S. Ghayad

发表

p53 Restoration in Induction and Maintenance of Senescence: Differential Effects in Premalignant and Malignant Tumor Cells

G. Evan, Z. Nawaz, M. Jabbour, 2015, Molecular and Cellular Biology.

mTOR inhibition reverses acquired endocrine therapy resistance of breast cancer cells at the cell proliferation and gene‐expression levels

I. Bièche, R. Lidereau, C. Dumontet, 2008, Cancer science.

p53 Acts as a Safeguard of Translational Control by Regulating Fibrillarin and rRNA Methylation in Cancer

J. Saurin, A. Thompson, J. Bourdon, 2013, Cancer Cell.

Exosomes derived from embryonal and alveolar rhabdomyosarcoma carry differential miRNA cargo and promote invasion of recipient fibroblasts

C. Chelala, R. Nasr, M. Diab-Assaf, 2016, Scientific Reports.

The histone deacetylase inhibitor Suberoylanilide Hydroxamic Acid (SAHA) as a therapeutic agent in rhabdomyosarcoma

R. Saab, S. Ghayad, Farah Ghamloush, 2018, Cancer biology & therapy.

CDK2 Transcriptional Repression Is an Essential Effector in p53-Dependent Cellular Senescence—Implications for Therapeutic Intervention

G. Evan, R. Saab, N. Ghanem, 2014, Molecular Cancer Research.

ZNF217 confers resistance to the pro-apoptotic signals of paclitaxel and aberrant expression of Aurora-A in breast cancer cells

C. Collins, L. Payen, J. Vendrell, 2010, Molecular Cancer.

The PAX3-FOXO1 oncogene alters exosome miRNA content and leads to paracrine effects mediated by exosomal miR-486

R. Saab, Mohamad Harajly, S. Ghayad, 2019, Scientific Reports.

The synthetic retinoid ST1926 as a novel therapeutic agent in rhabdomyosarcoma

N. Darwiche, C. Pisano, R. Saab, 2016, International journal of cancer.

Lipoic acid decreases breast cancer cell proliferation by inhibiting IGF-1R via furin downregulation

H. Lincet, N. Hussein, N. Gadot, 2020, British Journal of Cancer.

Lipoic acid-induced oxidative stress abrogates IGF-1R maturation by inhibiting the CREB/furin axis in breast cancer cell lines

H. Lincet, N. Hussein, M. Le Romancer, 2020, Oncogene.

gem-Difluorobisarylic derivatives: design, synthesis and anti-inflammatory effect

N. El-Hachem, A. Hachem, B. Badran, 2019, BMC Chemistry.

Non-coding RNA in rhabdomyosarcoma progression and metastasis

P. Clézardin, N. Hussein, P. Cohen, 2022, Frontiers in Oncology.

CD147 Promotes Tumorigenesis via Exosome-Mediated Signaling in Rhabdomyosarcoma

A. Tawil, H. Tamim, B. Badran, 2022, Cells.

The Intricate Interplay between the ZNF217 Oncogene and Epigenetic Processes Shapes Tumor Progression

M. Croset, P. Clézardin, N. Hussein, 2022, Cancers.

Environmental pollutants-dependent molecular pathways and carcinogenesis

P. Cohen, S. Ghayad, M. Diab‐Assaf, 2019, BioDiscovery.

Lipoic acid decreases breast cancer cell proliferation by inhibiting IGF-1R via furin downregulation

H. Lincet, N. Hussein, N. Gadot, 2020, British Journal of Cancer.

Signaling pathways in Rhabdomyosarcoma invasion and metastasis

R. Saab, S. Ghayad, Assil Fahs, 2020, Cancer and Metastasis Reviews.

Identification of TACC1, NOV, and PTTG1 as new candidate genes associated with endocrine therapy resistance in breast cancer.

I. Bièche, R. Lidereau, I. Treilleux, 2008, Journal of molecular endocrinology.

Identification of TACC 1 , NOV , and PTTG 1 as new candidate genes associated with endocrine therapy resistance in breast cancer

I. Bièche, R. Lidereau, I. Treilleux, 2009 .

A20/TNFAIP3, a new estrogen-regulated gene that confers tamoxifen resistance in breast cancer cells

C. Dumontet, J. Vendrell, N. Mechti, 2007, Oncogene.

Proteomic profiling of rhabdomyosarcoma-derived exosomes yield insights into their functional role in paracrine signaling.

Y. Mechref, F. Kobeissy, R. Zhu, 2019, Journal of proteome research.

ZNF217 is a marker of poor prognosis in breast cancer that drives epithelial-mesenchymal transition and invasion.

I. Bièche, I. Treilleux, P. Roux, 2012, Cancer research.

Endocrine resistance associated with activated ErbB system in breast cancer cells is reversed by inhibiting MAPK or PI3K/Akt signaling pathways

I. Bièche, C. Dumontet, J. Vendrell, 2010, International journal of cancer.

Evidence for rRNA 2′-O-methylation plasticity: Control of intrinsic translational capabilities of human ribosomes

Yohann Couté, Yuri Motorin, Virginie Marchand, 2017, Proceedings of the National Academy of Sciences.

Long-Term Exposure of Early-Transformed Human Mammary Cells to Low Doses of Benzo[a]pyrene and/or Bisphenol A Enhances Their Cancerous Phenotype via an AhR/GPR30 Interplay

B. Győrffy, B. Fervers, J. Lachuer, 2020, Frontiers in Oncology.

Molecular characterization of anastrozole resistance in breast cancer: Pivotal role of the Akt/mTOR pathway in the emergence of de novo or acquired resistance and importance of combining the allosteric Akt inhibitor MK‐2206 with an aromatase inhibitor

I. Treilleux, T. Bachelot, J. Vendrell, 2013, International journal of cancer.

Steroid receptors and associated transcriptional cofactors in predicting the response to endocrine therapy

P. Cohen, S. Ghayad, 2008 .

Oestrogen Non-Genomic Signalling is Activated in Tamoxifen-Resistant Breast Cancer

I. Treilleux, O. Trédan, J. Vendrell, 2019, International journal of molecular sciences.

Inhibitors of the PI3K/Akt/mTOR pathway: new hope for breast cancer patients.

P. Cohen, S. Ghayad, Sandra E Ghayad, 2010, Recent patents on anti-cancer drug discovery.

HSV-1 cellular model reveals links between aggresome formation and early step of Alzheimer’s disease

M. Férréol, C. Helmer, J. Textoris, 2023, Translational Psychiatry.

Effects of the Oncoprotein PAX3-FOXO1 on Modulation of Exosomes Function and Protein Content: Implications on Oxidative Stress Protection and Enhanced Plasticity

Y. Mechref, F. Kobeissy, R. Zhu, 2020, Frontiers in oncology.

Fluorinated Benzofuran and Dihydrobenzofuran as Anti-Inflammatory and Potential Anticancer Agents

A. Hachem, B. Badran, R. Grée, 2023, International journal of molecular sciences.

Signaling pathways in Rhabdomyosarcoma invasion and metastasis

R. Saab, S. Ghayad, Assil Fahs, 2020, Cancer and Metastasis Reviews.

Exosome-Mediated Paracrine Signaling Unveils miR-1246 as a Driver of Aggressiveness in Fusion-Negative Rhabdomyosarcoma

Z. Herceg, B. Badran, R. Saab, 2024, Cancers.