V. Fresquet

发表

High‐throughput sequencing analysis of the chromosome 7q32 deletion reveals IRF5 as a potential tumour suppressor in splenic marginal‐zone lymphoma

J. Martinez-Climent, E. Vizcarra, F. Prósper, 2012, British journal of haematology.

Integrative oncogenomic analysis of microarray data in hematologic malignancies.

J. Martinez-Climent, Á. Rubio, L. Fontán, 2010, Methods in molecular biology.

LMO2 expression reflects the different stages of blast maturation and genetic features in B-cell acute lymphoblastic leukemia and predicts clinical outcome

I. Lossos, E. Smeland, J. Martinez-Climent, 2011, Haematologica.

Localization of the site for the nucleotide effectors of Escherichia coli carbamoyl phosphate synthetase using site‐directed mutagenesis

V. Rubio, V. Fresquet, J. Cervera, 1999, FEBS letters.

Carbamate kinase from Enterococcus faecalis and Enterococcus faecium--cloning of the genes, studies on the enzyme expressed in Escherichia coli, and sequence similarity with N-acetyl-L-glutamate kinase.

V. Rubio, A. Marina, V. Fresquet, 1998, European journal of biochemistry.

Richter transformation driven by Epstein–Barr virus reactivation during therapy‐related immunosuppression in chronic lymphocytic leukaemia

Antonio Martínez, J. Martinez-Climent, F. Prósper, 2018, The Journal of pathology.

A cyclin-D1 interaction with BAX underlies its oncogenic role and potential as a therapeutic target in mantle cell lymphoma

I. Lossos, R. Siebert, J. Martinez-Climent, 2011, Proceedings of the National Academy of Sciences.

Epigenetic down-regulation of BIM expression is associated with reduced optimal responses to imatinib treatment in chronic myeloid leukaemia.

J. Martinez-Climent, F. Prósper, X. Agirre, 2009, European journal of cancer.

Partial randomization of the four sequential amidation reactions catalyzed by cobyric acid synthetase with a single point mutation.

F. Raushel, V. Fresquet, Lakenya Williams, 2007, Biochemistry.

Characterization and Expression of Multiple Alternatively Spliced Transcripts of the Goodpasture Antigen Gene Region

F. Revert, J. Penadés, J. Saus, 1995 .

Characterization and expression of multiple alternatively spliced transcripts of the Goodpasture antigen gene region. Goodpasture antibodies recognize recombinant proteins representing the autoantigen and one of its alternative forms.

F. Revert, J. Penadés, J. Saus, 1995, European journal of biochemistry.

Mechanism of cobyrinic acid a,c-diamide synthetase from Salmonella typhimurium LT2.

F. Raushel, V. Fresquet, Lakenya Williams, 2004, Biochemistry.

Homozygous deletions localize novel tumor suppressor genes in B-cell lymphomas.

Juan F. García, L. Staudt, A. Rosenwald, 2007, Blood.

Downregulation of FOXP1 is required during germinal center B-cell function.

O. Elemento, J. Martinez-Climent, Karen L. Bunting, 2013, Blood.

function Downregulation of FOXP1 is required during germinal center B-cell

O. Elemento, J. Martinez-Climent, Karen L. Bunting, 2013 .

Deep MRD profiling defines outcome and unveils different modes of treatment resistance in standard and high risk myeloma.

J. Martinez-Climent, A. Órfão, N. Puig, 2020, Blood.

Endogenous retroelement activation by epigenetic therapy reverses the Warburg effect and elicits mitochondrial-mediated cancer cell death.

M. Moreno-Aliaga, Jiahuai Han, J. Martinez-Climent, 2020, Cancer discovery.

chemoresistance in Burkitt lymphoma Reversion of epigenetically mediated BIM silencing overcomes

J. Hernández, M. Calasanz, J. Richter, 2014 .

Reversion of epigenetically mediated BIM silencing overcomes chemoresistance in Burkitt lymphoma.

J. Martinez-Climent, F. Prósper, J. Hernández, 2010, Blood.

Acquired mutations in BCL2 family proteins conferring resistance to the BH3 mimetic ABT-199 in lymphoma.

J. Martinez-Climent, V. Fresquet, C. Carolis, 2014, Blood.

Preclinical models for prediction of immunotherapy outcomes and immune evasion mechanisms in genetically heterogeneous multiple myeloma

J. San Miguel, J. Martinez-Climent, F. Prósper, 2023, Nature Medicine.

Understanding carbamoyl phosphate synthetase deficiency: impact of clinical mutations on enzyme functionality.

Javier Cervera, C. Marco-Marín, V. Rubio, 2005, Journal of molecular biology.

Site-directed mutagenesis of the regulatory domain of Escherichia coli carbamoyl phosphate synthetase identifies crucial residues for allosteric regulation and for transduction of the regulatory signals.

V. Rubio, S. Ramón-Maiques, V. Fresquet, 2000, Journal of molecular biology.

Mechanism of the reaction catalyzed by isoaspartyl dipeptidase from Escherichia coli.

Ricardo Martí-Arbona, F. Raushel, J. Thoden, 2005, Biochemistry.

Photoaffinity labeling with the activator IMP and site-directed mutagenesis of histidine 995 of carbamoyl phosphate synthetase from Escherichia coli demonstrate that the binding site for IMP overlaps with that for the inhibitor UMP.

V. Rubio, C. J. Lusty, A. Marina, 1999, Biochemistry.

Kinetic mechanism of asparagine synthetase from Vibrio cholerae.

F. Raushel, J. Thoden, H. Holden, 2004, Bioorganic chemistry.

Activation of the PP2A-B56α heterocomplex synergizes with venetoclax therapies in AML through BCL2 and MCL1 modulation.

J. Martinez-Climent, M. Odero, G. Narla, 2022, Blood.

The multiple amidation reactions catalyzed by Cobyric acid synthetase from Salmonella typhimurium are sequential and dissociative.

F. Raushel, P. J. Santander, V. Fresquet, 2007, Journal of the American Chemical Society.

Reversion of epigenetically mediated BIM silencing overcomes chemoresistance in Burkitt lymphoma.

J. Martinez-Climent, F. Prósper, M. Calasanz, 2010, Blood.

LMO2 expression reflects the different stages of blast maturation and genetic features in B-cell acute lymphoblastic leukemia and predicts clinical outcome

I. Lossos, E. Smeland, J. Martinez-Climent, 2011, Haematologica.

Mechanism of allosteric modulation of Escherichia coli carbamoyl phosphate synthetase probed by site‐directed mutagenesis of ornithine site residues

V. Rubio, V. Fresquet, J. Cervera, 2002, FEBS letters.