K. Isobe

发表

The maintenance of methylation-free islands in transgenic mice.

A. Kolstø, G. Kollias, F. Grosveld, 1986, Nucleic acids research.

Accelerated development and aging of the immune system in p53-deficient mice.

K. Ohkusu-Tsukada, K. Isobe, T. Tsukada, 1999, Journal of immunology.

Redox‐linked ligand‐independent cell surface triggering for extensive protein tyrosine phosphorylation

K. Isobe, I. Nakashima, T. Iwamoto, 1993, FEBS letters.

Aberrant melanogenesis and melanocytic tumour development in transgenic mice that carry a metallothionein/ret fusion gene.

K. Isobe, I. Nakashima, T. Iwamoto, 1991, The EMBO journal.

Higher expression of topoisomerase II in lung cancers than normal lung tissues: different expression pattern from topoisomerase I.

K. Shimokata, I. Nakashima, K. Isobe, 1993, Biochemical and biophysical research communications.

Cell type-oriented differential modulatory actions of saikosaponin-d on growth responses and DNA fragmentation of lymphocytes triggered by receptor-mediated and receptor-bypassed pathways.

K. Isobe, M. Kato, I. Nakashima, 1995, Immunopharmacology.

Abundant production of nitric oxide from murine macrophages by direct stimulation of tumor cells.

I. Nakashima, K. Isobe, 1993, Biochemical and biophysical research communications.

Nitric oxide as an inflammatory mediator of radiation pneumonitis in rats.

Y. Hasegawa, K. Shimokata, K. Isobe, 1997, The American journal of physiology.

Oncogenicity of the ret transforming gene in MMTV/ret transgenic mice.

K. Isobe, T. Yoshida, I. Nakashima, 1990, Oncogene.

Redox mechanism as alternative to ligand binding for receptor activation delivering disregulated cellular signals.

K. Isobe, I. Nakashima, L. Ma, 1994, Journal of immunology.

Somatic mutation in rearranged IgHV gene of B-NHLs

J. Tamaru, S. Itoyama, K. Isobe, 1999 .

Delivery of an accessory signal for cell activation by exogenous phosphatidylinositol‐specific phospholipase C

R. Taguchi, T. Yoshida, I. Nakashima, 1992, FEBS letters.

Evidence of synergy between Thy-1 and CD3/TCR complex in signal delivery to murine thymocytes for cell death.

R. Taguchi, T. Yoshida, I. Nakashima, 1991, Journal of immunology.

Immunosuppressive activity induced by nitric oxide in culture supernatant of activated rat alveolar macrophages.

T. Kawabe, K. Shimokata, I. Nakashima, 1992, Immunology.

Identification and characterization of a unique tumor-associated surface antigen on L1210 leukemia cells recognized by semisyngeneic antisera.

T. Yokochi, K. Yamada, I. Nakashima, 1987, Cancer research.

Glycyrrhizin as a promoter of the late signal transduction for interleukin-2 production by splenic lymphocytes.

T. Yokochi, M. Kato, I. Nakashima, 1993, Immunology.

Evidence of redox‐linked signaling for producing a giant signal complex

K. Isobe, A. Akhand, I. Nakashima, 1995, Journal of cellular biochemistry.

Bidirectional control by glycyrrhizin of the growth response of lymphocytes stimulated through a receptor-bypassed pathway.

I. Nakashima, T. Iwamoto, K. Isobe, 1992, Immunology letters.

Reinnervation of peripheral nerve segments implanted into the hemisected spinal cord estimated by transgenic mice

H. Iwata, Y. Matsuyama, K. Isobe, 1995, Paraplegia.

Ontogeny of the erythrocyte-dependent IgM antibody responses to cell membrane antigens.

I. Nakashima, F. Nagase, N. Kato, 1984, Developmental and comparative immunology.

Amniotic Fluid Enhances Allogeneic Cytotoxic T Cell Responses, Whereas It Suppresses Mitogen‐Stimulated Lymphocyte Proliferation

K. Isobe, I. Nakashima, S. Goto, 1994, Microbiology and immunology.

Oncogene-linked in situ immunotherapy of pre-B lymphoma arising in E mu/ret transgenic mice.

A. Parashar, K. Isobe, M. Takahashi, 1995, British Journal of Cancer.

Oncogene-linked in situ immunotherapy of pre-B lymphoma arising in E mu/ret transgenic mice.

