Y. Mérand

发表

Synthesis and biological activities of thioether derivatives related to the antiestrogens tamoxifen and ICI 164384

D. Poirier, F. Labrie, S. Auger, 1995, The Journal of Steroid Biochemistry and Molecular Biology.

Derivatives of ethynylestradiol with oxygenated 17 alpha-alkyl side chain: synthesis and biological activity.

C. Labrie, D. Poirier, F. Labrie, 1990, Journal of steroid biochemistry.

P. Savard, F. Labrie, A. Dupont, 1981, Life sciences.

Synthesis and in vitro antiandrogenic activity of 17β-hydroxy-17α-(ω-hydroxy/haloalkyn-1′-yl)-4-methyl-4-aza-3-oxo-5α-androstan-(1-ene)-3-ones

F. Labrie, Y. Mérand, Xun Li, 1995 .

Differential distribution of β-endorphin and enkephalins in rat and bovine brain

H. Vaudry, N. Barden, A. Dupont, 1980, Regulatory Peptides.

Regulation of progesterone-binding breast cyst protein GCDFP-24 secretion by estrogens and androgens in human breast cancer cells: a new marker of steroid action in breast cancer.

J. Simard, F. Labrie, D. Haagensen, 1990, Endocrinology.

Relationship of Opiate Peptides to Neuroendocrine Functions

H. Vaudry, N. Barden, A. Lemay, 1982 .

Effect of propylthiouracil and thyroxine on the inactivation of somatostatin by rat hypothalamus.

N. Barden, A. Dupont, Y. Mérand, 1978, Life sciences.

Long‐term inhibitory effects of a novel anti‐estrogen on the growth of ZR‐75‐1 and MCF‐7 human breast cancer tumors in nude mice

C. Labrie, F. Labrie, C. Martel, 1997, International journal of cancer.

Additive inhibitory effects of an androgen and the antiestrogen EM-170 on estradiol-stimulated growth of human ZR-75-1 breast tumors in athymic mice.

F. Labrie, Y. Mérand, C. Geng, 1991, Cancer research.

Regional distributions of somatostatin and cholecystokinin-like immunoreactivities in rat and bovine brain

G. Dockray, N. Barden, A. Dupont, 1981, Peptides.

Antiestrogenic properties of keoxifene,trans-4-hydroxytamoxifen, and ICI 164384, a new steroidal antiestrogen, in ZR-75-1 human breast cancer cells

D. Poirier, F. Labrie, Y. Mérand, 1989, Breast Cancer Research and Treatment.

Characterization of the effects of the novel non‐steroidal antiestrogen EM‐800 on basal and estrogen‐induced proliferation of T‐47D, ZR‐75‐1 and MCF‐7 human breast cancer cells in vitro

J. Simard, C. Labrie, F. Labrie, 1997, International journal of cancer.

Effect of twenty-four-week treatment with the antiestrogen EM-800 on estrogen-sensitive parameters in intact and ovariectomized mice.

C. Labrie, F. Labrie, A. Bélanger, 1998, Endocrinology.

Binding characteristics of novel nonsteroidal antiestrogens to the rat uterine estrogen receptors

F. Labrie, C. Martel, L. Provencher, 1998, The Journal of Steroid Biochemistry and Molecular Biology.

Printed in U.S.A. Copyright © 1998 by The Endocrine Society Comparison of the Effects of the New Orally Active Antiestrogen EM-800 with ICI 182 780 and Toremifene on Estrogen-Sensitive Parameters in the Ovariectomized Mouse

C. Labrie, F. Labrie, C. Martel, 2022 .

Comparative effects of 28‐day treatment with the new anti‐estrogen EM‐800 and tamoxifen on estrogen‐sensitive parameters in intact mice

C. Labrie, F. Labrie, C. Martel, 1997, International journal of cancer.

Limitation of access to highly palatable foods increases the norepinephrine content of many discrete hypothalamic and amygdaloidal nuclei of rat brain.

P. Savard, A. Dupont, Y. Mérand, 1983, Life sciences.

Serotonin, 5-hydroxyindoleacetic acid and substance P content of discrete brain nuclei in rats made hypo- or hyperthyroid in the neonatal period: effect of growth hormone treatment.

P. Savard, A. Dupont, Y. Mérand, 1984, Brain research.

Influences of both thyroid and bovine growth hormones on substance P, thyrotropin-releasing hormone, serotonin and 5-hydroxyindoleacetic acid contents in the lumbar spinal cord of developing rats.

P. Savard, P. Bédard, J. Dussault, 1984, Brain research.

Effect of neonatal thyroid deficiency on the catecholamine, substance P, and thyrotropin-releasing hormone contents of discrete rat brain nuclei.

N. Barden, B. Gagné, J. Dussault, 1981, Endocrinology.

3H-mepyramine binding in various regions of rat brain following chronic treatment with different classes of antidepressant drugs

P. Savard, A. Dupont, Y. Mérand, 1982, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

Effects of the aromatase inhibitor 4-hydroxyandrostenedione and the antiandrogen flutamide on growth and steroid levels in DMBA-induced rat mammary tumors

B. Marchetti, F. Labrie, A. Bélanger, 1988, Breast Cancer Research and Treatment.

Changes in the β-endorphin content of discrete hypothalamic nuclei during the estrous cycle of the rat

M. Garon, N. Barden, A. Dupont, 1981, Brain Research.

Interactions between Estrogens, Androgens, Progestins, and Glucocorticoids in ZR‐75‐1 Human Breast Cancer Cells

M. Dumont, J. Simard, C. Labrie, 1990, Annals of the New York Academy of Sciences.

beta-Endorphin and met-enkephalins: their distribution, modulation by estrogens and haloperidol, and role in neuroendocrine control.

