J. Cobb

发表

Double functions for the Mre11 complex during DNA double-strand break repair and replication.

V. Borde, J. Cobb, 2009, The international journal of biochemistry & cell biology.

The non-homologous end-joining factor Nej1 inhibits resection mediated by Dna2–Sgs1 nuclease-helicase at DNA double strand breaks

S. Lees-Miller, Brandi L. Mahaney, J. Cobb, 2017, The Journal of Biological Chemistry.

Cohesin association to replication sites depends on rad50 and promotes fork restart.

M. Davidson, J. Petrini, A. Lengronne, 2012, Molecular cell.

A Role for the Mre11-Rad50-Xrs2 Complex in Gene Expression and Chromosome Organization.

M. Rowicka, M. Skrzypczak, K. Ginalski, 2020, Molecular cell.

Smc5/6 in the rDNA modulates lifespan independently of Fob1

A. Mojumdar, Megan E. Chan, T. Harkness, 2021, Aging cell.

A Fob1 independent role for the Smc5/6 complex in the rDNA that modulates lifespan

A. Mojumdar, Megan E. Chan, T. Harkness, 2020, bioRxiv.

A high-throughput alpha particle irradiation system for monitoring DNA damage repair, genome instability and screening in human cell and yeast model systems

D. Brenner, N. Ploquin, A. A. Goodarzi, 2020, Nucleic acids research.

SURVEY AND SUMMARY RecQ helicases: lessons from model organisms

Lotte Bjergbaek, J. Cobb, 2006 .

Structural Requirements for N-Trimethylation of Lysine 115 of Calmodulin*

D. M. Roberts, J. Cobb, 2000, The Journal of Biological Chemistry.

SIR telomere silencing depends on nuclear envelope lipids and modulates sensitivity to a lysolipid drug

V. Zaremberg, J. Cobb, Sarah Moradi-Fard, 2022, bioRxiv.

The C-terminus of Nej1 is critical for nuclear localization and non-homologous end-joining.

S. Lees-Miller, Brandi L. Mahaney, J. Cobb, 2014, DNA repair.

SIR telomere silencing depends on nuclear envelope lipids and modulates sensitivity to a lysolipid drug

V. Zaremberg, J. Cobb, Sarah Moradi-Fard, 2022, bioRxiv.

Nej1 Interacts with Mre11 to Regulate Tethering and Dna2 Binding at DNA Double-Strand Breaks

K. Dubrana, S. Lees-Miller, J. Petrini, 2019, Cell reports.

Modeling cancer genomic data in yeast reveals selection against ATM function during tumorigenesis

B. Taylor, D. Patel, Matthew T. Chang, 2019, bioRxiv.

Pathogenic, but not non-pathogenic, Rickettsia manipulate inflammasome-dependent IL-1 responses to facilitate their replication and host dissemination

A. Azad, O. Voss, L. Detolla, 2021 .

The MRX complex stabilizes the replisome independently of the S phase checkpoint during replication stress

P. Pasero, C. Alabert, J. Cobb, 2009, The EMBO journal.

Replisome instability, fork collapse, and gross chromosomal rearrangements arise synergistically from Mec1 kinase and RecQ helicase mutations.

S. Gasser, Thomas Schleker, Lotte Bjergbaek, 2005, Genes & development.

PolySUMOylation by Siz2 and Mms21 triggers relocation of DNA breaks to nuclear pores through the Slx5/Slx8 STUbL

Monika Tsai-Pflugfelder, S. Gasser, N. Delgoshaie, 2016, Genes & development.

DNA polymerase stabilization at stalled replication forks requires Mec1 and the RecQ helicase Sgs1

S. Gasser, Kenji Shimada, Lotte Bjergbaek, 2003, The EMBO journal.

Smc5/6 Is a Telomere-Associated Complex that Regulates Sir4 Binding and TPE

P. Chartrand, E. Cusanelli, J. Cobb, 2016, PLoS genetics.

SIR telomere silencing depends on nuclear envelope lipids and modulates sensitivity to a lysolipid

V. Zaremberg, J. Cobb, Sarah Moradi-Fard, 2023, bioRxiv.

During Replication Stress, Non-Smc Element 5 (Nse5) Is Required for Smc5/6 Protein Complex Functionality at Stalled Forks*

K. Shirahige, D. Branzei, Demis Menolfi, 2012, The Journal of Biological Chemistry.

RecQ helicases and genome stability: lessons from model organisms and human disease.

S. Gasser, Lotte Bjergbaek, J. Cobb, 2002, Swiss medical weekly.

Phosphorylation of Soybean Nodulin 26 on Serine 262 Enhances Water Permeability and Is Regulated Developmentally and by Osmotic Signals Article, publication date, and citation information can be found at www.plantcell.org/cgi/doi/10.1105/tpc.009787.