M. Ichihara, T. Iwamoto, A. Parashar, 1995, British Journal of Cancer.

Further Evaluation of the Pregnancy‐Linked Down‐Regulation of the Paternal Antigen‐Specific Splenic Cytotoxic T Lymphocyte Activity in Allogeneically Pregnant Mice

K. Isobe, I. Nakashima, S. Goto, 1992, Microbiology and immunology.

A possible site of in vivo action of cyclosporin A for transplantation immunity: comparative study with cyclophosphamide.

K. Shimokata, I. Nakashima, F. Nagase, 1991, Immunobiology.

Biphasic radiation-sensitivity of the transplantation immunity for rejection of an allogeneic ascites tumor.

K. Shimokata, T. Yoshida, I. Nakashima, 1988, Immunobiology.

Nitric oxide: a possible etiologic factor in spinal cord cavitation.

H. Iwata, Y. Matsuyama, J. Yano, 1998, Journal of spinal disorders.

Promotion of proliferation of murine hematopoietic stem cells by growth factors in murine amniotic fluid.

I. Nakashima, Z. Heidari, K. Kiuchi, 1996, Journal of reproductive immunology.

Inhibitory effect of bestatin on the growth of human lymphocytes.

I. Nakashima, S. Goto, Y. Tomoda, 1992, Immunopharmacology.

Enhancement of nitric oxide production from activated macrophages by glycyrrhizin.

K. Isobe, I. Nakashima, K. Isobe, 1996, The American journal of Chinese medicine.

Modulation by glycyrrhizin of the cell-surface expression of H-2 class I antigens on murine tumour cell lines and normal cell populations.

T. Yoshida, I. Nakashima, F. Nagase, 1990, Immunology.

Allotype-linked immune response genes: roles in network control of the immune system.

T. Yoshida, I. Nakashima, T. Iwamoto, 1991, Experimental and clinical immunogenetics.

Augmented production of granulocyte-macrophage colony-stimulating factor and alpha/beta interferon in mice inoculated with heat-killed Corynebacterium liquefaciens

M. Ichihara, K. Shimokata, T. Yoshida, 1991, Infection and immunity.

Depression of afferent arc of the in vivo cytotoxic T-cell immunity by bacterial lipopolysaccharides.

K. Shimokata, T. Yoshida, I. Nakashima, 1985, Cellular immunology.

Promotion of cytotoxic T-cell generation in mixed leukocyte culture by phosphatidylinositol-specific phospholipase C from Bacillus thuringiensis

R. Taguchi, M. Kato, I. Nakashima, 1995, Infection and immunity.

Augmentation of antibody responses of mice to inhaled protein antigens by simultaneously inhaled bacterial lipopolysaccharides.

K. Shimokata, I. Nakashima, F. Nagase, 1986, Immunobiology.

Nonspecific crossreacting antigen (NCA) is a major member of the carcinoembryonic antigen (CEA)-related gene family expressed in lung cancer.

K. Isobe, K. Shimokata, I. Nakashima, 1993, British Journal of Cancer.

Structure of the murine Thy‐1 gene.

F. Grosveld, V. Giguère, K. Isobe, 1985, The EMBO journal.

Paradoxical effects of LPS on the T-cell-independent type 2 anti-H-2 alloantigen antibody responses to allogeneic erythrocytes.

K. Shimokata, I. Nakashima, F. Nagase, 1984, Transplantation.

Dynamics of generation of antigen loss variants from L1210 murine leukemia clones detected by a tumor-specific T-cell clone.

T. Yokochi, T. Yoshida, I. Nakashima, 1987, Cancer research.

The immunosuppressive effect of fresh allogeneic bone graft in mice

I. Nakashima, N. Ishiguro, H. Iwata, 1997, International Orthopaedics.

Characterization of the immunoregulatory action of saikosaponin-d.

M. Kato, I. Nakashima, T. Iwamoto, 1994, Cellular immunology.

Demonstration of lipid A‐binding proteins on murine lymphoma cells using R‐mutant Gram‐negative bacteria as a detector

T. Yokochi, T. Yoshida, R. Inagi, 1990, APMIS : acta pathologica, microbiologica, et immunologica Scandinavica.

The donor cell type controls anti-hapten (fluorescein isothiocyanate) primary antibody response to hapten-modified syngeneic cells.

I. Nakashima, F. Nagase, N. Kato, 1982, Immunology letters.

Transforming growth factor-beta 1 enhances the generation of allospecific cytotoxic T lymphocytes.

I. Nakashima, N. Ishiguro, K. Isobe, 1993, Immunology.

T cell maturation stage-linked heterogeneity of the glycosylphosphatidylinositol membrane anchor of Thy-1.