H. Vaudry, F. Labrie, N. Barden, 1980, Federation proceedings.

Blockade of the stimulatory effect of estrogens, OH-tamoxifen, OH-toremifene, droloxifene, and raloxifene on alkaline phosphatase activity by the antiestrogen EM-800 in human endometrial adenocarcinoma Ishikawa cells.

J. Simard, C. Labrie, D. Poirier, 1997, Cancer research.

Pure Antagonistic Effect of a New Steroidal Antiestrogen in Rat Anterior Pituitary Cells in Culture and in Mouse Uterus

J. Simard, C. Labrie, F. Labrie, 1990 .

EM-652 (SCH 57068), a third generation SERM acting as pure antiestrogen in the mammary gland and endometrium

Virgile Richard, J. Simard, V. Giguère, 1999, The Journal of Steroid Biochemistry and Molecular Biology.

(S)-(+)-4-[7-(2,2-dimethyl-1-oxopropoxy)-4-methyl-2-[4-[2-(1-piperidinyl)-ethoxy]phenyl]-2H-1-benzopyran-3-yl]-phenyl 2,2-dimethylpropanoate (EM-800): a highly potent, specific, and orally active nonsteroidal antiestrogen.

J. Simard, C. Labrie, J. Mailhot, 1997, Journal of medicinal chemistry.

Effect of neonatal hypothyroidism on the serotonin system of the rat brain

P. Savard, T. Paolo, A. Dupont, 1984, Brain Research.

Favorskii rearrangements of .alpha.-halogenated acetylcycloalkanes. 3

Y. Mérand, C. Engel, J. Côté, 1982 .

Growth inhibition of 7,12-dimethylbenz(a)anthracene-induced rat mammary tumors by controlled-release low-dose medroxyprogesterone acetate

M. Lepage, F. Labrie, A. Bélanger, 2005, Breast Cancer Research and Treatment.

Effects of thyroid state on serotonin, 5-hydroxyindoleacetic acid and substance P contents in discrete brain nuclei of adult rats

P. Savard, T. Paolo, A. Dupont, 1983, Neuroscience.

Age-dependent changes in the beta-endorphin content of discrete rat brain nuclei.

H. Vaudry, F. Labrie, N. Barden, 1981, Brain research.

Comparative effects of neonatal hypothyroidism and euthyroidism on TRH and substance P content of lumbar spinal cord in saline and PCPA-treated rats

P. Savard, P. Bédard, J. Dussault, 1983, Brain Research.

Synthesis of 17β-estradiol derivatives with n-butyl, n-methyl alkylamide side chain at position 15

D. Poirier, F. Labrie, Y. Mérand, 1991 .

Inhibitory effect of a steroidal antiestrogen (EM-170) on estrone-stimulated growth of 7,12-dimethylbenz(a)anthracene (DMBA)-induced mammary carcinoma in the rat

C. Labrie, F. Labrie, Y. Mérand, 1995, Breast Cancer Research and Treatment.

Controlled release low dose medroxyprogesterone acetate (MPA) inhibits the development of mammary tumors induced by dimethyl-benz(a) anthracene in the rat

M. Lepage, F. Labrie, A. Bélanger, 2004, Breast Cancer Research and Treatment.

Pure selective estrogen receptor modulators, new molecules having absolute cell specificity ranging from pure antiestrogenic to complete estrogen-like activities.

J. Simard, V. Giguère, C. Labrie, 2001, Advances in protein chemistry.

Synthesis and biological activity of new halo-steroidal antiestrogens.

C. Labrie, F. Labrie, Y. Mérand, 1991, Journal of medicinal chemistry.

Synthesis and structure–activity relationships of analogs of EM-652 (acolbifene), a pure selective estrogen receptor modulator. Study of nitrogen substitution

J. Simard, J. Mailhot, F. Labrie, 2005, Journal of enzyme inhibition and medicinal chemistry.

RAPID INACTIVATION OF ENKEPHALIN-LIKE MATERIAL BY C.S.F. IN CHRONIC SCHIZOPHRENIA

J. Bouchard, F. Labrie, Y. Mérand, 1978, The Lancet.

Enzymic inactivation of neurotensin by hypothalamic and brain extracts of the rat.

A. Dupont, Y. Mérand, 1978, Life sciences.

Novel compounds inhibit estrogen formation and action.

C. Labrie, F. Labrie, C. Martel, 1992, Cancer research.

Extensive esterification of adrenal C19-delta 5-sex steroids to long-chain fatty acids in the ZR-75-1 human breast cancer cell line.

D. Poirier, F. Labrie, A. Bélanger, 1989, The Journal of biological chemistry.

Long‐term inhibitory effect of the orally active and pure antiestrogen EM‐800 on the growth of human breast cancer xenografts in nude mice

C. Labrie, F. Labrie, S. Gauthier, 2000, International journal of cancer.

Validated high-performance liquid chromatographic methods for quantitation of a novel nonsteroidal antiestrogen.

F. Labrie, A. Coquet, Y. Mérand, 1998, Journal of chromatography. A.

Comparative effects of 28‐day treatment with the new anti‐estrogen EM‐800 and tamoxifen on estrogen‐sensitive parameters in intact mice

C. Labrie, F. Labrie, C. Martel, 1997, International journal of cancer.

Synthesis and antiestrogenic activity of diaryl thioether derivatives.

J. Simard, D. Poirier, F. Labrie, 1994, Journal of medicinal chemistry.