E. Mberu

发表

Variability in the metabolism of proguanil to the active metabolite cycloguanil in healthy Kenyan adults.

A. Breckenridge, S. Ward, C. Nevill, 1990, Transactions of the Royal Society of Tropical Medicine and Hygiene.

Inter-individual variation in the metabolic activation of the antimalarial biguanides.

S. Ward, N. Helsby, W. Watkins, 1991, Parasitology today.

The efficacy of antifolate antimalarial combinations in Africa: a predictive model based on pharmacodynamic and pharmacokinetic analyses.

C. Plowe, W. Watkins, W M Watkins, 1997, Parasitology today.

The disposition of intramuscular artemether in children with cerebral malaria; a preliminary study.

B. Lowe, K. Marsh, M. English, 1997, Transactions of the Royal Society of Tropical Medicine and Hygiene.

Genetic diversity of Plasmodium falciparum parasites from Kenya is not affected by antifolate drug selection.

E. Nduati, A. Nzila, A. Ross, 2002, International journal for parasitology.

Cutaneous hypersensitivity reactions to thiacetazone, HIV infection and thiacetazone concentrations in plasma.

C. Gilks, W. Watkins, P. Nunn, 1996, British journal of clinical pharmacology.

Ferriprotoporphyrin catalysed decomposition of artemether: analytical and pharmacological implications.

S. Ward, G. Edwards, W. Watkins, 1994, Biochemical pharmacology.

Antimalarial benzo[c]phenanthridines.

S. Mackay, W. Watkins, R. Waigh, 2005, Bioorganic & medicinal chemistry letters.

A new antiplasmodial coumarin from Toddalia asiatica roots.

H. Oketch-Rabah, E. Mberu, J. Lisgarten, 2000, Fitoterapia.

In Vitro Activities of 2,4-Diaminoquinazoline and 2,4-Diaminopteridine Derivatives against Plasmodium falciparum

Kevin Marsh, E. Nduati, A. Nzila, 2004, Antimicrobial Agents and Chemotherapy.

Antimalarial activity in crude extracts of Malawian medicinal plants.

W. Watkins, E. Mberu, E. Fabiano, 1996, Annals of tropical medicine and parasitology.

Antimalarial Activity of Some Kenyan Medicinal Plants

S. F. Dossaji, H. Oketch-Rabah, E. Mberu, 1999 .

Potent antimalarial activity of the alkaloid nitidine, isolated from a Kenyan herbal remedy

S. F. Dossaji, W. Watkins, P. Waterman, 1995, Antimicrobial agents and chemotherapy.

More on 'the efficacy of antifolate antimalarial combinations in Africa'.

C. Plowe, W. Watkins, P. Winstanley, 1999, Parasitology today.

Differential extraction of artemether and its metabolite dihydroartemisinin from plasma and determination by high-performance liquid chromatography.

W. Watkins, E. Mberu, D. Muhia, 1994, Journal of chromatography. B, Biomedical applications.

Measurement of physiological concentrations of dapsone and its monoacetyl metabolite: a miniaturised assay for liquid or filter paper-absorbed samples.

W. Watkins, E. Mberu, D. Muhia, 1996, Journal of chromatography. B, Biomedical applications.

The changing in vitro susceptibility pattern to pyrimethamine/sulfadoxine in Plasmodium falciparum field isolates from Kilifi, Kenya.

A. Nzila, G. Kokwaro, W. Watkins, 2000, The American journal of tropical medicine and hygiene.

Chemosensitization of Plasmodium falciparum by Probenecid In Vitro

A. Nzila, K. Marsh, G. Kokwaro, 2003, Antimicrobial Agents and Chemotherapy.

Molecular evidence of greater selective pressure for drug resistance exerted by the long-acting antifolate Pyrimethamine/Sulfadoxine compared with the shorter-acting chlorproguanil/dapsone on Kenyan Plasmodium falciparum.

