D. Upmalis

发表

Tapentadol hydrochloride: a next-generation, centrally acting analgesic with two mechanisms of action in a single molecule.

K. Schiene, T. Tzschentke, W. Englberger, 2009, Drugs of today.

A comparison study of lipid and androgen metabolism with triphasic oral contraceptive formulations containing norgestimate or levonorgestrel

D. Upmalis, M. Dain, J. Rouffy, 1992, Acta obstetricia et gynecologica Scandinavica. Supplement.

Post hoc analyses of data from a 90-day clinical trial evaluating the tolerability and efficacy of tapentadol immediate release and oxycodone immediate release for the relief of moderate to severe pain in elderly and nonelderly patients.

D. Biondi, J. Delfgaauw, J. Xiang, 2011, Pain research & management.

Evaluation of study discontinuations with tapentadol inmmediate release and oxycodone immediate release in patients with low back or osteoarthritis pain.

J. Xiang, A. Okamoto, D. Upmalis, 2010, Journal of opioid management.

Tolerability of tapentadol immediate release in patients with lower back pain or osteoarthritis of the hip or knee over 90 days: a randomized, double-blind study*

C. Rauschkolb, A. Okamoto, D. Upmalis, 2009 .

Review of the endometrial effects of estrogens and progestins.

M. Kafrissen, D. Upmalis, G. Creasy, 1992, Obstetrical & gynecological survey.

Vasomotor Symptom Relief by Soy Isoflavone Extract Tablets in Postmenopausal Women: A Multicenter, Double‐Blind, Randomized, Placebo‐Controlled Study

R. Lobo, M. Warren, D. Upmalis, 2000, Menopause.

A randomized, double-blind, placebo-controlled phase 3 study of the relative efficacy and tolerability of tapentadol IR and oxycodone IR for acute pain

S. Daniels, C. Rauschkolb, J. Stegmann, 2009, Current medical research and opinion.

Comparison of endometrial growth produced by unopposed conjugated estrogens or by micronized estradiol in postmenopausal women.

B. Ettinger, D. Upmalis, J. T. Citron, 1997, American journal of obstetrics and gynecology.

A randomized, double-blind, phase III study comparing multiple doses of tapentadol IR, oxycodone IR, and placebo for postoperative (bunionectomy) pain*

S. Daniels, A. Okamoto, D. Upmalis, 2009, Current medical research and opinion.

The efficacy and tolerability of multiple-dose tapentadol immediate release for the relief of acute pain following orthopedic (bunionectomy) surgery*

J. Stegmann, A. Okamoto, D. Upmalis, 2008, Current medical research and opinion.

Dovepress Open Access to Scientific and Medical Research Open Access Full Text Article Tapentadol Immediate Release: a New Treatment Option for Acute Pain Management

M. Afilalo, J. Stegmann, D. Upmalis, 2022 .

Bioavailability Study of a 1200 mg Miconazole Nitrate Vaginal Ovule in Healthy Female Adults

P. Desai, R. E. Stevens, J. Konsil, 2002, Journal of clinical pharmacology.

Single-dose miconazole nitrate vaginal ovule in the treatment of vulvovaginal candidiasis: two single-blind, controlled studies versus miconazole nitrate 100 mg cream for 7 days.

D. Upmalis, G. Rodriguez-gomez, F. Cone, 2000, Journal of Womens Health & Gender-Based Medicine.

Effects of Acetaminophen, Naproxen, and Acetylsalicylic Acid on Tapentadol Pharmacokinetics: Results of Two Randomized, Open‐Label, Crossover, Drug‐Drug Interaction Studies

J. Smit, D. Upmalis, R. Terlinden, 2010, Pharmacotherapy.

Clinical evaluation of a new triphasic oral contraceptive: norgestimate and ethinyl estradiol

A. Gauthier, D. Upmalis, M. Dain, 1992, Acta obstetricia et gynecologica Scandinavica. Supplement.

Comparative contraceptive efficacy and mechanism of action of the norgestimate‐containing triphasic oral contraceptive

W. Olson, A. Chapdelaine, D. Upmalis, 1992, Acta obstetricia et gynecologica Scandinavica. Supplement.

Lack of Pharmacokinetic Interaction Between Butorphanol Tartrate Nasal Spray and Sumatriptan Succinate

N. Srinivas, W. Shyu, D. Upmalis, 1995, Journal of clinical pharmacology.

A randomized, double-blind, phase III study comparing multiple doses of tapentadol IR, oxycodone IR, and placebo for postoperative (bunionectomy) pain.

S. Daniels, A. Okamoto, D. Upmalis, 2009, Current medical research and opinion.

The efficacy and tolerability of multiple-dose tapentadol immediate release for the relief of acute pain following orthopedic (bunionectomy) surgery .

J. Stegmann, A. Okamoto, D. Upmalis, 2008, Current medical research and opinion.

Efficacy and tolerability of tapentadol immediate release and oxycodone HCl immediate release in patients awaiting primary joint replacement surgery for end-stage joint disease: a 10-day, phase III, randomized, double-blind, active- and placebo-controlled study.

C. Hartrick, J. Stegmann, D. Upmalis, 2009, Clinical therapeutics.

Tapentadol immediate release for the relief of acute pain following orthopedic surgery of the forefoot: Efficacy and tolerability results from a randomized, double-blind, phase II study: 14AP11-3

J. Stegmann, D. Upmalis, H. Weber, 2008 .

Pharmacokinetic and Pharmacodynamic Modeling of Opioid-Induced Gastrointestinal Side Effects in Patients Receiving Tapentadol IR and Oxycodone IR

P. Nandy, X. Xu, A. Okamoto, 2012, Pharmaceutical Research.

Tolerability of tapentadol immediate release in patients with lower back pain or osteoarthritis of the hip or knee over 90 days: a randomized, double-blind study.

C. Rauschkolb, A. Okamoto, D. Upmalis, 2009, Current medical research and opinion.

Bowel Function After Tapentadol and Oxycodone Immediate Release (IR) Treatment in Patients With Low Back or Osteoarthritis Pain

S. Kavanagh, A. Okamoto, D. Upmalis, 2013, The Clinical journal of pain.

Pharmacokinetic and Pharmacodynamic Modeling of Opioid-Induced Gastrointestinal Side Effects in Patients Receiving Tapentadol IR and Oxycodone IR

P. Nandy, X. Xu, A. Okamoto, 2012, Pharmaceutical Research.

A thorough QT/QTc study of multiple doses of tapentadol immediate release in healthy subjects.

C. Rauschkolb, D. Upmalis, T. Häufel, 2010, International journal of clinical pharmacology and therapeutics.

Pain relief and tolerability balance of immediate release tapentadol or oxycodone treatment for patients with moderate to severe osteoarthritis or low back pain.

W. Nelson, S. Kavanagh, D. Upmalis, 2012, Pain medicine.

ORIGINAL RESEARCH ARTICLES Pain Relief and Tolerability Balance of Immediate Release Tapentadol or Oxycodone Treatment for Patients with Moderate to Severe Osteoarthritis or Low Back Pain

W. Nelson, S. Kavanagh, D. Upmalis, 2016 .

Dose-response relationship after single oral dose administrations of morphine and oxycodone using laser-evoked potentials on UVB- and capsaicin-irritated skin in healthy male subjects

P. Reitmeir, J. Smit, D. Upmalis, 2012, PAIN®.

Bowel function following tapentadol and oxycodone immediate release (IR) Treatment in subjects with end stage joint disease: post-hoc analysis of data from a randomized, double-blind, active- and placebo-controlled study

S. Kavanagh, A. Okamoto, D. Upmalis, 2009 .