P. Scullion

发表

Metabolomic profiling of biomarkers of liver X receptor-induced toxicity in mouse liver tissue

L. MacIntyre, D. Watson, Liang Zheng, 2011, Metabolomics.

6-Phenyl-1H-imidazo[4,5-c]pyridine-4-carbonitrile as cathepsin S inhibitors.

Joost C. M. Uitdehaag, X. Fradera, Z. Rankovic, 2010, Bioorganic & medicinal chemistry letters.

Host-parasite co-metabolic activation of antitrypanosomal aminomethyl-benzoxaboroles

Mark C. Field, Isabel M. Vincent, K. Read, 2018, PLoS pathogens.

Discovery of super soft-drug modulators of sphingosine-1-phosphate receptor 1

K. Read, P. Wyatt, W. McLean, 2018, Bioorganic & medicinal chemistry letters.

Discovery and Optimization of 5-Amino-1,2,3-triazole-4-carboxamide Series against Trypanosoma

A. Hill, Frederick R. C. Simeons, L. Stojanovski, 2017 .

Use of a solvent-free dry matrix coating for quantitative matrix-assisted laser desorption ionization imaging of 4-bromophenyl-1,4-diazabicyclo(3.2.2)nonane-4-carboxylate in rat brain and quantitative analysis of the drug from laser microdissected tissue regions.

A. Pitt, L. MacIntyre, D. Watson, 2010, Analytical chemistry.

Design and optimization of a series of novel 2-cyano-pyrimidines as cathepsin K inhibitors.

X. Fradera, Z. Rankovic, J. Uitdehaag, 2010, Bioorganic & medicinal chemistry letters.

Discovery of pro-soft drug modulators of sphingosine-1-phosphate receptor 1 (S1PR1)

K. Read, P. Wyatt, W. McLean, 2020 .

Identification and development of a series of disubstituted piperazines for the treatment of Chagas disease.

Peter G. Dodd, Frederick R. C. Simeons, L. Stojanovski, 2022, European journal of medicinal chemistry.

Cycling and walking: Why don't hospitals provide facilities for healthy transport?

H. Owen, P. Scullion, Rosalie H. Day, 1999 .

Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis

Juan A. Bueren-Calabuig, Andrei V. Pisliakov, David W. Gray, 2019, Proceedings of the National Academy of Sciences.

Chemical synthesis, characterisation and in vitro and in vivo metabolism of the synthetic opioid MT-45 and its newly identified fluorinated analogue 2F-MT-45 with metabolite confirmation in urine samples from known drug users

K. Read, N. Nic Daéid, O. Sutcliffe, 2018, Forensic Toxicology.

A role for trypanosomatid aldo-keto reductases in methylglyoxal, prostaglandin and isoprostane metabolism

S. Norval, A. Fairlamb, J. Dunne, 2018, The Biochemical journal.

Identification of Morpholino Thiophenes as Novel Mycobacterium tuberculosis Inhibitors, Targeting QcrB

A. Korkegian, K. Read, P. Hipskind, 2018, Journal of medicinal chemistry.

Discovery and Optimization of 5-Amino-1,2,3-triazole-4-carboxamide Series against Trypanosoma cruzi

A. Hill, Frederick R. C. Simeons, L. Stojanovski, 2017, Journal of medicinal chemistry.

Liquid chromatography/mass spectrometric bioanalysis of a modified gamma-cyclodextrin (Org 25969) and Rocuronium bromide (Org 9426) in guinea pig plasma and urine: its application to determine the plasma pharmacokinetics of Org 25969.

P. Desmond, P. Scullion, I. Mayer, 2002, Rapid communications in mass spectrometry : RCM.

A Proteomic Approach to Analyze the Aspirin-mediated Lysine Acetylome*

M. Tatham, C. Cole, R. Hay, 2016, Molecular & Cellular Proteomics.

Spirocycle MmpL3 Inhibitors with Improved hERG and Cytotoxicity Profiles as Inhibitors of Mycobacterium tuberculosis Growth

A. Korkegian, L. Stojanovski, K. Read, 2021, ACS omega.

Lead Optimization of a Pyrazole Sulfonamide Series of Trypanosoma bruceiN-Myristoyltransferase Inhibitors: Identification and Evaluation of CNS Penetrant Compounds as Potential Treatments for Stage 2 Human African Trypanosomiasis

Stuart P. McElroy, S. Norval, Frederick R. C. Simeons, 2014, Journal of medicinal chemistry.