E. Nduati, A. Nzila, S. Monks, 2000, The Journal of infectious diseases.

Towards an Understanding of the Mechanism of Pyrimethamine-Sulfadoxine Resistance in Plasmodium falciparum: Genotyping of Dihydrofolate Reductase and Dihydropteroate Synthase of Kenyan Parasites

A. Nzila, W. Watkins, C. Sibley, 2000, Antimicrobial Agents and Chemotherapy.

Pyrimethamine-sulfadoxine resistance in Plasmodium falciparum: what next?

J. E. Hyde, J. Kublin, A. Cowman, 2001, Trends in parasitology.

Chlorproguanil-dapsone for treatment of drug-resistant falciparum malaria in Tanzania

E. Nduati, A. Nzila, T. Mutabingwa, 2001, The Lancet.

The disposition of oral and intramuscular pyrimethamine/sulphadoxine in Kenyan children with high parasitaemia but clinically non-severe falciparum malaria.

K. Marsh, D. Warrell, C. Newton, 1992, British journal of clinical pharmacology.

Inter-subject variability in the metabolism of proguanil to the active metabolite cycloguanil in man.

A. Breckenridge, S. Ward, H. Gilles, 1989, British journal of clinical pharmacology.

Towards optimal regimens of parenteral quinine for young African children with cerebral malaria: the importance of unbound quinine concentration.

D. Warrell, S. Ward, W. Watkins, 1993, Transactions of the Royal Society of Tropical Medicine and Hygiene.

Sulfa drugs strike more than once.

A. Nzila, I. Macreadie, O. Patel, 2004, Trends in parasitology.

Kenyan Plasmodium falciparum Field Isolates: Correlation between Pyrimethamine and Chlorcycloguanil Activity In Vitro and Point Mutations in the Dihydrofolate Reductase Domain

C. Plowe, W. Watkins, C. Sibley, 1998, Antimicrobial Agents and Chemotherapy.

Towards optimal regimens of parenteral quinine for young African children with cerebral malaria: unbound quinine concentrations following a simple loading dose regimen.

B. Lowe, K. Marsh, W. Watkins, 1994, Transactions of the Royal Society of Tropical Medicine and Hygiene.

Prophylactic phenobarbitone in young children with severe falciparum malaria: pharmacokinetics and clinical effects.

F. Kirkham, K. Marsh, N. Peshu, 1992, British journal of clinical pharmacology.

Measurement of quinine in filter paper-absorbed blood by high-performance liquid chromatography.

S. Ward, W. Watkins, P. Winstanley, 1991, Journal of chromatography.

The effect of quinine on the electroretinograms of children with pediatric cerebral malaria.

S. Harding, M. Molyneux, T. Taylor, 2003, The Journal of infectious diseases.

Halofantrine pharmacokinetics in Kenyan children with non-severe and severe malaria.

K. Marsh, G. Kokwaro, W. Watkins, 1995, British journal of clinical pharmacology.

A single dose of intramuscular sulfadoxine-pyrimethamine as an adjunct to quinine in the treatment of severe malaria: pharmacokinetics and efficacy.

K. Marsh, C. Newton, C. Nevill, 1993, Transactions of the Royal Society of Tropical Medicine and Hygiene.

Measurement of halofantrine and its major metabolite desbutylhalofantrine in plasma and blood by high-performance liquid chromatography: a new methodology.

W. Watkins, E. Mberu, D. Muhia, 1992, Journal of chromatography.

The antimalarial triazine WR99210 and the prodrug PS-15: folate reversal of in vitro activity against Plasmodium falciparum and a non-antifolate mode of action of the prodrug.

W. Watkins, P. Winstanley, D. Jacobus, 1999, The American journal of tropical medicine and hygiene.

In vitro activities of novel antifolate drug combinations against Plasmodium falciparum and human granulocyte CFUs

A. Breckenridge, W. Watkins, P. Winstanley, 1995, Antimicrobial agents and chemotherapy.

Plasmodium falciparum: in vitro activity of sulfadoxine and dapsone in field isolates from Kenya: point mutations in dihydropteroate synthase may not be the only determinants in sulfa resistance.

E. Nduati, A. Nzila, A. Ross, 2002, Experimental parasitology.