, S. Nakagawa, 2006, Journal of Biological Chemistry.

Conformational Dynamics of Insulin

M. Weiss, Q. Hua, W. Jia, 2011, Front. Endocrin..

Mechanism of Insulin Chain Combination

M. Weiss, N. Phillips, P. Katsoyannis, 2002, The Journal of Biological Chemistry.

Activities of Monomeric Insulin Analogs at Position A8 Are Uncorrelated with Their Thermodynamic Stabilities*

M. Weiss, M A Weiss, Q X Hua, 2001, The Journal of Biological Chemistry.

A Conserved Histidine in Insulin Is Required for the Foldability of Human Proinsulin

P. Arvan, M. Weiss, Ming Liu, 2006, Journal of Biological Chemistry.

Hierarchical protein "un-design": insulin's intrachain disulfide bridge tethers a recognition alpha-helix.

M. Weiss, R. Y. Wang, P. Katsoyannis, 2000, Biochemistry.

A cavity‐forming mutation in insulin induces segmental unfolding of a surrounding α‐helix

Wenhua Jia, Satoe H. Nakagawa, M. Weiss, 2002 .

Diabetes mellitus due to misfolding of a beta-cell transcription factor: stereospecific frustration of a Schellman motif in HNF-1alpha.

Wenhua Jia, Michael A Weiss, M. Weiss, 2006, Journal of molecular biology.

ENHANCING THE ACTIVITY OF INSULIN BY STEREOSPECIFIC UNFOLDING

M. Weiss, P. Katsoyannis, Q. Hua, 2008 .

Transcriptional activator-coactivator recognition: nascent folding of a kinase-inducible transactivation domain predicts its structure on coactivator binding.

J. Habener, Q. Hua, W. Jia, 1998, Biochemistry.

ENHANCING THE ACTIVITY OF INSULIN BY STEREOSPECIFIC UNFOLDING

M. Weiss, P. Katsoyannis, Q. Hua, 2008 .