I. Wallace, D. M. Roberts, J. Cobb, 2003, The Plant Cell Online.

A decade of understanding spatio-temporal regulation of DNA repair by the nuclear architecture.

J. Cobb, H. Saad, Hicham Saad, 2016, Biochemistry and cell biology = Biochimie et biologie cellulaire.

Changes in DNA double-strand break repair during aging correlate with an increase in genomic mutations.

A. Mojumdar, J. Cobb, Nancy Adam, 2022, Journal of molecular biology.

Changes in DNA double-strand break repair during aging correlate with an increase in genomic mutations

A. Mojumdar, J. Cobb, Nancy Adam, 2022, bioRxiv.

Chromatin Modifications in DNA Repair and Cancer

K. Riabowol, M. Renaud-Young, J. Cobb, 2016 .

Redundancy, insult-specific sensors and thresholds: unlocking the S-phase checkpoint response.

S. Gasser, Kenji Shimada, Susan M Gasser, 2004, Current opinion in genetics & development.

Mechanistically distinct roles for Sgs1p in checkpoint activation and replication fork maintenance

S. Gasser, Lotte Bjergbaek, J. Cobb, 2005, The EMBO journal.

The yeast Shu complex couples error‐free post‐replication repair to homologous recombination

W. Xiao, Charles Boone, Ke Zhang, 2009, Molecular microbiology.

Mapping genomic targets of DNA helicases by chromatin immunoprecipitation in Saccharomyces cerevisiae.

H. van Attikum, J. Cobb, 2010, Methods in molecular biology.

SUNny Ways: The Role of the SUN-Domain Protein Mps3 Bridging Yeast Nuclear Organization and Lipid Homeostasis

V. Zaremberg, J. Cobb, Sarah Moradi-Fard, 2020, Frontiers in Genetics.

Non-Smc element 5 (Nse5) of the Smc5/6 complex interacts with SUMO pathway components

J. Cobb, Lindsay G. Ball, Denise E. Bustard, 2016, Biology Open.

RecQ helicases: multiple roles in genome maintenance.

S. Gasser, I. Hickson, Lotte Bjergbaek, 2003, Trends in cell biology.

RecQ helicases: at the heart of genetic stability

S. Gasser, Lotte Bjergbaek, J. Cobb, 2002, FEBS letters.

RecQ helicases: lessons from model organisms

Lotte Bjergbaek, J. Cobb, 2006, Nucleic acids research.

The Mre11-Rad50-Xrs2 Complex Is Required for Yeast DNA Postreplication Repair

W. Xiao, B. Ziola, M. Hanna, 2014, PloS one.

Multifunctional properties of Nej1XLF C-terminus promote end-joining and impact DNA double-strand break repair pathway choice.

A. Mojumdar, J. Cobb, Nancy Adam, 2022, DNA repair.

Multifunctional properties of Nej1XLF C-terminus promote end-joining and impact DNA double-strand break repair pathway choice

A. Mojumdar, J. Cobb, Nancy Adam, 2022, bioRxiv.

The NuA4 Complex Promotes Translesion Synthesis (TLS)-Mediated DNA Damage Tolerance

G. Chua, M. Renaud-Young, K. Chatfield-Reed, 2015, Genetics.

Nej1 interacts with Sae2 at DNA double-stranded breaks to inhibit DNA resection

A. Mojumdar, J. Cobb, Nancy Adam, 2022, The Journal of biological chemistry.

Nej1XLF interacts with Sae2CTIP to inhibit Dna2 mediated resection at DNA double strand break

A. Mojumdar, J. Cobb, Nancy Adam, 2021, bioRxiv.

Nej1 Interacts with Mre11 to Regulate Tethering and Dna2 Binding at DNA Double-Strand Breaks

K. Dubrana, S. Lees-Miller, J. Petrini, 2019, Cell reports.

Sgs1 BLM independent role of Dna2 DNA2 nuclease at DNA double strand break is inhibited by Nej1 XLF

A. Mojumdar, J. Cobb, Nancy Adam, 2021 .

mediated resection at DNA double strand breaks

A. Mojumdar, J. Cobb, Nancy Adam, 2021 .

Structural elements within the methylation loop (residues 112-117) and EF hands III and IV of calmodulin are required for Lys(115) trimethylation.

C. Han, D. M. Wills, D. M. Roberts, 1999, The Biochemical journal.

Changes in DNA double-strand break repair during aging correlate with an increase in genomic mutations

A. Mojumdar, J. Cobb, Nancy Adam, 2022, bioRxiv.

Smc5/6 Is a Telomere-Associated Complex that Regulates Sir4 Binding and TPE

P. Chartrand, E. Cusanelli, J. Cobb, 2016, PLoS genetics.