R. Taguchi, T. Yoshida, M. Kato, 1992, Immunobiology.

Ontogeny of the transplantation immunity of mice for rejecting ascitic allogeneic tumors.

I. Nakashima, F. Nagase, N. Kato, 1985, Developmental and comparative immunology.

Mode of alloantibody-mediated blockade of allo-sensitization for tumor allograft rejection.

K. Shimokata, T. Yoshida, I. Nakashima, 1989, Immunobiology.

Further characterization of the Sho-saio-to-mediated anti-tumor effect on melanoma developed in RET-transgenic mice.

M. Kato, I. Nakashima, K. Isobe, 2000, The Journal of investigative dermatology.

Dynamics of Cytotoxic T Lymphocyte Precursors in Vivo Assessed by Change in the Radiation Sensitivity

K. Shimokata, T. Yoshida, I. Nakashima, 1988, Scandinavian journal of immunology.

Direct activation of Sendai virus (HVJ)-specific cell-mediated immunity of mice for second set rejection of the virus-infected syngeneic tumor by noninfectious virus-sensitized spleen cells.

T. Yoshida, I. Nakashima, F. Nagase, 1985, Immunology letters.

Inhibitory effect of herpes simplex virus infection to target cells on recognition of minor histocompatibility antigens by cytotoxic T lymphocytes.

I. Nakashima, A. Takatsuki, T. Morishima, 1990, Journal of immunology.

Feedback suppression of staphylococcal enterotoxin-stimulated T-lymphocyte proliferation by macrophages through inductive nitric oxide synthesis

I. Nakashima, K. Isobe, Ken-ichi Isobe, 1992, Infection and immunity.

Intact and subcellular form of thymocytes of rats are exceptionally immunogenic in mice for inducing anti-Thy-1 T cell-independent class 2 antibody responses.

I. Nakashima, F. Nagase, P. Lake, 1983, Immunology letters.

Dissociated control by glycyrrhizin of proliferation and IL-2 production of murine thymocytes.

T. Yokochi, M. Kato, I. Nakashima, 1995, Cellular Immunology.

Establishment and characterisation of human carcinoembryonic antigen transgenic mice.

K. Shimokata, I. Nakashima, S. Oikawa, 1991, British Journal of Cancer.

Enhancement of nitric oxide production from activated macrophages by a purified form of ginsenoside (Rg1).

I. Nakashima, K. Kiuchi, K. Isobe, 1995, The American journal of Chinese medicine.

T cell independent Thy-1 allo-antibody response with the use of transgenic mice.

A. Kolstø, G. Kollias, F. Grosveld, 1986, Journal of immunology.

Development of host-dependent high-grade tumor-specific immunity through a novel mechanism triggered by the Lyt-2+ tumor-specific T cell clone (K7L) that induces temporal growth of L1210 leukemia-K7L-variant.

T. Yoshida, T. Iwamoto, F. Nagase, 1987, Journal of Immunology.

Simultaneous development of humoral and cellular tumor-specific immunity against L1210 mouse leukemia.

T. Yokochi, K. Yamada, I. Nakashima, 1985, Leukemia research.

Immune reactivity of allogeneically pregnant mice to paternal MHC antigens on fetal and placental cells assessed by second set rejection of ascites tumor cells.

I. Nakashima, F. Nagase, S. Goto, 1985, Journal of reproductive immunology.

Induction and characterization of minor histocompatibility antigens. Specific primary cytotoxic T lymphocyte responses in vitro.

T. Yoshida, I. Nakashima, T. Iwamoto, 1988, Journal of immunology.

Protein kinase C alpha-mediated chronic signal transduction for immunosenescence.

H. Hidaka, A. Akhand, M. Kato, 1997, Journal of Immunology.

Quantitative analysis of antigen for the induction of tolerance in carcinoembryonic antigen transgenic mice.

K. Shimokata, I. Nakashima, K. Isobe, 1992, Immunology.

Control of T-cell-dependent antibody responses of mice to rat antigens by donor cell types.

I. Nakashima, F. Nagase, N. Kato, 1983, Immunology letters.

Kupffer cells cytotoxicity against hepatoma cells is related to nitric oxide.

I. Nakashima, K. Aono, K. Isobe, 1994, Biochemical and biophysical research communications.

Differential display analysis of murine collagen‐induced arthritis: cloning of the cDNA‐encoding murine ATPase inhibitor

I. Nakashima, N. Ishiguro, H. Iwata, 1997, Immunology.

Determination of the molecular nature and cellular localization of Thy-1 in human renal tissue.

R. Taguchi, R. Dawson, R. Inagi, 1990, Immunology.