Development of a Novel Lead that Targets M. tuberculosis Polyketide Synthase 13

Lisa K. Woolhiser, S. Norval, J. Sacchettini, 2017, Cell.

2-Phenyl-9H-purine-6-carbonitrile derivatives as selective cathepsin S inhibitors.

X. Fradera, Z. Rankovic, J. Uitdehaag, 2010, Bioorganic & medicinal chemistry letters.

2-Mercapto-Quinazolinones as Inhibitors of Type II NADH Dehydrogenase and Mycobacterium tuberculosis: Structure–Activity Relationships, Mechanism of Action and Absorption, Distribution, Metabolism, and Excretion Characterization

K. Read, K. Chibale, T. Ioerger, 2018, ACS infectious diseases.

Rapid thermal processing of sendust for magnetic recording applications

D. Macken, P. Scullion, Kevin J. Duddy, 2000 .

Analysis of changes in triacylglycerol ratios in mouse liver and plasma in response to a liver X receptor agonist

L. MacIntyre, P. Scullion, H. McKinnon, 2011, Metabolomics.

Molecular basis of RNA guanine-7 methyltransferase (RNMT) activation by RAM

Juan A. Bueren-Calabuig, Andrei V. Pisliakov, V. Cowling, 2016, Nucleic acids research.

Optimization of TAM16, a Benzofuran That Inhibits the Thioesterase Activity of Pks13; Evaluation toward a Preclinical Candidate for a Novel Antituberculosis Clinical Target

Robert H Bates, L. Stojanovski, K. Read, 2021, Journal of medicinal chemistry.

Analysis of changes in triacylglycerol ratios in mouse liver and plasma in response to a liver X receptor agonist

L. MacIntyre, D. Watson, P. Scullion, 2012, Metabolomics.

Injury risk to specific body regions of pedestrians in frontal vehicle crashes modeled by empirical, in-depth accident data.

Paul Scullion, Randa Radwan Samaha, Thomas Helmer, 2010, Stapp car crash journal.

Lead optimization of a pyrazole sulfonamide series of trypanosoma brucei N myristoyltransferase inhibitors

Stuart P. McElroy, S. Norval, Frederick R. C. Simeons, 2014 .

Discovery of Soft-Drug Topical Tool Modulators of Sphingosine-1-phosphate Receptor 1 (S1PR1)

K. Read, P. Wyatt, W. McLean, 2019, ACS medicinal chemistry letters.

Paul Scullion, Richard M Morgan, Kennerly Digges, 2008, Annals of advances in automotive medicine. Association for the Advancement of Automotive Medicine. Annual Scientific Conference.

Predicting the Injury Severity of Pedestrians in Frontal Vehicle Crashes based on Empirical, In-depth Accident Data

Paul Scullion, Randa Radwan Samaha, Thomas Helmer, 2011, Int. J. Intell. Transp. Syst. Res..

Kinematical, physiological, and vehicle-related influences on pedestrian injury severity in frontal vehicle crashes: Multivariate analysis and cross-validation

Paul Scullion, Randa Radwan Samaha, Thomas Helmer, 2010 .

Injury Risk Investigation of the Small, Rear-seat Occupant in Side Impact

Richard M. Morgan, Paul Scullion, Lilly Nix, 2012 .

Methodology for the Development and Evaluation of Active Safety Systems Using Reference Scenarios: Application to Preventive Pedestrian Safety

Paul Scullion, Randa Radwan Samaha, Thomas Helmer, 2010 .

Structural attributes of the striking vehicle that control aggressivity toward the struck-vehicle in frontal collisions

Richard M. Morgan, Paul Scullion, Kennerly Digges, 2009 .

Frontal Crashes Between the Longitudinal Rails

Richard M. Morgan, Paul Scullion, Kennerly H. Digges, 2011 .

Injury Mechanism of the Head and Face of Children in Side Impacts

Richard M. Morgan, Lilly Nix, Cing-Dao Kan, 2009 .

Frontal Crash Protection in Pre-1998 Vehicles versus 1998 and Later Vehicles

K. Digges, C. Kan, R. Morgan, 2010 .